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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Ultra-sensitive Rapid Diagnostic Test to Support the End-Game of the Global Program to Eliminate Lymphatic Filariasis
SBC: NANOCOMPOSIX, INC. Topic: NIAIDProject SummaryAbstract Lymphatic filariasisLFcaused by the parasitic filarial worm Wuchereria bancroftiis a disfiguring and debilitating neglected tropical disease that affectsmillion people incountriesThrough the World Health Organization sWHOGlobal Program for the Elimination of Lymphatic FilariasisGPELFbillion drug regimens have been distributed via mass drug administrationMDAtomillion people ...
STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
Measuring toxicant effects on cellular function in a microarray format
SBC: CIENCIA INC Topic: 113Project Summary/Abstract – The EPA maintains a Toxics Release Inventory of andgt;650 toxic chemicals that are disposed or released from andgt;20,000 industrial sites in the United States, while HHS and USDA maintain a list of over 60 select agents and toxicants that pose a severe risk to human, animal, and plant health. These compounds represent only a fraction of the known and unknown environme ...
STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health -
Discovery of alpha4beta2 Nicotinic Receptor Antagonists as Alcohol Abuse Medications
SBC: ASSUAGE PHARMACEUTICALS, INC. Topic: NIAAAPROJECT SUMMARY Alcohol addiction and disorders associated to excessive alcohol use are a serious public health problem in the United States and in other parts of the world Current pharmacotherapies for the treatment of these disorders show limited efficacy Preclinical and clinical findings point to nicotinic acetylcholine receptors nAChRs as an alternative promising target for the developmen ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
Maximizing cancer synthetic lethality using dual PI-3K/PARP inhibitors
SBC: SignalRx Pharmaceuticals Inc. Topic: NCIPARP inhibitors PARPi are particularly efficacious in tumors deficient in the BRCA tumor suppressor genes but of limited activity in BRCA competent tumors There is an unmet medical need to develop targeted therapeutic agents which will augment PARPi activity for BRCA wild type cancers and to increase chemo radiosensitivity in these malignancies BRCA proteins are essential components ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
Whole Brain Nanoscale Preservation Imaging
SBC: Nectome Inc. Topic: 101Abstract Summary Nectome will create technologies to enable whole brain nanoscale preservation and imaging a vital step towards a deep understanding of the mind and of the brainandapos s diseases Current brain processing technologies compromise between whole brain applicability or nanoscale resolution our technologies will achieve both si multaneously Similar to the way that next generation ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
Product Development of Intensity Modulation for Bolus Electron Conformal Therapy
SBC: Decimal, LLC Topic: 102Project Summary Abstract Electron beam therapy EBT using MeV beams provides effective radiation treatment for superficial cancers depthandlt cm As many as of radiotherapy patients in USA annually are eligible for electron therapy for some portion of their treatment making it the second most used external beam modality As many as of these electron patients ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
Identifying activators of interferon regulatory factors for neuroprotection
SBC: Neuralexo, LLC Topic: 106Abstract Stroke is a leading cause of morbidity and mortality in the United States However less than of patients are eligible for the current approved interventions of tissue plasminogen activator or thrombectomy We seek to develop new therapeutics to reduce the extent of damage and functional impairment resulting from ischemic injury to the brain an area of significant unmet medical need ...
STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health -
Superhydrophobic Implantable Surface and D Printing Technology for Targeted Dental Photodynamic Therapy
SBC: SINGLETO2 THERAPEUTICS LLC Topic: 100Project Summary Abstract Eradication of bacteria that are located in periodontal pockets is a daunting challenge to dentists and oral care professionals Doxycycline or minocycline with scaling and root planing Sandamp RP have been the mainstays but the field urgently needs further advances in perio bacteria eradication A high precision photochemical implement that could be used simultaneousl ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
An Agent-Based Modeling Platform for Environmental Biotechnology
SBC: MICROVI BIOTECH, INC. Topic: NIEHSDESCRIPTION provided by applicant Hazardous compounds in waters and soils are subject to a complex dynamic web of interactions among physical chemical and biological constituents in the natural environment Computational modeling has been proven indispensable to hazardous substances remediation particularly integrated modeling of pollutant hydrogeological fate and transport For the first t ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
Enhancing Care of the Aged and Dying in Prisons
SBC: KLEIN BUENDEL, INC. Topic: NIAThe United States has the highest rate of incarceration in the world There are over state and federal prisons housing over million prisoners in the United States The demographics of the prison population are shifting Longer sentences and constrained options for early release compound this trend The older adult segment of prison populations has more than tripled since The health ...
STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health