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SBC: SA PHOTONICS, LLC Topic: SOCOM193001
CubeSats offer substantial reductions in operation and launch costs, while reducing time between request and employment of the capability. To address the USSOCOM needs, SA Photonics proposes an Infra-red Multispectral Imager for CubeSats (IMICS). IMICS collects diffraction-limited hyperspectral earth imagery, allowing identification of personnel, operating vessels / vehicles, structures and terrai ...SBIR Phase I 2020 Department of DefenseSpecial Operations Command
SBC: Skeyeon, Inc. Topic: SOCOM193001
Skeyeon, Inc. has developed all technologies necessary to orbit an Earth Observation, EO, satellite at 250 km, developing a vehicle design; atomic oxygen resistant, low drag materials; high bandwidth, real-time RF links; electric propulsion for 3 year missions; and a 1 meter resolution optical telescope compressed into a 10 cm high framework. A constellation of 100’s-1,000’s of these vehicles ...SBIR Phase I 2020 Department of DefenseSpecial Operations Command
Optimized Platforms for Proper Glycosylation and Sialylation of Recombinant Human Butyrylcholinesterase (rBChE)SBC: Technology Holding, LLC Topic: CBD192007
The threat of organophosphate (OP) chemical warfare agents (CWA) to United States military personnel is a persistent problem due to the relative ease of manufacturing chemical threats compared to nuclear and biological agents. Human butyrylcholinesterase (BChE) has been identified as a probable bio-scavenger of OP CWAs that could be used to protect individuals that could be exposed to OP CWAs. The ...SBIR Phase I 2020 Department of DefenseOffice for Chemical and Biological Defense
Optimized Platforms for Proper Glycosylation and Sialylation of Recombinant Human Butyrylcholinesterase (rBChE)SBC: ECHELON BIOSCIENCES, INC. Topic: CBD192007
Organophosphorus (OP) toxins and chemical warfare agents (CWA) are active nerve agents posing significant hazard for both soldiers and civilians. Butyrylcholinesterase (BChE) is a safe and effective bioscavenger that detoxifies OP and CWAs when injected either prophylactically or post-exposure; but a major technical problem has been producing a recombinant form of BChE with acceptable properties f ...SBIR Phase I 2020 Department of DefenseOffice for Chemical and Biological Defense
SBC: Integrated Solutions for Systems, Inc. Topic: CBD192002
The processes and systems required to decontaminate personnel have received much attention and several effective systems exist. However, decontamination of sensitive equipment, without damage or performance degradation, is a significantly different problem that has not been adequately solved. The wide variety of electronics, fabrics and structural materials together with the infinite variations in ...SBIR Phase I 2020 Department of DefenseOffice for Chemical and Biological Defense
Non-Invasive Monitoring of Changes in Intracranial Pressure Due to Infections in the Central Nervous SystemSBC: Fenix Research Corporation Topic: CBD192005
Infections of the central nervous system (CNS) are associated with brain swelling and increased cerebral blood volume, as well as focal cerebral perfusion deficits, variable levels of cerebral blood flow and cerebral vasculitis. The net result is increased intracranial pressure (ICP) along with significant risk of brain tissue herniation and ischemic syndromes. ICP monitoring is critical in the ma ...SBIR Phase I 2020 Department of DefenseOffice for Chemical and Biological Defense
Development of a Non-invasive Negative Ophthalmodynamometer Capable of Measuring Intracranial Pressure in HumansSBC: Equinox Ophthalmic, Inc. Topic: CBD192005
Measurement of intracranial pressure (ICP) is essential in the diagnosis and management of numerous life threatening conditions. All current methods used clinically to measure ICP are invasive and require direct access to the cerebrospinal fluid giving them a significant side effect profile. The ability to measure ICP non-invasively would be a major milestone for patients. Spontaneous venous pulsa ...SBIR Phase I 2020 Department of DefenseOffice for Chemical and Biological Defense
SBC: ARISAN THERAPEUTICS INC Topic: CBD192006
Arenaviruses comprise a diverse group of Old (Africa) and New World (Americas) species. Several species are associated with hemorrhagic fever (HF) with case-fatality rates as high as 30%. Arenaviruses infection typically occurs via the mucosal route through contact with excretions of an infected rodents although direct human-to-human transmission may occur in clinical settings. Lassa arenavirus en ...SBIR Phase I 2020 Department of DefenseOffice for Chemical and Biological Defense
SBC: ARISAN THERAPEUTICS INC Topic: CBD192006
Ebolavirus species including Zaire (EBOV), Sudan (SUDV) and Bundibugyo (BDBV) are responsible for severe hemorrhagic fever outbreaks with high case fatalities in Africa. Weaponized pathogens present an additional threat to the health protection of the warfighter and first-generation prophylactic and therapeutic medical countermeasures (MCMs) may prove inadequate in biodefense settings. Ebolaviruse ...SBIR Phase I 2020 Department of DefenseOffice for Chemical and Biological Defense
SBC: TOYON RESEARCH CORPORATION Topic: NGA191003
Due to the lack of consistency in existing automated methods for assigning VNIIRS levels to motion imagery, and the overwhelming human resources required to manually assign levels, a new method of automated/semi-automated VNIIRS assessment is needed. In recent years, advancements in deep learning have provided solutions to previously intractable computer vision problems. In many cases, automated d ...SBIR Phase I 2019 Department of DefenseNational Geospatial-Intelligence Agency