Award Data

DESCRIPTION provided by applicant Individuals with dysvascular amputation often undergo additional higher level amputations due to a progression of the underlying disease It can be calculated that nearly $ billion is spent each year in the United States on costs related to reamputation of dysvascular residual limbs that had undergone a previously healed amputation In addition to the subs ...

DESCRIPTION provided by applicant Akston Biosciences Corp is developing a subcutaneously administered therapeutic for preventing or delaying the onset of diabetes in pre diabetic patients who are at high risk those who display autoantibodies for insulin GAD IA and ZnT for developing Type diabetes T D The therapeutic is designed to delete a subset of B cells that likely play a ro ...

Enter the text here that is the new abstract information for your application This section must be no longer than lines of text Substance use disorder SUD is a chronic relapsing disease However current systems of care typically respond to SUD as an acute problem requiring short term residential and or outpatient treatment As currently treated people with SUD continue to have high relap ...

DESCRIPTION provided by applicant There is currently no therapy for Amyotrophic Lateral Sclerosis ALS which is a universally fatal neurodegenerative disease that afflicts over out of every individuals Protein aggregation has been implicated as a primary driving force in ALS and multiple other neurodegenerative illnesses TDP is the principle component of the protein aggregates i ...

DESCRIPTION provided by applicant The technology that is routinely available to neuroradiologists is years or decades behind that which is used in imaging research throughout the world Current clinical decision making in neuroradiology is based on information that is insufficient for detecting the subtle changes that presage clinically significant conditions such a a growing tumor enlarging v ...

DESCRIPTION provided by applicant Foodborne illnesses devastate on the gastrointestinal microflora of millions of Americans each year often resulting in dysbiosis and increase risk of other diseases namely irritable bowel syndrome kidney failure pancreatitis and diabetes Furthermore diabetics are at increased risk of developing a foodborne illness and they often take longer to recover T ...

DESCRIPTION provided by applicant Dichloroacetate DCA has therapeutic potential in treating several rare and common life threatening diseases of children and adults These include congenital pyruvate dehydrogenase complex deficiency PDCD pulmonary arterial hypertension PAH diabetes heart disease cancer and other diseases in which it has been investigated as a therapeutic However DCA ...

Braking Rate Monitoring and Warning System 3/9/2015 Driver inattention and inaction are a major cause for serious crashes. There is a need for a low cost auxiliary system to sense any rail vehicle approaching unsafely and alert drivers. The auxiliary system will provide some form of Human Machine Interface that may aggressively alert the train operator of potential safety problems and permit a r ...

Triton, proposes to develop a device to be used in the temporary management of corneal injury following ocular trauma.

DESCRIPTION provided by applicant Portable Multimode Persufflation Perfusion System for Extended Hypothermic Kidney Preservation In over patients in the US started treatment for end stage renal disease ESRD These patients spend on average $ annually on treatment including dialysis In The U S the current waiting list for organ transplantation holds over patient ...