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SBC: ARISAN THERAPEUTICS INC Topic: CBD192006
Arenaviruses comprise a diverse group of Old (Africa) and New World (Americas) species. Several species are associated with hemorrhagic fever (HF) with case-fatality rates as high as 30%. Arenaviruses infection typically occurs via the mucosal route through contact with excretions of an infected rodents although direct human-to-human transmission may occur in clinical settings. Lassa arenavirus en ...SBIR Phase I 2020 Department of DefenseOffice for Chemical and Biological Defense
SBC: ARISAN THERAPEUTICS INC Topic: CBD192006
Ebolavirus species including Zaire (EBOV), Sudan (SUDV) and Bundibugyo (BDBV) are responsible for severe hemorrhagic fever outbreaks with high case fatalities in Africa. Weaponized pathogens present an additional threat to the health protection of the warfighter and first-generation prophylactic and therapeutic medical countermeasures (MCMs) may prove inadequate in biodefense settings. Ebolaviruse ...SBIR Phase I 2020 Department of DefenseOffice for Chemical and Biological Defense
Optimized Platforms for Proper Glycosylation and Sialylation of Recombinant Human Butyrylcholinesterase (rBChE)SBC: Technology Holding, LLC Topic: CBD192007
The threat of organophosphate (OP) chemical warfare agents (CWA) to United States military personnel is a persistent problem due to the relative ease of manufacturing chemical threats compared to nuclear and biological agents. Human butyrylcholinesterase (BChE) has been identified as a probable bio-scavenger of OP CWAs that could be used to protect individuals that could be exposed to OP CWAs. The ...SBIR Phase I 2020 Department of DefenseOffice for Chemical and Biological Defense
Optimized Platforms for Proper Glycosylation and Sialylation of Recombinant Human Butyrylcholinesterase (rBChE)SBC: ECHELON BIOSCIENCES, INC. Topic: CBD192007
Organophosphorus (OP) toxins and chemical warfare agents (CWA) are active nerve agents posing significant hazard for both soldiers and civilians. Butyrylcholinesterase (BChE) is a safe and effective bioscavenger that detoxifies OP and CWAs when injected either prophylactically or post-exposure; but a major technical problem has been producing a recombinant form of BChE with acceptable properties f ...SBIR Phase I 2020 Department of DefenseOffice for Chemical and Biological Defense
SBC: Space Micro Inc. Topic: SOCOM193001
Space Micro will develop an innovative payload that can be hosted onboard a nanosatellite/ CubeSat bus, for the advancement of USSOCOM capabilities in rapid intelligence collection, surveillance, and reconnaissance (ISR). This R&D will improve and enhance capabilities in intelligence collection, surveillance, and reconnaissance from new spaceborne platforms.SBIR Phase I 2020 Department of DefenseSpecial Operations Command
SBC: SA PHOTONICS, LLC Topic: SOCOM193001
CubeSats offer substantial reductions in operation and launch costs, while reducing time between request and employment of the capability. To address the USSOCOM needs, SA Photonics proposes an Infra-red Multispectral Imager for CubeSats (IMICS). IMICS collects diffraction-limited hyperspectral earth imagery, allowing identification of personnel, operating vessels / vehicles, structures and terrai ...SBIR Phase I 2020 Department of DefenseSpecial Operations Command
SBC: Skeyeon, Inc. Topic: SOCOM193001
Skeyeon, Inc. has developed all technologies necessary to orbit an Earth Observation, EO, satellite at 250 km, developing a vehicle design; atomic oxygen resistant, low drag materials; high bandwidth, real-time RF links; electric propulsion for 3 year missions; and a 1 meter resolution optical telescope compressed into a 10 cm high framework. A constellation of 100’s-1,000’s of these vehicles ...SBIR Phase I 2020 Department of DefenseSpecial Operations Command
SBC: TOYON RESEARCH CORPORATION Topic: SOCOM201003
Toyon Research Corp. proposes a feasibility study including all promising techniques for enabling SOCOM’s desired Multi-FMV Fusion 3D Capability, which is intended to reduce operator cognitive burden and enhance multi-source surveillance data exploitation. Key topics to consider include multi-platform FMV registration and fusion, 3D model reconstruction, fused video rendering, and artificial int ...SBIR Phase I 2020 Department of DefenseSpecial Operations Command
SBC: BOTTS INNOVATIVE RESEARCH INC Topic: SOCOM202001
Botts Innovative Research, Inc (Botts, Inc.) proposes to conduct a feasibility study to assess the art of the possible as it relates to the use of the open source, open standards based OpenSensorHub (OSH) (www.OpenSensorHub.org) for the integration between the sensors and robots of Hyper Enabled Operators (HEO), their units, and their mission command, to provide battlespace awareness at the tactic ...SBIR Phase I 2020 Department of DefenseSpecial Operations Command
SBC: INNOSENSE CORPORATION Topic: CBD181004
Chemical warfare agents such as the lethal nerve agent soman are a major source of risk to military personnel. Currently, pyridostigmine bromide (PB) is the only FDA-approved pretreatment to counteract the effects of soman. The rationale behind PB administration is that it acts as a “temporary” inhibitor of AChE. This precludes nerve agents from irreversible inactivation of AChE, thereby mitig ...SBIR Phase I 2019 Department of DefenseOffice for Chemical and Biological Defense