Award Data

There is an urgent need to rapidly test warfighters and their surrounding environment for disease-causing pathogens such as SARS-CoV-2. Existing methods for identifying pathogens in people usually require significant time and sample preparation. In addition, detecting pathogens such as SARS-CoV-2 in the air presents an even greater challenge. To meet the DoD need for field portable bioaerosol iden ...

Rapid, real-time bioaerosol identification is a key aspect in preventive measures for infectious disease outbreaks, e.g. SARS-CoV-2 or tuberculosis. Current screening tools are either non-specific, or are slow, costly, and reagent burdened. As with most respiratory pathogens, such diseases are primarily spread through human discharge of pathogen-containing droplets created by coughing, sneezing or ...

Recent efforts to improve treatment for nerve agent poisoning include the development of a scopolamine hydrobromide injectable as an anticholinergic. A scopolamine injectable would add an extremely beneficial capability to the warfighter kit, however, incorporation of single-use vials represents a substantial logistical burden in the field. Co-formulation of the scopolamine injectable with a suita ...

The Joint Project Manager for Chemical, Biological, Radiological, and Nuclear Medical is developing scopolamine hydrobromide trihydrate (Scop-HBT) under the Improved Nerve Agent Treatment System - Centrally Acting program. Scop-HBT is an anticholinergic medical countermeasure that temporarily blocks severe or life-threatening muscarinic effects caused by organophosphorus nerve agent (OPNA) poisoni ...

To meet CBD’s need for a multi-dose formulation of scopolamine hydrobromide trihydrite ChromoLogic proposes to develop a vial add-on containing a self-decontamination cap with a self-healing material to eliminate evaporation and contamination risks through needle punctures in the septum. CL will also perform forced degradation and stability tests with a panel of preservatives to select optimal p ...

The Joint Project Manager for Chemical, Biological, Radiological, and Nuclear Medical (JPM CBRN Medical) seeks to develop dermal dressing technologies that provide multiple advantages over current wound dressings for treating dermal injuries caused by sulfur mustard. Critical Innovations, Battelle's Biomedical Research Center, and NDA Partners, with consultants Captain David Tanen, MD, FAAEM, FACM ...

Field Shield Wound Dressing (FSWD) is a novel wound dressing that takes an innovative approach to addressing major wounds, both in prolonged field care and throughout the continuum of care. It is the first wound dressing to combine an effective broad spectrum antimicrobial (nanosilver) with a local anesthetic (lidocaine) in a simple to apply point-and-spray wound dressing. A patented polyacrylate ...

Fabrico Technology, Professor Kevin Dalby, the Johnson & Johnson Centennial Professor of Chemical Biology & Medicinal Chemistry, and Dr. Tamer Kaoud, Research Assistant Professor of Chemical Biology & Medicinal Chemistry, College of Pharmacy, the University of Texas at Austin (UT), propose to develop and discover a new family of a small molecule(s) that increases the endosomal pH resulting in inhi ...

Aptamers are oligonucleotides that bind like antibodies to envelope and other viral proteins to block or inhibit viral host cell entry and replication for passive immunity until a patient can mount an effective immune response. In Phase I, Nanohmics proposes to test existing DNA aptamers against Crimean Congo Hemorrhagic Fever envelope epitopes funded by a previous SBIR Phase II contract W81XWH-09 ...

Raman spectroscopy has proven to be a reliable field deployable detection technique for assessing chemical threats, including chemical warfare agents, energetic materials, and illicit narcotics. Military and Homeland Security agencies commonly utilize various portable Raman systems in sensitive site exploitation, checkpoint scenarios, and to determine hazardous content on surfaces or containers. E ...