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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 51 - 60 of 207728 results
  1. A2A receptor blockade for sepsis

    SBC: Purine Pharmaceuticals Inc.            Topic: NIAID

    SUMMARY Sepsis is a clinical syndrome that complicates severe infectionSepsis remains the leading cause of morbidity and mortality in critically ill patientsThere are no specific FDA approved medicines for the treatment of sepsisCurrent concepts of the pathophysiology of sepsis suggest that organ failure and mortality in sepsis are caused by inappropriate regulation of the immune systemThis manife ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  2. AARS: A System Solution to Autonomous Aerial Refueling of Powered Munitions

    SBC: StarVision Technologies, Inc.            Topic: AF05165

    StarVision Technologies proposes to conduct an experimental feasibility assessment of an innovative and robust Autonomous Aerial Refueling System (AARS). The system has been developed specifically for powered munitions and will provide significant battlefield enhancements by allowing persistent and sustained air operations. The AARS proposed is the result of several years of studies and feasibili ...

    SBIR Phase I 2005 Department of DefenseAir Force
  3. AARS: A System Solution to Autonomous Aerial Refueling of Powered Munitions

    SBC: StarVision Technologies, Inc.            Topic: AF05165

    Autonomous Aerial Refueling (AAR) of powered munitions can enable persistent loitering and provide significant benefits to future warfighters. The technology has immediate commercial applications and the feasibility of AAR for small unmanned vehicles has been successfully demonstrated in the Phase I project. A total system solution to AAR has been conceived that includes a precision relative nav ...

    SBIR Phase II 2006 Department of DefenseAir Force
  4. 15a. Augmented Intelligence for Microscopy Informatics

    SBC: INTELLISENSE SYSTEMS INC            Topic: C5315a

    The emergence of big data gathering experiments in microscopy has created new challenges in maintaining standards for scientific integrity and reproducibility. The diversity of data, available microscope modalities, and larger number of collaborators increase the complexity of scientific asset management for evolving experiments. Recently developed scientific asset management software addresses th ...

    SBIR Phase I 2022 Department of Energy
  5. 20a. Automated Data Collection and Compression System for CO2 Monitoring Data

    SBC: Teverra LLC            Topic: 20a

    Over the past two decades, there has been a drastic advance in the sensing technologies and data acquisition systems. These technologies have been deployed in carbon sequestration to continuously monitor CO2 migration and location during and after injection. A complex network of surface and underground sensors is often installed generating large volume of intricate datasets. These datasets require ...

    SBIR Phase I 2019 Department of Energy
  6. 25/a Autonomous Monitoring of Low Phosphate Concentrations at TAIs

    SBC: LEIDEN MEASUREMENT TECHNOLOGY LLC            Topic: C5325a

    Although phosphate is a critical nutrient involved in estuarine productivity, it is also a well-known contaminant of surface and ground water. This contamination can have significant effects in sensitive areas such as the terrestrial aquatic interfaces (TAIs) where the flux of nutrients can change over a relatively short period of time leading to hypoxia and the formation of harmful algal blooms. ...

    SBIR Phase I 2022 Department of Energy
  7. AAV-AIBP Therapy for Alzheimer's Disease

    SBC: RAFT PHARMACEUTICALS LLC            Topic: NIA

    PROJECT SUMMARY Therapy for Alzheimer’s disease and related dementias (AD/ADRD), slow-progressing neurodegenerative diseases, remains elusive. Therapeutic approaches focusing on beta amyloid (Aβ) removal from the brain or on targeting genes for which strong associations between their polymorphism and AD/ADRD are established, have had a mixed record of success. We propose a novel strategy to rev ...

    STTR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  8. AAV2-ASPA-Based Metabolic Intervention for Alzheimer's Disease

    SBC: ASKLEPIOS BIOPHARMACEUTICAL, INC.            Topic: NIA

    Abstract We propose to initiate preclinical development of a gene therapeutic targeted to Alzheimer's Disease. The World Health Organization's and Alzheimer's Disease International's report on Dementia (2012) recognizes that the global burden of AlzheimerDisease is forecast to worsen significantly with prevalence predicted to double every 20 years. Interventions that could prov ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  9. AAV-based toolkit for targeting specific cell types

    SBC: NEUROTARGETING SYSTEMS            Topic: NINDS

    DESCRIPTION (provided by applicant): Our goal is to develop an efficient and inexpensive toolkit for ablating or reversibly inactivating specific cell types in the brain or other organs of mammals. We propose new techniques in which the genes for nitroreductase (NTR) or Drosophila allatostatin receptor (AlstR) are delivered into cells using an adeno-associated viral vector (AAV). Both are fusion ...

    SBIR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  10. AAV Benchmark

    SBC: Vectraxx, Inc.            Topic: N111016

    The term benchmark originates from the chiseled horizontal marks that surveyors made, into which an angle-iron could be placed to bracket ("bench") a leveling rod, thus ensuring that the leveling rod can be repositioned in exactly the same place in the future. A benchmark in computer terms is the result of running a computer program, or a set of programs, in order to assess the relative performanc ...

    SBIR Phase I 2011 Department of DefenseNavy
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