Award Data

DESCRIPTION (provided by applicant): Research and development of new drugs is a protracted and expensive endeavor. The typical drug discovery process evolves from lead identification for a disease target to lead optimization, in vitro/in vivo evaluation, preclinical and clinical testing, and FDA approval. Several studies estimate the average cost of development of a single, approved new drug in ex ...

DESCRIPTION (provided by applicant): In the current economic climate, community colleges are playing a more vital role than ever in educating the workforce. Enrollment at community colleges has grown by 17 percent since fall 2007 to a total enrollment of 8million (AACC, 2010a). Moreover, President Obama has called on community colleges to produce five million more graduates by 2020 (Gonzalez, 2010 ...

Tactical counter-insurgency (COIN), counter-terrorism, and anti-piracy operations require a combination of human and machine-based ISR collections to be accelerated through the Processing, Exploitation, and Dissemination (PED) processes of small units. Lightweight mobile communication and computing devices together with highly portable ground-based and small UAS sensors are rapidly enabling new CO ...

DESCRIPTION (provided by applicant): This Phase II application continues development of the Pain Assessment Interview Network - Clinical Advisory System (painCAS), a systematic and tested computer-administered assessment of chronic pain patients. Initial Assessment and Follow-up modules assess relevant health and functioning information of patients as they enter or continue treatment for chronic p ...

DESCRIPTION (provided by applicant): Gene therapy in the context of diabetic kidney disease holds tremendous promise, although concrete progress in the field has been difficult to achieve. Specifically, the growth factor TGF-2 is known to play a critical role in glomerular matrix expansion and progression of glomerular fibrosis, and inhibition of TGF-2 activity by neutralizing antibodies has shown ...

DESCRIPTION (provided by applicant): The overall objective for this project is to validate, commercialize, and further establish the clinical utility of a comprehensive set of genotyping assays to improve screening and diagnosis of conditions associated with fragile X syndrome (FXS). The relevance of testing for interspersed AGG sequences in CGG repeats has been proposed from population studies of ...

Next generation EO/IR sensors are needed for a variety of Military Systems Applications. These include UV, Visible, NIR, SWIR, MWIR and LWIR bands. Magnolia as part of the proposed Phase II STTR Program plans to design, model and develop Strained Layer Superlattice (SLS) based detector array for next generation multicolor IR imaging applications. The key components of the Program will include eva ...

DESCRIPTION (provided by applicant): The proposed project is designed to fill an extremely important yet unmet need by developing an alternative training mechanism that has the potential for reaching all personnel responsible for risk management and quality improvement in programs that provide services to persons with mental retardation/developmental disabilities (MRDD) and the public agency staff ...

The U.S. Navy has initiated a program to develop the next-generation Joint Counter Radio Controlled Improvised Explosive Device Electronic Warfare (JCREW) 3.3 system to detect and jam enemy improvised explosive devices (IEDs). The objective of this proposed effort is to develop the manufacturing processes and antenna designs needed to integrate a wideband metamaterial antenna within the ballistic ...

SI2 Technologies, Inc. (SI2) proposes to design and develop a multifunction conformal antenna system for UHF Flight Termination System (FTS), L-band Global Positioning System (GPS), and S-band Telemetry applications for the SM-3 family of missiles and other platforms. To reduce the depth of protrusion, axial length, and weight of the multifunction antenna while maintaining wide bandwidth and high ...