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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Progenitor assay to screen proteins/molecules for treatment of type1 diabetes

    SBC: BETASTEM THERAPUETICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Human embryonic stem cells (HuES) have the potential to generate an unlimited source of beta/islet cells for transplantation, however the biologic factors required for this process have been difficult to ascertain partly due to the lack of stage specific in vitro cell assays. Recently, we have developed a murine in vitro pancreatic stem/progenitor colony assay ...

    STTR Phase I 2007 Department of Health and Human Services
  2. SBIR TOPIC 241- TARGETED NANOPARTICLES FOR PROSTATE CANCER THERAPY

    SBC: BIND BIOSCIENCES, INC.            Topic: N/A

    N/A

    SBIR Phase I 2007 Department of Health and Human Services
  3. SBIR TOPIC 229 A ROBUST AND RIGOROUS PHARMACODYNAMIC ASSAY FOR AKT

    SBC: BIOASSAY SYSTEMS, LLC            Topic: N/A

    N/A

    SBIR Phase I 2007 Department of Health and Human Services
  4. SBIR TOPIC 229 A ROBUST AND RIGOROUS PHARMACODYNAMIC ASSAY FOR PTP1B

    SBC: BIOASSAY SYSTEMS, LLC            Topic: N/A

    N/A

    SBIR Phase I 2007 Department of Health and Human Services
  5. Cloning, overexpression and characterization of novel alkene reductases

    SBC: BIOCATALYTICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Reduction of carbon-carbon double bonds (C=C) is a fundamental reaction in synthetic organic chemistry. The ability to control the regio-, and stereo-, and chemo selectivity of reduction is of particular importance when designing new hydrogenation catalysts. For example, the chemo-selective reduction of C=C bonds that are conjugated to carbonyl groups has been ...

    SBIR Phase I 2007 Department of Health and Human Services
  6. DEVELOPMENT OF AN ELECTRICAL DIAGNOSTIC FOR MELANOMA

    SBC: BIOELECTROMED CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): RPN Research has developed a new medical device, the Bioelectric Field Imager (BFI) which can measure the electric field in human skin non-invasively. The hand-held BFI scans a vibrating sensor over the skin without making contact with it and plots the surface potential distribution over a 1 cm distance in about 1 minute. Using a table-mounted version of this n ...

    SBIR Phase II 2007 Department of Health and Human Services
  7. Pyrophosphorolysis-activatable helicase dependent amplification assay for lung ca

    SBC: BIOHELIX CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): Aside for a vast minority of asymptomatic patients diagnosed incidentally, virtually all lung cancer patients are symptomatic at presentation. As a result only 30-35% of patients have sufficiently localized tumors to allow for surgical resection of the tumor. Cancers over expressing the epidermal growth factor receptor (EGFR) have been shown to increase ...

    SBIR Phase I 2007 Department of Health and Human Services
  8. Development of a novel whole genome amplification method that mimics nature

    SBC: BIOHELIX CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): BioHelix is the exclusive licensee for the commercialization of a novel, primase- based Whole Genome Amplification (pWGA) technology invented by Drs. Stanley Tabor and Charles Richardson at Harvard Medical School. This pWGA system utilizes multiple replication proteins including a primase/helicase, a DNA polymerase, a single- stranded DNA binding protein, and ...

    SBIR Phase I 2007 Department of Health and Human Services
  9. Ultrafiltration Device for Rapid, High, Through-put Sample Preparation

    SBC: BIOLINK PARTNERS            Topic: N/A

    DESCRIPTION (provided by applicant): The goal of this project is to develop advanced ultrafiltration (UF) devices for sample preparation that are faster and easier to use than existing devices. New technology based on proprietary concepts enables ultrafiltration to be practiced at low pressure, and without the need of centrifuges or other complex apparatus, resulting in a single-pass, tangential-f ...

    SBIR Phase I 2007 Department of Health and Human Services
  10. Phenotype MicroArray Analysis of Fastidious Pathogens

    SBC: BIOLOG, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Mycobacterium tuberculosis and other Mycobacterium species are major pathogens around the world. They are part of a larger group of so-called fastidious pathogens that are difficult to study because, for a wide range of reasons, they are difficult to culture. Phenotype MicroArrayTM (PM) technology is a tool that can aid in understanding the physiological and me ...

    STTR Phase II 2007 Department of Health and Human Services

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