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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

Displaying 51 - 60 of 23070 results
  1. Commercializing Praedicare Dx TM platform for guiding cancer treatments

    SBC: Eutropics Pharmaceuticals, Inc.            Topic: 102

    Abstract The Eutropics PraediCare Dxis an emerging clinical diagnostic assay that will be used to predict patient response to specific chemotherapiesUnlike existing assaysPraediCare Dxpredicts response to specific chemotherapies by direct evaluation of cancer cells potential to enter into an apoptotic state following exposure to therapyPraediCare Dxhas the potential to provide actionable data for ...

    SBIR Phase II 2017 Department of Health and Human Services
  2. STTR Phase II: Connected low-power wearable technology that provides personalized thermal comfort in offices

    SBC: Embr Labs, Inc            Topic: I

    The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase II project is to make significant contributions to the future of thermal environmental conditioning in buildings throughout the world. The connected, low power, wearable personal comfort systems can provide relief for the thermally-underserved of America's workforce (who are disproportionately female or ...

    STTR Phase II 2018 National Science Foundation
  3. SBIR Phase II: Virtual Learning Assistants for Open Response Assessments

    SBC: Cognii, Inc.            Topic: EA

    This SBIR Phase II project focuses on creating scalable Virtual Learning Assistant technology for automatic educational assessments using open response questions. Educational researchers and experts believe that the best pedagogies responsible for improving students' learning outcomes involve (i) open response questions assessments and (ii) one-to-one instructional tutoring. Students learn better ...

    SBIR Phase II 2018 National Science Foundation
  4. SBIR Phase II: Robust Nanofiltration to Enable Challenging Chemical and Pharmaceutical Separations

    SBC: Via Separations, LLC            Topic: MN

    This SBIR Phase II project focuses on advancing the domestic manufacturing capabilities for high-value nanomaterials for new membrane materials. Previously, the company has developed a novel membrane material with considerable economic, environmental, and nutritional impact in industrial process applications. Commercially available nanofiltration (NF) membrane systems employ polymer membranes, whi ...

    SBIR Phase II 2018 National Science Foundation
  5. SBIR Phase II: Novel Formulation for the Delivery of High Concentration Protein Therapeutics

    SBC: Elektrofi Inc            Topic: BM

    This SBIR Phase II project aims to transform intravenous (IV) infusions of biologic medicines into simple subcutaneous (SC) injections. Biologics have improved the treatment of human disease. Unfortunately, their delivery is burdensome. The standard of administration of these biologics is often by IV infusion at low concentrations, which can take multiple hours to deliver, cause patient discomfort ...

    SBIR Phase II 2018 National Science Foundation
  6. Multi-modal AO-LSO Phase Gradient Imaging of the Inner Retina

    SBC: MixZon, Inc.            Topic: NEI

    Project Summary Abstract Physical Sciences IncPSIis continuing the pursuit of new clinical applications and advanced multimodal capabilities for its novel retinal imaging technology based on an adaptive optics line scanning ophthalmoscopeAO LSOThe Compact Adaptive Optics Retinal ImagerCAORIeliminates high speed scanning componentsreduces the clinical footprint compared to research adaptive optics ...

    SBIR Phase II 2018 Department of Health and Human Services
  7. Antibody targeting of ADAM8 for treatment of triple-negative breast cancer

    SBC: Adecto Pharmaceuticals, Inc.            Topic: NCI

    Triple negative breast cancersTNBCsaccount forof breast cancer deaths and lack targeted therapiesWe identified the non essentialcell surface protein ADAMas an important target on TNBCADAMis present inof primary TNBCsandof all breast cancer patient derived metastasesbut absent in normal breast tissuesHigh ADAMmRNA levels correlate with poor patient outcomeThe ADAMMetalloproteinaseMPand DisintegrinD ...

    SBIR Phase II 2018 Department of Health and Human Services
  8. NAAA Inhibition for Pain and Inflammation

    SBC: NeoKera, LLC            Topic: 103

    PROJECT SUMMARY Pain management is a significant unmet medical needPalmitoylethanolamidePEAis an endogenous analgesic substance that plays crucial roles in the peripheral control of pain and inflammationIts biological actions are terminated by the cysteine hydrolaseN acylethanolamine acid amidaseNAAADuring the Phaseof the present SBIRapplicationwe have developed the first class of potentselective ...

    SBIR Phase II 2018 Department of Health and Human Services
  9. Preventing and Reducing HAND by Using New BDNF Nanoprobes

    SBC: ExQor Technologies Inc            Topic: 105

    Human immunodeficiency virusHIVassociated neurocognitive disorderHANDrepresents a major chronic health problem in the US and abroadMagnetic Resonance ImagingMRIstudies have consistently shown brain gray and white matter abnormalities and cognitive deficits in patients with HANDAdvances in treatment of HAND have been made by delivering drugs or viral vectors that can increase brain derived neurotro ...

    SBIR Phase II 2018 Department of Health and Human Services
  10. A technology solution for peer-led Seeking Safety

    SBC: LMN CONSULTING            Topic: NIDA

    AbstractPeers are increasingly recognized as an important asset in healthcarePeer support is historically most prominent for substance use disorderSUDsuch as the world wide model of Alcoholics Anonymous and otherstep groupsYet for trauma and posttraumatic stress disorderPTSDthere have been few attempts at peer helpA major challenge of trauma peer groups is that they usually focus on telling the st ...

    SBIR Phase II 2018 Department of Health and Human Services

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