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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Preventing Neurovascular Matrix Degradation and Hemorrhage in Acute Ischemic Stroke

    SBC: TRANSLATIONAL SCIENCES INC            Topic: NHLBI

    Seventeen million people each year suffer from an ischemic stroke and millions are left dead and disabledTreatment with recombinant tissue plasminogen activatorr tPAis only modestly effective at reducing disability and it is associated with brain hemorrhage in up toof patients when serial imaging studies are performedBrain hemorrhage causes death and disability andis the major cause of early morta ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  2. Fully Human Antibodies for the Prevention of Respiratory Syncytial Virus

    SBC: IDBIOLOGICS INC            Topic: NIAID

    The goal of this STTR is to provide a preclinically validated monoclonal antibody or antibody combination for the prevention of respiratory syncytial virusRSVin high risk patients including infants and the elderlyWorldwideof children are infected with RSV before the age ofresulting in an estimatedmillion lower respiratory tract infectionsIn the United States adults overhavemillion RSV infections c ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  3. Long non-coding RNA signatures to track treatment responses in multiple sclerosis

    SBC: IQuity Labs, Inc.            Topic: NIAID

    ABSTRACTEarly detection of multiple sclerosis is key to limiting neurological damage but monitoring patient progression and response to therapy is of arguably similar if not greater importance due to the chronic nature of diseaseMoreoverrates of non adherence to therapy has been reported to be as high astoin the patient population suggesting the need to provide continuous monitoring and selection ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  4. Engineered enzyme sensors based on allosteric regulation

    SBC: Pharmaseq, Inc            Topic: 400

    Summary It is proposed to develop an approach for constructing enzyme based sensors for detecting biomoleculesThe sensor is an enzyme modified by site directed mutagenesis to create a binding site specific for a target biomoleculeA library of engineered enzyme sensors is constructed to serve as a repository of potential bindersThe binding site is positioned in the immediate vicinity of the enzymea ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  5. Spring-Powered Exosuit to Prevent Low Back Pain due to Overuse Injury

    SBC: HEROWEAR LLC            Topic: NIOSH

    TBD

    SBIR Phase I 2019 Department of Health and Human ServicesCenters for Disease Control and Prevention
  6. A SELF-REGULATING PUMP CHAMBER FOR STANDARD ROLLER PUMPS

    SBC: Adam Spence Corpon            Topic: N/A

    THE ROLLER PUMP, USED TO PUMP BLOOD FLOW DURING CARDIOPULMONARY BYPASS AND TO PROVIDE LONG-TERM CIRCULATORY SUPPORT, IS A CONSTANT-BLOOD-FLOW DEVICE. IT MAINTAINS CONSTANT FLOW INDEPENTLY OF THE CLINICALLY EXPECTED CHANGES IN INLET PRESSURES. A DECREASE IN BLOOD SUPPLY TO THE INLET OF THE PUMP WITHOUT A CONCOMITANT DECREASE IN PUMP SPEED CAN CAUSE EXCESSIVE SUCTION LEADING TO AIR EMBOLISM, THROMBO ...

    SBIR Phase I 1987 Department of Health and Human Services
  7. NEONATAL NUTRITION AND RESONANCE IONIZATION SPECTROSCOPY

    SBC: ATOM SCIENCES, INC.            Topic: N/A

    A PAUCITY OF KNOWLEDGE EXISTS ABOUT NEONATAL TRACE ELEMENT NUTRITION REQUIREMENTS, ESPECIALLY FOR PREMATURE INFANTS, WHOSE CRITICAL FINAL TRIMESTER ACCUMULATION OF ESSENTIAL TRACE ELEMENTS IS ABRUPTLY CEASED AT BIRTH. THE OBJECTIVE OF THIS PROPOSAL IS TO DEVELOP THE SCIENCE AND TECHNOLOGY "BRIDGE" REQUIRED TO DEMONSTRATE THE FEASIBILITY OF DIRECT, OR NEARLY DIRECT, DETERMINATION BY RESONANCE IONIZ ...

    SBIR Phase II 1987 Department of Health and Human Services
  8. TRACE CHROMIUM IN DIABETES USING RESONANCE IONIZATION

    SBC: ATOM SCIENCES, INC.            Topic: N/A

    TRACE ELEMENT NUTRITURE IS INCREASINGLY ACKNOWLEDGED AS A KEY ASPECT OF GROWTH, DEVELOPMENT, AND HEALTH. TRACE CHROMIUM MAY BE RELATED TO REGULATION OF INSULATION ACTION, RESTORATION OF IMPAIRED GLUCOSE TOLERANCE, AND THE CAUSAL

    SBIR Phase I 1987 Department of Health and Human Services
  9. IMAGING OF ELEMENTS IN TISSUE AT TRACE CONCENTRATIONS

    SBC: ATOM SCIENCES, INC.            Topic: N/A

    INSTRUMENTATION ENABLING QUANTITATIVE TRACE ELEMENT-CONCENTRATION IMAGING WITH HIGH SENSITIVITY AND RESOLUTION (1 PPM, 5 ) OF BIOLOGICAL TISSUE SECTIONS OVER 2X2MM(2) WOULD BE A VALUABLE RESEARCH TOOL. SIMULTANEOUS STRUCTURAL IMAGING WOULD ENHANCE ITS UTILITY. SPUTTER-INITIATED RESONANCE IONIZATION SPECTROSCOPY (SIRIS) WILL BE ADAPTED TO PROVIDE STRUCTURAL IMAGING AND QUANTITATIVE ELEMENT-CONCENTR ...

    SBIR Phase I 1987 Department of Health and Human Services
  10. SUBPICOSECOND DESORPTION AND MASS ANALYSIS OF LARGE MOLECULES

    SBC: ATOM SCIENCES, INC.            Topic: N/A

    EMERGING HEALTH AND MEDICAL RESEARCH PROBLEMS ARE PLACING STRINGENT REQUIREMENTS ON THE ABILITY TO CHARACTERIZE LABILEAND HIGH-MOLECULAR-WEIGHT ORGANIC COMPOUNDS. IN BIOTECHNOLOGY, FOR EXAMPLE, INTERMEDIATE SYNTHESIS PRODUCTS MUST BE IDENTIFIED. RECENT ION BOMBARDMENT DESORPTION MODELS SUGGEST THAT HIGHEST-MOLECULAR-WEIGHT COMPOUNDS WOULDDESORB MOST EFFICIENTLY THROUGH RAPID, MULTIPLE EXCITATIONS ...

    SBIR Phase I 1987 Department of Health and Human Services
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