Award Data

Advances in the fields of real-time computer graphics, behavioral animation and artificial intelligence are enabling creation of realistic 3D Virtual Environments (VE) in which participants can acquire skills that are normally too costly, dangerous orotherwise impossible to achieve using traditional training methods. The effectiveness of such training applications is currently limited when requiri ...

DESCRIPTION (provided by applicant): The overall goal of this proposal is to use animal models to test the efficacy of biglycan as a protein therapeutic for muscular dystrophy. Duchenne's muscular dystrophy (DMD) is a heritable disease that affects approximately 1 in 3,500 boys. These children are usually wheelchair-bound by age 12 and rarely survive past their early twenties. There are currently ...

DESCRIPTION (provided by applicant): The focus of this Phase I proposal is to assess the feasibility of applying our platform of cellular biochemical stabilization with unique freezing and drying engineering design to the goal of generating freeze-dried therapeutic cells. Specifically, this program will target application of ThromboSol, a patented platelet stabilization formula, to the process of ...

In this project, we propose a new detection technology for identification of oligonucleotides, which works by detecting a bio-electronic response from hybridized duplexes. Compared with the conventional approach of using dye tagged oligos, the proposed electrochemical detector has significant advantages. Electrochemical sensing can be implemented using relatively simple equipment. Analysis can be ...

70798B02-II This project will develop a novel, enzyme-catalyzed liquid membrane reactor to separate carbon dioxide from flue gas. The approach involves new reactor design, computer modeling, reaction kinetics testing, and reactor throughput measurement under simulated conditions. Phase I built and evaluated several new reactor designs, initiated computer modeling of the chemistry, and began t ...

70798B02-II This project will develop a novel, enzyme-catalyzed liquid membrane reactor to separate carbon dioxide from flue gas. The approach involves new reactor design, computer modeling, reaction kinetics testing, and reactor throughput measurement under simulated conditions. Phase I built and evaluated several new reactor designs, initiated computer modeling of the chemistry, and began t ...

NON-TECHNICAL SUMMARY: Nostoc commune is an edible cyanobacterium forming the spherical macrocolony, which is used as a potent herbal medicine and dietary supplement. Due to its nutraceutical and pharmacological value, the N. commune has received increasing attention, and the market demand has grown drastically during the last decade. However, low yield and unstable quality caused by inadequate pr ...

Short ammunition-feed swing chambers and efficient on-vehicle ammunition storage, consistent with Cased Telescoped Ammunition (CTA), will facilitate the Army's Force Transformation, through lighter vehicles required by the Future Combat Systems (FCS)program for the Objective Force. Sealing of propellant gases hampers application of CTA. Phase I Modeling and Simulation Studies (design, analysis, ...

Bipolar Junction Transistors (BJT) are used for power and mixed signal applications in radiation environments. Current BJT devices perform with volatile operation requiring constant power supply for uninterrupted access. We propose to create a nonvolatileBJT memoy device using proprietary SMI cerium based ferroelctric mterial (patent pending) prodced by Metal Organic Chemical Vapor Deposition (MOC ...

72164S03-I Plasma instabilities are a key factor limiting the performance of fusion devices, and the identification and understanding of these instabilities will be required before fusion can be an economically attractive energy source. To help in the identification and characterization of the instabilities, this project will develop technology for high-frequency, high-spatial-resolution measure ...