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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

  1. Precision quality check of immunotherapeutics via single-cell cytokine mapping

    SBC: IsoPlexis            Topic: 102

    Adoptive transfer of autologous T cells engineered to express chimeric antigen receptorsCARshas emerged as a promising immunotherapy for patients with hematologic malignanciessuch as CDCARs in leukemias and lymphomasHoweverchallenges remain in terms of manufacturing consistency and the functional profile of the CAR T cell productsince infused cellsasliving drugscan be activated and release a varie ...

    SBIR Phase II 2017 Department of Health and Human Services
  2. A Novel, Nanostructured, Metal-organic Frameworks-Based Product Loss Prevention Technology in the Oil and Natural Gas Sector

    SBC: Framergy, Inc.            Topic: 17NCER2C

    To reach the end user, oil and gas production at the wellhead must be transmitted through the country and distributed to a wide range of customers. This logistical system requires natural gas gathering lines, processing facilities, product storage tanks and lots of other equipment. What results is air pollution caused by industry losses during these operations and the use of continuous or intermit ...

    SBIR Phase I 2018 Environmental Protection Agency
  3. Multicore Fiber Optic Package Optical Subassembly for Wideband Digital and Analog Photonic Links

    SBC: PHASE SENSITIVE INNOVATIONS            Topic: N182101

    In this SBIR effort we will develop a balanced detection analog photonic link consisting of a DFB laser, a dual-output high-speed, low-Vp mach-zehnder modulator (MZM) and a high-power, high-linearity balanced photodetector (BPD) using a dual-core, single mode, multicore fiber (MCF) that is supplied by our subcontractor, OFS. We will design, fabricate and characterize (phase I) the MZM and the BPD, ...

    SBIR Phase I 2018 Department of DefenseNavy
  4. Single-cell Phosphoprotein Assay to Evaluate Brain Tumor Therapeutic Resistance

    SBC: IsoPlexis            Topic: 102

    Although signal transduction inhibitors occasionally offer clinical benefit for cancer patientssignal flux emanating from oncogenes is often distributed through multiple pathwayspotentially underlying the resistance which causes failure of most such inhibitorsMeasuring signal flux through multiple pathwaysin response to signal transduction inhibitorsmay help uncover network interactions that contr ...

    SBIR Phase I 2018 Department of Health and Human Services
  5. Hyperspectral Microwave Photonic Radiometer

    SBC: PHASE SENSITIVE INNOVATIONS            Topic: S1

    Passive Microwave Remote Sensing is currently utilized by NASA, NOAA, and others to conduct Earth Science missions, including weather forecasting, early warning systems, and climate studies. These sensors could also be used in upcoming missions such as Saturn’s moon to study atmospheric makeup.  On earth, humidity and temperature sounding is conducted near several absorption lines to de ...

    SBIR Phase I 2018 National Aeronautics and Space Administration
  6. Radiation-Hardened CubeSat Power Management & Distribution (PMAD) for Europa Environment

    SBC: Ragnarok Industries Inc            Topic: S4

    In Phase 1, Ragnarok will mature the much-needed rad-hard BCDR technology from TRL 3 - 4. Phase 2 of Ragnarok’s efforts will proceed to develop the entire functional prototype radiation-hardened PMAD system including the newly developed BCDR hardware from Phase 1. Phase 2 efforts will conclude with a full Critical Design Review (CDR) and a completed and closed list of HRs and HRMPs. The ...

    SBIR Phase I 2018 National Aeronautics and Space Administration
  7. A Combined High-Throughput Single-Cell Transcriptomic and Secretomic Assay for Neurodegenerative Disease Biomarker Discovery

    SBC: IsoPlexis            Topic: 105

    In this Phase I application IsoPlexis proposes to deliver a novel method for targeted profiling of both the transcriptome and secretome from an array ofsingle central and peripheral immune cellsSpecificallywe will deliver a single cellmRNA and secreted protein capture assay with proven sensitivity for detecting the most important predictive biomarkers for neurodegenerative diseasesThere is growing ...

    SBIR Phase I 2018 Department of Health and Human Services
  8. Additive Manufacturing for RF Materials and Antennas

    SBC: DeLUX Engineering, LLC            Topic: A18020

    To reduce size, weight, power and cost (SWaP-c), military platforms have been evolving towards more integrated platforms that utilize all available space. For radiating systems, this will require exploring innovative design methods, materials and manufacturing approaches to realize cost-effective, customizable and conformal antennas. An attractive solution to this challenge is offered by additive ...

    SBIR Phase I 2018 Department of DefenseArmy
  9. Low-cost Imager for Heavily Degraded Visual Environments

    SBC: PHASE SENSITIVE INNOVATIONS            Topic: A18040

    This project aims to develop a low-cost millimeter-wave (mmW) imaging system for ground vehicles, to operate in combination with a long-wave infrared (LWIR) camera. Such a system will mitigate the challenges of driving in degraded visual environments (DVE) including night time, fog, dust, or smoke by providing real-time image of the vehicle surrounding independent from the presence of naturally oc ...

    SBIR Phase I 2018 Department of DefenseArmy
  10. "Night Glow" Short Wave Infrared LED (NSLED) Image Projector Development

    SBC: Chip Design Systems            Topic: AF131098

    ABSTRACT:We propose to develop and demonstrate component technologies, interfaces, and software necessary to build a prototype Short Wave Infrared (SWIR) projection system with high dynamic range and fast frame rates. More specifically, final hardware deliverables for this project include three (3) tested hybrid modules that integrate a 1024x1024 24-micron pitch SWIR LED emitter array with a match ...

    SBIR Phase II 2014 Department of DefenseAir Force

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