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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Selective inhibition of CYP26A1 in the skin for the treatment of ichthyosis
SBC: DERMAXON LLC Topic: NIAMSProject Summary Abstract DermaXon s project goal is to develop efficacious novel selective inhibitors of CYP A for the topical treatment of ichthyosis Congenital ichthyosis is a family of hereditary disorders of keratinization characterized by dry scaling skin that may be thickened or very thin impacting the quality of life of patients and their family members Currently there is no cure f ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
Novel antibacterial agents derived from natural products
SBC: Promiliad Biopharma Incorporated Topic: NIAIDDESCRIPTION provided by applicant Antibiotic resistance among common bacterial pathogens is a serious public health problem as it compromises our ability to treat infectious disease The resistance problem is compounded by the lack of discovery of new antibiotics especially those with novel mechanisms of action New antibiotics are critically needed as resistance to recently developed antibiot ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
Screening the Ribosome for New Target Sites
SBC: NUBAD LLC Topic: NIAIDDESCRIPTION provided by applicant Nucleic acids are avenues for drug design both as therapeutics and as targets Here we propose to establish new methods for identifying antibiotic ribosome targets and lead compounds Targeting specific RNA such as rRNA which are involved in proliferation and survival of bacteria is a promising approach We are developing fast and low cost methods to screen s ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
Smart Residential Carpet for Promoting Aging in Place
SBC: BIOSENSICS LLC Topic: NIADESCRIPTION provided by applicant Aging in place or the ability of older adults to continue to live safely and economically in their own residences for as long as possible is one of the key issues of modern societies Continued population growth of older adults age will lead to significant financial and logistical burdens on the nationandapos s healthcare system As the population ages ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
T SS needle protein inhibitors for the treatment of P aeruginosa infection
SBC: MICROBIOTIX, INC. Topic: NIAIDDESCRIPTION provided by applicant The inability to treat many Gram negative bacterial infections effectively with existing antibiotics is a major medical crisis Pseudomonas aeruginosa is a prime example of clinical isolates from critically ill patients are resistant to three or more drugs The overall goal of this project is to address the critical medical need by a novel approach of iden ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
Proteasome inhibitor re-sensitizing molecules for treatment of refractory multiple myeloma
SBC: LEUKOGENE THERAPEUTICS INC Topic: 102Project Summary Abstract Multiple Myeloma MM is the second most common form of blood cancer and remains an incurable and deadly disease Proteasome inhibitor PI therapy is a cornerstone in the treatment of MM but resistance to this class of agent is an emerging challenge in the clinic New therapeutic approaches that specifically target resistance are needed to maximize responses and ultimate ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
Development of Alkontrol herbal for Treating Alcohol Abuse
SBC: NATURAL PHARMACIA INTERNATIONAL, INC. Topic: NIAAADESCRIPTION provided by applicant This application for a Fast Track STTR award represents a collaboration between Natural Pharmacia International Inc NPI and McLean Hospital to initiate steps toward commercializing a isoflavone botanical product for treating alcoholism Excessive use of alcohol accounts for much of the public health burden related to alcohol use disorders including fetal a ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
Development of PAR Pepducins for the Treatment of Atopic Dermatitis
SBC: OASIS PHARMACEUTICALS, LLC Topic: NIAMSDESCRIPTION provided by applicant Atopic dermatitis AD or severe eczema is a very common life long skin disease with of adults in the US requiring systemic therapy Clinical manifestations of AD include multiple inflamed lesions erosions accompanied by lichenification thick leathery skin fibrotic papules and severely dry skin with increased susceptibility to infection A major uncont ...
STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health -
CardioPort to Enable Intracardiac Beating Heart and Minimally Invasive Open Heart Surgery
SBC: Nido Surgical, Inc Topic: NHLBIDESCRIPTIONprovided by applicantThe goal of this Fast Track STTR project is to develop a novel CardioPortTM surgical device that will enable minimally invasive beating heart repair without use of cardiopulmonary bypassCPBThere is a critical unmet need for new instruments to improve the surgical repair of heart defects in childrenCurrent best surgical practices involve either open heart surgery wit ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
Proteolytic Imaging of Remodeling Myocardium
SBC: Micro Vide, LLC Topic: NHLBIDESCRIPTIONprovided by applicantProteolytic Imaging of Remodeling Myocardium Abstract Heart attacksi emyocardial infarction or MIoccur in more thanmillion patients annuallyAdvances in interventional and pharmacological therapies have dramatically improved survival following the initial MIand patients are often surviving acute MI with more extensive myocardial injuryConsequentlythe number of patien ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health