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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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A small molecule broad spectrum inhibitor of antiapoptotic genes to treat cancer
SBC: CANGET BIOTEKPHARMA, LLC Topic: 102Abstract The goal of this fast track SBIR proposal is to file an investigational new drugINDapplication for testing a novel anticancer drugFLthat is designed to overcome inherent and acquired treatment resistanceMany types of cancers are not detected until they are very advanced and have already become resistant to FDA approved treatmentsIn additionmany non advanced cancers respond well to initial ...
SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health -
Overcoming Appointment Adherence Barriers Using Social Support
SBC: Transcendent International, LLC Topic: 102DESCRIPTION provided by applicant Appointment non attendance or andquot no showsandquot is common across health institutions hindering efficient functioning of healthcare systems and contributing to over $ billion in annual costs Further appointment non attendance is associated with poorer health outcomes as patients forgo critical preventative care and fail to receive necessary t ...
SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Small Molecules To Inhibit PCSK9-LDLR
SBC: Small Molecule PPI Mimics LLC Topic: NHLBIDESCRIPTION provided by applicant This proposal is to prepare small molecules that will inhibit the protein protein interaction between a protein called PCSK and the LDLR receptor This is an extremely well validated target for reduction of andquot badandquot cholesterol LDL and therefore controlling coronary artery disease Orally available small molecules are the preferred therapeutic mo ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Mass Spectrometric Screening of the Effect of Chemical Toxicants on the Human Epitranscriptome during Stem Cell Differentiation
SBC: ATHGHIN BIOTECHNOLOGY, INC. Topic: 113DESCRIPTION provided by applicant Epitranscriptomics explores levels and evolution of RNA modifications as a response from intra and inter cellular stimuli These modifications and the levels at which they are present are emerging as important regulators of biological processes Perturbations such as chemical toxicants exposure can alter the patterns of specific modifications on RNA sub types ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
The Development of a High-Throughput Assay to Screen Chemical Compounds in Human Pluripotent Stem Cell Derived Neural Cells
SBC: ATHGHIN BIOTECHNOLOGY, INC. Topic: 113DESCRIPTION provided by applicant The long term objective of this application is to provide a high throughput platform to test the effects of chemical exposure on human brain development In the US chemicals are not required for health or environmental safety testing before their incorporation in consumer products Over registered chemicals are in commerce most of which are used withou ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Distance Filtering System for Retinal Implants
SBC: ADVANCED MEDICAL ELECTRONICS CORP Topic: NDESCRIPTION provided by applicant We propose to develop and evaluate the utility of a novel input camera system for retinal prosthetics that allows users to filter optical imagery based on distance from the observer We call this andquot depth filteringandquot which can be accomplished with a depth sensing stereoscopic camera system Retinal prostheses can restore partial vision to people bli ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Advanced Nitric Oxide Release Bactericidal Urinary Catheters
SBC: BIOCREDE INC. Topic: 300DESCRIPTION provided by applicant In Phase I Biocrede developed a completely new urinary tract silicone Foley catheter with a andgt month shelf life made from a proprietary polymeric formulation to effectively reduce catheter associated urinary tract infections CAUTI via nitric oxide NO release for andgt weeks Key features of the new technology include catheters continuously d ...
STTR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health -
Development of a Minimally Invasive Surgical Device for the Treatment of Esophageal Cancer
SBC: CELL PRESERVATION SERVICES INC Topic: NCIDESCRIPTION provided by applicant The treatment of Esophageal Cancer has experienced a palpable increase in the last few years While numerous options are currently under investigation many if not all remain suboptimal This is critical as it is estimated that in there were new cases and over deaths from esophageal cancer worldwide In the US alone there were new ...
SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Continuously Load-Sharing Elastically Deformable Spinal Fusion Implant
SBC: ReVivo Medical, LLC Topic: NIAMSDESCRIPTION provided by applicant ReVivo Medical LLC has developed the next generation of spinal fusion implants to help surgeons and hospitals achieve the goals of the Affordable Care Act ReVivoandapos s spinal implants are the first to leverage the basic science of bone formation to reduce time to fusion while also diminishing complication rates decreasing operating room time and loweri ...
SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Clinical utility of serum biomarkers for the management of neonatal Hypoxic Ischemic Encephalopathy (HIE) on a point-of-care device
SBC: BANYAN BIOMARKERS, INC. Topic: NICHDDESCRIPTION provided by applicant Systemic asphyxia occurs in of births and can lead to hypoxic ischemic encephalopathy HIE Between and of neonates with HIE die or have permanent deficits Although hypothermia is the standard of care for HIE we cannot differentiate patients who respond to hypothermia from non responders The primary goal of this project is to conduct a proof ...
SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health