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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

Displaying 50271 - 50280 of 173942 results
  1. High-Throughput Low Cost Production of Chromatin-Immunoprecipitation-Grade Antib

    SBC: Nectagen, Inc.            Topic: NHGRI

    DESCRIPTION (provided by applicant): Identifying the regulatory regions of the genome is critical for understanding the regulatory networks underlying human development and disease. Chromatin immunoprecipitation (ChIP) coupled with microarray (ChIP-chip) or sequencing (ChIP- seq) is a widely used technique for understanding the genome-wide binding pattern of regulatory proteins. A key bottleneck ...

    SBIR Phase I 2010 Department of Health and Human Services
  2. DEVELOPMENT OF ALTERNATIVE AFFINITY CAPTURE REAGENTS FOR CANCE

    SBC: Nectagen, Inc.            Topic: NCI

    Many of the antibodies produced for cancer research are poorly characterized, exhibit suboptimal affinity or selectivity, and are time-consuming and expensive to produce. Alternative affinity capture reagents are therefore needed as reproducible, highly characterized, rapid, and cost-effective substitutes for monoclonal antibodies. As a platform for creating affinity capture reagents, Aptakon has ...

    SBIR Phase I 2010 Department of Health and Human Services
  3. Youth Mental Health Outcomes Tracking System: Self, Parent, and Clinician-Reported

    SBC: TELESAGE RESEARCH, INC.            Topic: NIMH

    DESCRIPTION (provided by applicant): With funding from NIMH, TeleSage has developed a state-of-the-art mental health outcomes tracking survey instrument for use with both public- and private-sector adults. This survey is currently in statewide use in Tennessee and Iowa. Unfortunately, no corresponding cutting-edge survey instrument exists for youth. TeleSage has used the Ohio Scales in two state-w ...

    SBIR Phase I 2010 Department of Health and Human Services
  4. New CAT Research Tool:IRT/CAT Software for Secure Web and IVR Survey Administration

    SBC: TELESAGE RESEARCH, INC.            Topic: NIMH

    DESCRIPTION (provided by applicant): Computer Adaptive Testing (CAT) provides a new mechanism for assessing patient-reported outcomes. Using CAT can: (a) increase measurement precision, leading to a decrease in the number of participants necessary to achieve statistically significant results, (b) decrease test burden on respondents, compared to administration of fixed length surveys, thereby incr ...

    SBIR Phase II 2010 Department of Health and Human Services
  5. Phase-contrast enhanced X-ray imaging system for small joints of hand

    SBC: QUANTUM MEDICAL METRICS, LLC            Topic: NIAMS

    DESCRIPTION (provided by applicant): Rheumatoid Arthritis (RA) is a debilitating disease which affects nearly 1% of the US population. It initially attacks the small joints of the hand and foot. Recent RA research shows that early aggressive therapy is most effective, making early diagnosis essential. Currently the early subtle tissue effects of RA are best imaged with MRI and ultrasound. While ha ...

    SBIR Phase I 2010 Department of Health and Human Services
  6. C-SiC Honeycomb for Advanced Flight Structures

    SBC: Ultracor            Topic: A201

    The proposed project is to manufacture a C-SiC honeycomb structure to use as a high temperature material in advanced aircraft, spacecraft and industrial applications. The proposers will fabricate a carbon fiber honeycomb structure. The structure will be charred and then converted to C-SiC by means of chemical vapor infiltration. The resultant material will then be tested mechanically at ambient ...

    SBIR Phase I 2010 National Aeronautics and Space Administration
  7. Nanoporous silicon membranes for protein purification

    SBC: SiMPore, Inc.            Topic: NIGMS

    DESCRIPTION (provided by applicant): In this Phase I application we will examine the feasibility of producing high yield porous nanocrystalline silicon (pnc-Si) membranes for protein purification products. Membranes made of this material are a breakthrough technology, 1000x thinner than conventional and other nanoporous membranes, with tunable pore sizes (5-100 nm) and precise distributions. At ju ...

    SBIR Phase I 2010 Department of Health and Human Services
  8. Nanotechnology-enhanced High-efficient Miniaturized Energy Harvesting Systems

    SBC: ELORET            Topic: SB092001

    Performance of conventional primary and secondary batteries improve at a meager rate every year. Sensors and sensor networks which are advancing through relentless miniaturization effects need uninterrupted power sources in many scenarios. We propose to use a piezoelectric based energy scavenging device to harvest energy from environmental vibrations. Although a handful of structures by a few grou ...

    SBIR Phase I 2010 Defense Advanced Research Projects AgencyDepartment of Defense
  9. Recovery of In-Space Cubesat Experiments (RICE)

    SBC: ELORET            Topic: X901

    ELORET Corporation, in collaboration with the Space Systems Design Laboratory of Georgia Institute of Technology, proposes developing and demonstrating a capability/technology to de-orbit small payloads (approximately 1 kg) from Low-Earth Orbit and returning them to Earth safely. To achieve this goal, the current proposal has five objectives and associated tasks: 1. Surveying the Bio-science commu ...

    SBIR Phase I 2010 National Aeronautics and Space Administration
  10. Ultra-High Energy Density Piezoelectric Nanocomposites for Lightweight Power Harvesting Micro-Systems

    SBC: HARP ENGINEERING LLC            Topic: SB092001

    The proposed phase I research effort will develop a highly efficient MEMS energy harvesters that utilize a novel nanocomposite technology recently developed by Sodano Engineering LLC. Unlike existing piezoelectric nanocomposites, the material proposed here has an electromechanical coupling coefficient higher than the monolithic piezoceramics typically used in MEMS processing. The high coupling i ...

    SBIR Phase I 2010 Defense Advanced Research Projects AgencyDepartment of Defense

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