Award Data

DESCRIPTION (provided by applicant): Vical Inc. seeks SBIR Phase II funding to develop and produce a licensable prophylactic anthrax vaccine. This project will move on an accelerated but realistic timeline with plans for human clinical trials to begin in September 2003. Although many candidate vaccines are being studied for anthrax prevention or post-exposure prophylaxis, the Vical approach has ...

Side channel analysis (SCA) and fault injection (FI) are a solid part of the relevant attack space for any chip that can be physically reached by an attacker. These hardware attacks allow key extraction from cryptographic implementations, and fault injection specifically allows complete takeover of devices. Current commercial chip design tools do not offer integrated analysis to verify resistance ...

Blood-based point-of-care (POC) diagnostics or remote diagnostics that require specialized equipment only available in centralized, commercial laboratories are currently limited by major logistical and technical barriers. Blood collection can be a traumatic, inconvenient, and inconsistent process that is based on decades-old technologies, such as the lancet-puncture, that are not amenable to new P ...

Project Summary Sanfilippo disease (mucopolysaccharidosis type III; MPS III) is a devastating neurodegenerative lysosomal storage disorder of childhood whose pathologic features are neurologic: slowing of development, severe behavioral problems, progressive cognitive decline, dementia, and decline in motor skills leading to immobility, unresponsiveness, and death. We have focused on MPS IIID cause ...

Navy’s digital modular radios (DMRs) have been upgraded to support a wide range of waveforms (e.g. SRW, HAVE QUICK, SINCGARS, SATCOM, and MUOS). To further increase the fleet’s warfighting capability, the U.S. Navy is interested in reducing the number of single function RF systems required on Navy ships and submarines. EMBARC (Efficient Multi-carrier Broadband Amplifier for Radio Communication ...

The operational need for this improved towed array technology insertion initiative stems from the necessity to improve availability and reliability of towed arrays in use on submarines in both shallow and deep water environments, and represents a critical submarine capability enhancement. The proposed project will extend and transition the telemetry, packaging and iPEN technologies developed und ...

Abstract DESCRIPTION. In this SBIR FastTrack proposal, Micro-Leads will develop HD64—a high-resolution, 64- channel spinal cord stimulation therapy to provide more pain relief with greater specificity for those suffering from chronic neuropathic pain and opioid dependence. Over 25 million in the U.S. suffer from debilitating pain in the trunk and extremities and 55% depend on opioids to ease the ...

DESCRIPTION (provided by applicant): The overall goal of this project is to develop broad-spectrum antibiotics against Yersinia pestis and other important human pathogens. The potential use of engineered, multi-drug-resistant strains as agents of bioterrorism necessitates the development of new anti-Y. pestis therapies. This is a challenging goal, since the last novel class of broad-spectrum antib ...

There is a need to complement the current Gen III image intensifier imaging system with a solid-state low light level camera that is better optimized for remote viewing applications. A silicon-based solution is an ideal candidate for low light imaging because of its high quantum efficiency, low dark current, and excellent uniformity. However, to meet performance requirements under overcast starl ...

Inovati to proposes to train Air Force staff on operation of the prototype Kinetic Metallization System (KMS) equipment delivered and installed at WPAFB with prototype software for repairing F-16 wheels and A-10 NLG pistons and other aircraft components enabled by deployment of a robot with extended axis capabilities integrated with the KMS equipment. The objective of this project to deliver a pro ...