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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

Displaying 51 - 60 of 3458 results
  1. Use of mimotope vaccine technology to develop vaccines against bacterial pathogens

    SBC: ZenVax LLC            Topic: NIAID

    ABSTRACT This Small Business Technology TransferSTTRPhase I proposal is in response toNIH NIAID Research Topics in Division of Microbiology and Infectious Diseases and Bacteriology and Mycology BranchVaccine for prevention of human Q feverQ fever is a worldwide zoonotic disease that is caused by the obligate intracellular Gram negative bacteriumCoxiella burnetiiThe highly infectious nature of Cbur ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  2. Enhanced x-ray angiography analysis and interpretation using deep learning

    SBC: VIGILANT MEDICAL, INC.            Topic: NHLBI

    Enhanced x ray angiography analysis and interpretation using deep learning OverMillion diagnostic X ray angiograms are performed annually in the US to guide treatment of coronary artery diseaseCADand cost over $billionDespite being the clinical standard of carevisual interpretation is prone to interand intra observer variabilityRecently as part of the NHLBI supported Prospective Multicenter Imagin ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  3. An Improved Robotic Electrophysiology Platform for Arrhythmia Ablation

    SBC: UNandUP, LLC            Topic: NHLBI

    Arrhythmias are due to irregular contractions and disorganized electrical signals within the heart and are a leading cause of death in the United StatesUSVentricular tachycardia and ventricular fibrillation are the most serious arrhythmias and are associated withk annual US deathsIn comparisonatrial fibrillationAFimpactsM Americansmaking it the most common arrhythmiaWith nearlyk annual US hospital ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  4. High Frequency Dielectric Sensing Cardiac Radio Frequency Ablation Monitoring and Lesion Assessment System

    SBC: SIGT, LLC            Topic: NHLBI

    Atrial fibrillationAFibaffects aboutmillion individuals in the USA and is a significant cause of morbidity and mortalityPercutaneous catheter intracardiac Radio Frequency AblationRFAtreatment of AFib requires contiguous transmural lesions between anatomical boundaries for effective durable electrical isolationCurrent procedures have arecurrence rateprobably due to incomplete ablations and carry ar ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  5. "Blueprint of Life" Genomic Literacy Tool: An interactive to enhance genetic and genomic understanding with middle/high school students and their teachers through personal genetics and human disease

    SBC: D'Vinci Interactive, Inc.            Topic: 500

    NIGMS Phase I SBIRBlueprint of LifeGenomic Literacy Interactive Project Summary The increasing prevalence of genetics and genomics in everyday life and in the media calls for a more effective education of students in these fieldsRecent changes in educational systems provide an exciting opportunity to embed more genomics into middle and high school classrooms due to both the interdisciplinary natur ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  6. Inexpensive Add-on Plasmonic Patch to Enable Ultrasensitive and High-Dynamic Range Protein Microarrays

    SBC: Auragent Bioscience, LLC            Topic: NIAID

    AbstractDetection and quantification of various proteins in biological fluids and tissues is of fundamental importance in biomedical research and clinical diagnostics because it is impossible to fully characterize complexnon linearbiochemical systems without being able to accurately and quantitatively interrogate the component moleculesThere is not a commercially available tool that allows researc ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  7. Genetically Modified Conditional Sexing A. stephensi Line for PfSPZ Manufacture

    SBC: SANARIA INC.            Topic: NIAID

    There is an the urgent need for new tools for preventioncontroland elimination of malariaafter an unprecedented period of success in global malaria controlprogress has stalledInthere were an estimatedmillion cases of malariaan increase of aboutmillion cases overDeaths reachedmore than inPlasmodium falciparumPfsporozoitesSPZare the only immunogens that have prevented Pf infection in andgtof human r ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  8. Rapid discovery of thousands of intact biosynthetic gene pathways for bioactive natural product compounds from un-sequenced filamentous fungi using a novel FAC-NGS tool

    SBC: Intact Genomics Inc.            Topic: NIAID

    Project Summary Abstract The goal of this project is to develop a highly rigorous technology platform utilizing lichen and unsequenced fungi to revive the discovery pipeline for fungal derived therapeutics capable of treating chronic infections and health conditionsThe emergence of drug resistant microbesthe diminishing supply of novel classes of antibioticsand the dramatic reduction in discovery ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  9. Online system for identifying and addressing teen depression in primary care

    SBC: Total Child Health, Inc.            Topic: 104

    This proposal presents innovations to addressing teen depression during routine check up visits through further development of an online clinical process support system called CHADISThe primary care provider remains in the center of the process with his her prior relationship with the family and humanity enabled with computer assistance prior to the encounter as well as moment of care reminders an ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  10. An Ultra-fast Cooling Device for Vitrification and Cryopreservation of Cells and Tissues

    SBC: CRYOCRATE LLC            Topic: 100

    Summary The mission of CryoCrate LLCwww CryoCrate comis to develop new platform cryopreservation technologies for applications in life science and clinical practiceWith recent rapid advances in cell based tissue engineering and regenerative medicineas well as continued development of transplantation technologiesthere has always been an urgent need for clinically practical methods and efficient dev ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
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