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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. AN EPIDEMIOLOGIC TOOL TO DETECT ANGINA PECTORIS IN BLACKS

    SBC: New England Research Institutes, Inc.            Topic: N/A

    ANGINA PECTORIS IS OFTEN CONSIDERED A MANIFESTATION OF CORONARY ARTERY ATHEROSCLEROSIS THAT IS ASSOCIATED WITH AN INCREASED MORTALITY RISK. OVERALL, CORONARY HEART DISEASE IS THE LEADING CAUSE OF MORBIDITY AND MORTALITY IN U.S. BLACKS. IN AN ATTEMPT TO STANDARDIZE THE DIAGNOSIS OF ANGINA PECTORIS IN EPIDEMIOLOGIC STUDIES, ROSE DEVELOPED A QUESTIONNAIRE FOR CARDIOVASCULAR FIELD SURVEYS WHICH HAS PR ...

    SBIR Phase I 1988 Department of Health and Human Services
  2. A TELEPHONE-LINKED COMPUTER SYSTEM FOR ELDER CARE

    SBC: New England Research Institutes, Inc.            Topic: N/A

    THE TELEPHONE-LINKED COMPUTER (TLC) SYSTEM HAS BEEN DEVELOPED AND TESTED TO CONVERSE AUTOMATICALLY BY TELEPHONE,USING COMPUTER-GENERATED SPEECH, WITH INDIVIDUALS IN ORDER TO MONITOR THEIR HEALTH STATUS, REPORT THE FINDINGS TO THEIRPROVIDERS OF CARE, AND GIVE THE PATIENTS INFORMATION AND FEEDBACK THAT REINFORCE DESIRABLE SELF-CARE ACTIVITIES. THELONG-TERM OBJECTIVE OF THE PROPOSED PROJECT IS TO DEV ...

    SBIR Phase I 1988 Department of Health and Human Services
  3. OF CELLS SYNCHROTRON X-RAY FLUORESCENCE MICRO-TOMOGRAPHY OF CELLS

    SBC: Radiation Science, Inc.            Topic: N/A

    THE OBJECTIVE OF THIS PROGRAM IS TO DEVELOP A RESEARCH RESOURCE FOR STUDYING THE ROLE OF TRACE ELEMENTS IN CELLULARPROCESSES BY LOCALIZING THE ELEMENTS WITHIN THE ORGANELLES OF THE CELL USING MICRON SCALE COMPUTED TOMOGRAPHY (CT) OF SYNCHROTRON INDUCED FLUORESCENT X-RAYS. BECAUSE FLUORESCENCE CT NEEDS ONLY MINIMALLY PREPARED, THICK SAMPLES, THE PROBABILITY OF CONTAMINATION SHOULD BE MUCH LOWER THA ...

    SBIR Phase I 1988 Department of Health and Human Services
  4. HIGH AFFINITY LIGANDS FOR THE COCAINE RECEPTOR

    SBC: Research Biochemicals,            Topic: N/A

    N/A

    SBIR Phase I 1988 Department of Health and Human Services
  5. SYNTHESIS OF FLUORESCENT PROBES FOR MONITORING BRAIN RECEPTOR MOBILITY

    SBC: Research Biochemicals,            Topic: N/A

    N/A

    SBIR Phase I 1988 Department of Health and Human Services
  6. AFFINITY MEMBRANE DEVICE FOR SELECTIVE CELL SEPARATIONS

    SBC: SEPRACOR, INC.            Topic: N/A

    THE PROPOSED PROGRAM IS DESIGNED TO DEMONSTRATE THE FEASIBILITY OF A SUPERIOR, HIGHLY CONTROLLABLE AND PRODUCTIVE AFFINITY MEMBRANE DEVICE AND PROCESS FOR THE HIGH-RESOLUTION SEPARATION OF PARTICULAR CELL SUBSETS FROM COMPLEX BIOLOGICAL FLUIDS. CELL SEPARATION IS ACCOMPLISHED BY EXPOLITING HIGHLY SPECIFIC INTERACTIONS THAT TAKE PLACE BETWEEN CELL SURFACE RECEPTORS AND THEIR CORRESPONDING IMMUNOAFF ...

    SBIR Phase I 1988 Department of Health and Human Services
  7. MEMBRANE IMMUNOAFFINITY PURIFICATION OF FACTOR VIII:C

    SBC: SEPRACOR, INC.            Topic: N/A

    N/A

    SBIR Phase I 1988 Department of Health and Human Services
  8. A NEW LUTEINIZING HORMONE TEST FOR OVULATION DETECTION

    SBC: Standard Scientifics Inc.            Topic: N/A

    N/A

    SBIR Phase I 1988 Department of Health and Human Services
  9. MICRO- EXTRACTION DEVELOPMENT FOR DRUG ASSAY

    SBC: SYMBIOTECH, INC.            Topic: N/A

    THE INTERFACE BETWEEN TWO CONTIGUOUS, IMMISCIBLE LIQUID PHASES CAN BE ESTABLISHED WITHIN THE MICROPORES OF A NEW TYPE OF POLYMERIC MEMBRANE. THESE KINDS OF MEMBRANES IN THEFORM OF TINY HOLLOW FIBERS WILL BE INVESTIGATED FOR CONDUCTING LIQUID-LIQUID EXTRACTION AS A FIRST PURIFICATION STAGE IN THE ASSAY OF DRUGS. THE TECHNOLOGY IS APPLICABLE TO VERY SMALL SAMPLES AND SHOULD ALSO FIND USE IN THE ASSA ...

    SBIR Phase I 1988 Department of Health and Human Services
  10. HIGHLY ADHERENT COATINGS FOR BIOSENSORS

    SBC: Tekmat Corp            Topic: N/A

    NUMEROUS IMPLANTABLE BIOSENSORS HAVE BEEN DEVELOPED, BUT NONE HAVE REACHED COMMERCIAL VIABILITY DUE TO SALINE CORROSION OVER EXTENDED PERIODS. A COATING TECHNIQUE IS PROPOSED WHICH WILL COMBINE THE STRONG ADHERENCE OF PLASMA POLYMERIZED THIN FILMS WITH THE EASE AND SIMPLICITY OF DIP COATINGS. DURING PHASE I, THE NOVEL TECHNIQUE WILL BE APPLIED TO BIOSENSOR PROBES AND LEADS. THE COATINGS WILL BE EV ...

    SBIR Phase I 1988 Department of Health and Human Services

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