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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

  1. Improved Dehydration Process for Pharmaceutical Synthesis

    SBC: COMPACT MEMBRANE SYSTEMS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Most pharmaceutical synthesis involve condensation or dehydration reactions at some point in the process that generates water as a by-product. This water must be removed since (1) water is often not a desirable component of the finished product, (2) water limits conversion to final product, and (3) water generated slows the reaction rate. Many Pharmaceuticals h ...

    SBIR Phase I 2006 Department of Health and Human Services
  2. High Flux Blood Oxygenators

    SBC: COMPACT MEMBRANE SYSTEMS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Historically blood oxygenator technology either for short-term by-pass surgery or recently developed long-term strategies has been mass transfer limited by liquid side mass transfer fluid dynamics. Recent active mixing designs have led to systems which remove liquid side fluid limitations and have oxygen and carbon dioxide transport limited by membrane transpo ...

    STTR Phase I 2006 Department of Health and Human Services
  3. Computer Adaptive Testing of Pediatric Self-care and Social Function

    SBC: CRECare LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The objective of this proposed project is to achieve a major transformation in the technology used to assess self-care and social disability in children and youth. Measurement and practical requirements to identify disability and evaluate individual progress across pediatric age-groups and care settings present a serious dilemma to current fixed-item instrument ...

    STTR Phase I 2006 Department of Health and Human Services
  4. A Novel Diagnostic Test to Detect Vitamin B12 Deficiency

    SBC: METABOLIC SOLUTIONS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Vitamin B12 deficiency is a common problem that affects the general US population and the elderly in particular. The elderly are at risk for preclinical vitamin B12 deficiency due to the increased presence of B12 malabsorption and atrophic gastritis as a consequence of aging. The deficiency of vitamin B12 in the elderly has potentially serious complications inc ...

    SBIR Phase II 2006 Department of Health and Human Services
  5. Rapid Susceptibility Testing of MDR M. tuberculosis- Phase II

    SBC: MIDI, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The long-term objective of this project is the development of a system based on high performance liquid chromatography (HPLC) for rapid and accurate antibiotic susceptibility testing of Mycobacterium tuberculosis (MTB). Susceptible and resistant strains of MTB, exposed to anti-MTB antibiotics, exhibit pronounced differences in mycolic acid content. Initial rese ...

    SBIR Phase II 2006 Department of Health and Human Services
  6. Narrow-Band Active Noise Reduction for DPOAE Measurement

    SBC: CREARE LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The aim of this project is to enable accurate acquisition of distortion product otoacoustic emission (DPOAE) measurements in relatively high noise environments for use in hearing evaluations and screening. DPOAE measurements have been shown to be an effective and efficient method for screening infant, child, and adult hearing. Environmental noise, however, can ...

    SBIR Phase II 2006 Department of Health and Human Services
  7. A Novel Liquid Oxygen Recharger for Home Oxygen Therapy

    SBC: CREARE LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The specific aim of this project is to develop and demonstrate a low-cost, liquid oxygen (LOX) generation system to support ambulatory patients using Home Oxygen Therapy (HOT). Currently in the United States, yearly expenditures on HOT are nearly two billion dollars. These expenditures will increase dramatically over the next ten years due to the aging baby-boo ...

    SBIR Phase II 2006 Department of Health and Human Services
  8. An Intelligent Physical Activity Monitor

    SBC: CREARE LLC            Topic: N/A

    DESCRIPTION (provided by applicant): There is a recognized need for specific and reliable information regarding the dose/response relationships between physical activity and health for all segments of the population. New methods for assessing physical activity and energy expenditure (EE) in free-living populations are needed before a systematic evaluation and interpretation of these dose-response ...

    SBIR Phase I 2006 Department of Health and Human Services
  9. Hemodynamic Assessment of Renal Artery Disease

    SBC: CREARE LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The overall goal of this research is the development of a diagnostic methodology for predicting whether treatment of atherosclerotic stenoses in the renal artery will provide sufficient benefit in controlling hypertension or maintaining renal function to offset the risks of the treatment. Stenoses in the renal artery are comparatively common, yet prior studies ...

    STTR Phase I 2006 Department of Health and Human Services
  10. A Novel Caries Prevention and Treatment System

    SBC: CREARE LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The specific aim of this research program is the development of a low-cost, laser-based caries prevention and treatment system to effectively reduce or eliminate caries in children and adults. Even with the substantial decline in caries that has occurred over the last several decades, a substantial percentage of children and adults have evidence of untreated ca ...

    SBIR Phase I 2006 Department of Health and Human Services

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