Award Data

Frog Embryo Teratogenesis Assay: Xenopus (FETAX) is a 96-h, whole-embryo bioassay designed to detect potential developmental toxicants. The primary goal of this research is to improve the predictability and increase the overall utility of FETAX as a screen for developmental toxicants that pose a hazard to human health. Since Xenopus laevis embryos lack mixed-fliriction oxidase metabolism (cytoch ...

The proposed Phase I project is the design and development of a wireless comprehensive sensor system for structural health assessment and monitoring. The final goal will be a system consisting of sensor modules or packages which can be permanently placed at the selected critical locations within a structure and which are powered and communicate wirelessly with a master station. The sensor module ...

Systems & Processes Engineering Corporation (SPEC) proposes to develop a Waveform Agile Signal Processor (WASP) to support the next generation of fuzing systems and subsystems. WASP is designed to~provide high performance, waveform agile, adaptive signal processing for a variety of RF and optical fuze sensors. WASP is designed to support pulsed time domain, frequency domain, phase, direct sequen ...

Optimization of antibody affinity and specificity is of paramount importance to the military for the development of biological warfare agent receptors and vaccine components. Exhaustive saturation mutagenesis of the complete antigen binding site for such optimization must typically involve the construction and characterization of several hundred mutants. Using conventional mutagenesis, the expen ...

One of the most serious obstacles to the practical implementation of biosensor technology for BW and CW detection onto UAV 5 and other remote deployment applications is the need for miniaturization of the sensor systems. To meet this need, Systems & Processes Engineering Corporation (SPEC) proposes to develop a miniaturized biosensor system which is essentially reagentless. The proposed system w ...

Biological Warfare (BW) agents, delivered as an aerosol, are a serious and growing threat. The detection of a sudden and significant increase in biological substances in the air would be sufficient to indicate a high probability of BW release and allow protective actions to be taken. Systems & Processes Engineering Corporation (SPEC) and Prof. Richard Chang of the Dept. of Applied Physics at Yal ...

Optical techniques employing photoluminescent pressure-sensitive paints provide versatile tools for obtaining pressure maps of the aerodynamic surface. These techniques do not distort the flow field like arrays of pressure transducers or pressure taps on the test surface, and they provide high spatial resolution, accuracy and rapid response. Current techniques based on the fluorescence intensity ...

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Tactical wheeled vehicles represent a prominent portion of the Army's budget for both acquisition and operating costs. TACOM has identified suspension lubrication as a mission critical area for improvement. The goal is to lubricate a vehicle's suspension continuously for two years. This should create a cascade of cost effects in both maintainability and reliability. Single-point lubricators ba ...

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