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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

Displaying 50271 - 50280 of 173942 results
  1. Anti-Autolysin Passive Immunity for MRSA Osteomyelitis

    SBC: CODEVAX, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): Recently methicillin resistant Staphylococcus aureus (MRSA) has surpased HIV as the most deadly pathogen in the United States, accounting for over 100,000 deaths per year. In Orthopaedics, MRSA osteomyelitis (OM) has become the greatest concern in patient care, desite the fact that improvements in surgical technique and aggressive antibiotic prophylaxis have d ...

    SBIR Phase I 2010 Department of Health and Human Services
  2. Substance Abuse Continuing Care through Mobile Assessment and Messaging.

    SBC: MOBILE HEALTH INTERVENTIONS, LLC            Topic: NIDA

    DESCRIPTION (provided by applicant): This Phase I SBIR application entitled Substance Abuse Continuing Care through Mobile Assessment and Messaging is designed to create a low cost, continuous care decision support text messaging intervention to increase treatment adherence, decrease drop-out and prevent the recurrence of problem drug use during and following professionally facilitated addiction ...

    SBIR Phase I 2010 Department of Health and Human Services
  3. Ion Channel Drug Discovery Using Photoswitch Technology

    SBC: PHOTOSWITCH BIOSCIENCES, INC.            Topic: NIGMS

    DESCRIPTION (provided by applicant): Ion channels are membrane proteins that allow the selective movement of charged molecules through cellular membranes. Many disease states, such as cystic fibrosis, muscular dystrophies, hypertension, and cardiac arrhythmias are caused by ion channel pathologies. Ion channels have been identified by the drug discovery community as excellent targets for therapeut ...

    SBIR Phase I 2010 Department of Health and Human Services
  4. Vision restoration with photoswitch technology

    SBC: PHOTOSWITCH BIOSCIENCES, INC.            Topic: NEI

    DESCRIPTION (provided by applicant): Retinitis Pigmentosa (RP) is an inherited disease of the eye that robs its victims of vision. The loss of vision is caused by the degeneration of the rods and cones of the retina while other cells in the retina remain alive. RD is a relatively rare disease, affecting approximately 100,000 people in the US. Approximately 20% of children in schools for the blind ...

    SBIR Phase I 2010 Department of Health and Human Services
  5. Pharmaceutical Therapy for Seasonal Affective Disorder

    SBC: PHOTOSWITCH BIOSCIENCES, INC.            Topic: NIMH

    DESCRIPTION (provided by applicant): Seasonal Affective Disorder (SAD) is one of the most common mood disorders, affecting 1-3% of the population in temperate climates, predominantly women. Currently, there are no specific drug therapies for SAD. Patients are prescribed general anti-depressants or bright light therapy. SAD symptoms include low mood, loss of interest, difficulty concentrating, loss ...

    SBIR Phase I 2010 Department of Health and Human Services
  6. Substance Addiction Collaboration Channel (SACC)

    SBC: Health Education Research Systems, llc            Topic: NIDA

    DESCRIPTION (provided by applicant): The SACC-Substance Addiction Collaboration Channel(R) platform is a new Collaboration, WEB-2.0 springboard specifically designed to structure and share information across the Behavioral/Mental Health Workforce community with the special focus on Substance-Addiction Disorders. SACC is an individual and group-level application platform that is akin to Facebook ...

    SBIR Phase I 2010 Department of Health and Human Services
  7. Single Cell Micro-chamber Array analysis

    SBC: E&M Devices            Topic: NIGMS

    DESCRIPTION (provided by applicant): Abnormalities in the cytosol of subpopulations of cells are often a hallmark of pathology. Most analysis methods will only provide information on the cytosol of cell populations as a whole, not for individual cells or subpopulations of cells. To overcome this, we propose to develop Single Cell Micro-chamber Array (SiCMA) technology. This approach is based on pr ...

    SBIR Phase I 2010 Department of Health and Human Services
  8. Reactive Rendezvous and Docking Sequencer

    SBC: BLUE SUN ENTERPRISES, INC            Topic: S504

    Mars Sample Return poses some of the most challenging operational activities of any NASA deep space mission. Rendezvous of a vehicle with a sample canister in order to return the canister to Earth requires a variety of complex mathematical processing on a changing data set, coupled with the need to safely and effectively handle a large range of off-nominal conditions and spacecraft faults. Light s ...

    SBIR Phase I 2010 National Aeronautics and Space Administration
  9. Dynamic Phase Imaging Interference 4D Microscope System

    SBC: 4 D Technology Corporation            Topic: NCRR

    DESCRIPTION (provided by applicant): We propose to develop a dynamic quantitative phase-imaging interference 4D microscope system operating in reflection to enable creating phase image movies and quantifying motion of live cells and cellular processes in vitro without the need for adding contrast agents, ultimately having application to clinical measurements in vivo. The primary use of this micros ...

    SBIR Phase I 2010 Department of Health and Human Services
  10. GP1002 as a Highly Pathogenic Influenza A Therapeutic

    SBC: GEMMUS PHARMA, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant) Influenza pandemics are considered one of the world's most devastating public health threats. The challenge for public health departments worldwide is to have an effective therapy on hand to prevent deaths during a pandemic influenza outbreak. Vaccines are effective, but have a lead time. Anti-viral drugs are partially effective, but are in limited supply and fa ...

    SBIR Phase I 2010 Department of Health and Human Services

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