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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 51 - 60 of 8816 results
  1. Development of Cell Culture Inserts and 3D In Vitro Tissue Models Utilizing Novel Electrospun Scaffolds

    SBC: BIOSURFACES INC            Topic: R

    Tissue culture inserts that utilize film-based microporous membrane scaffolds are key components of in vitro tissue models that are used as alternatives to animal testing. However, insert scaffold technology has not significantly advanced in nearly 30 years. Currently available film-based insert scaffolds are only 2-dimensional (2D), and are excessively rigid compared to natural extracellular matr ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  2. Augmented Reality Platform for Telehealth Rehabilitation

    SBC: ALTEC, INC            Topic: NIA

    Restrictions imposed by the COVID-19 global pandemic have continued to alter the delivery of, and access to, healthcare across the nation. The resulting unmet health needs have had a disproportionate effect among older Americans as they continue to be at the highest mortality risk for the latest variants of COVID-19. Additional health disparities due to race, gender, residential location, and inco ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  3. SmartAssist™: Adaptive robotic assistance to maximize patient engagement with the Barrett Upper-Extremity Robotic Trainer (Burt)

    SBC: BARRETT TECHNOLOGY, LLC            Topic: NICHD

    Project SummaryIn stroke rehabilitation, patient engagement in therapy is critical for improving functional outcomes. Robot- assisted rehabilitation can provide repeatable, high-intensity therapy tailored to the needs of the patient, while also decreasing the load on the therapist. The Barrett Upper-Extremity Robotic Trainer (Burt®), an FDA Class-II medical device developed and sold by Barrett Te ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  4. Time-lapse Flow Cytometry for Kinetic Profiling of T-Cell Function

    SBC: LASE INNOVATION INC            Topic: 102

    Abstract Despite progress in immunotherapies, there are significant challenges to overcome to make them more broadly applicable to different cancers and more effective for patients. However, current efforts to improve adoptive cell therapies and immune checkpoint blockade as well as cancer vaccines are hampered by the lack of a method to characterize the functional and phenotypical changes of diff ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  5. BRITE-Eye: An integrated discovery engine for CNS therapeutic targets driven by high throughput genetic screens, functional readouts in human neurons, and machine learning

    SBC: QUELLTX INC            Topic: 101

    Project Summary Neurological disorders affect millions of patients worldwide and represent a major unmet medical need. Recent progress on developing new classes of central nervous system (CNS) therapeutics has lagged compared to other disease areas. A key obstacle in the CNS drug discovery process has been a need for cellular models, assays, and technologies that can more reliably assess disease-r ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  6. Commercialization of methods and reagents for high-throughput single cell analysis

    SBC: FLUENT BIOSCIENCES INC            Topic: 400

    PROJECT SUMMARY / ABSTRACT Single-cell RNA sequencing (scRNAseq) provides unprecedented insight into the gene regulatory pathways of living cells in complex tissues. Fluent BioSciences has developed Pretemplated Instant Partitioning for single-cell RNA sequencing (PIPseq) that eliminates the cost and complexity of bespoke microfluidics and instrumentation and features a simple, flexible workflow t ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  7. Rapid Point-of-Care Assay for Diagnosis of Neurocysticercosis in Seizure Patients

    SBC: KEPHERA DIAGNOSTICS LLC            Topic: NIAID

    Project Summary Epilepsy, a disorder of the brain manifested by seizures, is the fourth most prevalent neurological disease, affecting over 50 million people worldwide, or about 1 out of 150 individuals on average. The frequency of epilepsy is distributed unevenly, however, with the vast majority of cases occurring in less developed regions of the world. The likely explanation for this distributio ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  8. Manganese-based Contrast Agent for Cardiovascular MRI

    SBC: Reveal Pharmaceuticals, Inc.            Topic: NHLBI

    ABSTRACT Cardiovascular disease is the leading cause of morbidity and death, representing 1 in 3 deaths in the United States, and 18.6 million deaths globally annually. Contrast enhanced magnetic resonance imaging (MRI) and computed tomography (CT) play a key role in managing heart disease by enabling non-invasive assessment of myocardial perfusion, infarction, and viability. Cardiac imaging is th ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  9. SIBTime: Media-enhanced Technology for Promoting the Behavioral Health and Family Relationships of Typically Developing Young Siblings

    SBC: OREGON RESEARCH BEHAVIORAL INTERVENTION STRATEGIES, INC.            Topic: NIMHD

    Project Summary/AbstractIndividuals who have disabilities and health impairments frequently have typically developing (TD) siblings who share high levels of involvement throughout their lifespan. Increasingly, siblings are being recognized by parents, government, and disability service providers as the next generation of caregivers for people with disabilities, yet the risks and stressors they exp ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  10. Fibrogenesis Targeted Manganese Based MRI Contrast Agent

    SBC: Reveal Pharmaceuticals, Inc.            Topic: 300

    Nonalcoholic fatty liver disease (NAFLD) affects an estimated 20-30% of adults in the western world. Most NAFLD is benign, but up to 30% of NAFLD patients will develop a progressive form of fatty liver termed nonalcoholic steatohepatitis (NASH). NASH is the leading cause of severe liver disease, leading to rt$175 billion in healthcare costs over the next two decades in the US, and NASH prevalence ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
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