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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Translating an In-Person Brief, Bystander Bullying Intervention (STAC) to a Technology-Based

    SBC: KLEIN BUENDEL, INC.            Topic: 102

    Project Summary While studies support the efficacy of comprehensiveschool wide interventions in reducing bullyingthese types of programs can require significant time and financial resources for implementationresulting in barriers to providing school based bullying preventionespecially in low income and rural communitiesAdditionallyalthough training bystanders to act asdefenderson behalf of targets ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  2. Discovery of Zika virus therapeutics using a replicon assay

    SBC: MICROBIOTIX, INC.            Topic: R

    ABSTRACT The Zika virusZIKVis the cause of an explosive pandemic of infections across South and Central Americathe Caribbeanand the southeastern region of the United StatesZIKV is a flavivirusa family of small positive strand RNA viruses that includes Dengue virusDENVWest Nile virusWNVYellow fever virusYFVand hepatitis C virusHCVZIKV is transmitted to humans by mosquitoes of the Aedes genusFor the ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  3. A Novel remedy for periodontal bone loss

    SBC: PERIOMICS CARE LLC            Topic: NIDCR

    Abstract Periodontitis is a common chronic inflammatory disease characterized by destruction of the supporting structures of the teeththe periodontal ligament and alveolar boneThe total prevalence of periodontitis in adults agedyears and older wasrepresenting aboutmillion adults agedyears and olderandin adults agedyears and older in the U SEpidemiological data confirm that diabetes is a major risk ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  4. Development of a Wearable Fluorescence Imaging Device for Intraoperative Identification of Brain Tumors

    SBC: BIOPTICS TECHNOLOGY LLC            Topic: 102

    ABSTRACTApproximatelypeople in the United States have been diagnosed with a primary brain tumorOf thesemalignant gliomasMGsaccount for approximatelyof all intracranial tumorswith an overall patient survival rate of onlyMore than any other cancerbrain cancer has lasting physicalcognitiveand psychological impacts on a patient s lifeand the highest per patient initial cost of careSurgical resection r ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  5. A New Non-Invasive Approach for Accessing Pulmonary Arterial Stiffness in Patients with Pulmonary Hypertension

    SBC: ARCUS-MED LLC            Topic: NHLBI

    Pulmonary hypertensionPHis a disease affecting approximatelyof the general population that is characterized by abnormally elevated mean pulmonary artery pressuremPAPand pulmonary vascular resistancePVRIf left untreatedPH can ultimately lead to right heart failure and deathCurrent diagnostic approaches utilize invasive right heart catheterizationRHCto measure mPAP and PVREarly detection of PH leads ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  6. Automated CRISPR Screening Using the CellRaft Technology

    SBC: CELL MICROSYSTEMS INC            Topic: 400

    Project SummaryGenome wide functional genetics has been recently made possible by pooled library based CRISPR Casgene editing technologyBy randomly knocking out thousands of geneslarge scale screens can be conducted for functional geneticsdrug sensitivity and other phenotypesCurrently howeverthis forward genetic approach is largely relegated to live dead screens in mammalian cellsImproving the sop ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  7. A universal mechanobiology tool for drug discovery in lung diseases

    SBC: Mechanobiologix L.L.C.            Topic: NHLBI

    Abstract Despite significant effortsno cure exists for the major respiratory diseases such as asthmaemphysema and pulmonary fibrosis due to a lack of proper preclinical methodsDrug development is often carried out in cultured cellsWhile amenable to imaging and manipulationthis approach lacks the native tissue environment and neglects the effects of mechanical forces due to breathing which influenc ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  8. Unbiased longitudinal neuromorphometry for clinical decision support

    SBC: CORTICOMETRICS LLC            Topic: NIA

    Project Summary Normal human neuroanatomy is incredibly variableand increases with ageThis impedes the ability of neuroimaging to detect effects in neurological conditions such as Alzheimerandapos s diseaseADHuntingtonandapos s diseaseHDmultiple sclerosisMSand schizophreniaMost of the recently available state of the art quantitative imaging tools still use cross sectional methods to analyze repeat ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  9. Smartphone-based rewards as a bridge to treatment for naloxone reversal patients

    SBC: DYNAMICARE HEALTH INC            Topic: NIDA

    ABSTRACT Opioid overdose is a major public health crisisand a clear sign of problem drug useMany people who experience an overdose receive a naloxone reversal and are treated in a hospital emergency departmentHoweverfew overdose survivors enroll in treatmenteven if they receive care and referral to treatment while in an emergency departmentMedication assisted treatmentsMATsuch as methadone or bupr ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  10. Development of a Designer Proline-rich antimicrobial peptide Chaperone protein inhibitor (DPC) for treating multi-drug resistant urinary tract infections

    SBC: Arrevus, Inc.            Topic: NIAID

    Urinary tract infectionsUTIsare one of the most common hospital acquired infections and are often caused by multi drug resistantMDRbacterial pathogensMDR bacterial pathogens are associated with significant morbidity and mortalitycreating enormous healthcare and economic burdens due to variations in disease natural histories as well as the lack of effective therapeutic optionsTreatment option limit ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
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