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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Optimization of small molecule triazine antituberculars for in vivo efficacy

    SBC: COLLABORATIONS PHARMACEUTICALS INC            Topic: NIAID

    DESCRIPTION provided by applicant Tuberculosis TB is due to infection with the pathogen Mycobacterium tuberculosis Mtb This disease represents a global health pandemic as based on WHO statistics it claims the lives of approximately million people per year while infecting nearly million New drugs are urgently needed with novel mechanisms of action that treat this disease while also ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  2. Assessing the Bite Counter as a Tool for Food Intake Monitoring

    SBC: BITE TECHNOLOGIES, LLC            Topic: NIDDK

    DESCRIPTION (provided by applicant): This proposal is in response to PA-07-436 Bioengineering Approaches to Energy Balance and Obesity (STTR [R41/R42]) . In this project we will assess a wrist-worn bite counter for monitoring food intake. Specifically,we will evaluate the device across different foods, liquids, utensils and containers to measure its utility for monitoring eating. We will create ...

    STTR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  3. N/A

    SBC: TRIANGLE LABORATORIES, INC.            Topic: N/A

    N/A

    STTR Phase I 2000 Department of Health and Human ServicesNational Institutes of Health
  4. Development of an endocannabinoid microparticle formulation for the topical treatment of cutaneous manifestations of lupus erythematosus.

    SBC: Zylo Therapeutics Inc.            Topic: NIAMS

    Project Summary/Abstract Approximately 500,000 people in the U.S. suffer from cutaneous lupus lesions (CLE), with a significant impact on quality of life.4 Yet, there is no cure, the treatment options are limited, and no new drug has been FDA- approved for over 50 years.84 As such, CLE represents a high unmet need for directed therapeutics. Skin lesions are caused by a complex autoimmune response ...

    STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  5. LifeSkills Video Training in Patients with Implanted ICD

    SBC: WILLIAMS LIFESKILLS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): This proposal is to develop a video / DVD cassette that will provide guidance about mastering stressful situations for patients who have been informed that they need an implantable cardioverter-defibrillator (AICD). We will adapt the existing "LifeSkills" video (which was already shown to be effective in patients with heart diseases) to the specific needs of pa ...

    STTR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  6. Non-Opiate Topical Formulations for Treating Pain Associated with Molar Extractions

    SBC: ARCATO LABORATORIES, INC.            Topic: NIDCR

    Project Summary Abstract Most of the deaths from drug overdoses are driven by synthetic opioidsDentistry highly contributes to the opiate addiction epidemicFollowing dental surgeryof oral surgeons prescribe opiatesand most opiates are prescribed after wisdom teeth extractionthird molarto reduce pain caused by dry socketsApproximatelymillion surgical tooth extractions are performed onmillion patien ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  7. Optimizing Operating Room Efficiency

    SBC: ADVANCED PROCESS COMBINATORICS, INC.            Topic: NIBIB

    DESCRIPTION (provided by applicant): Optimal use of operating room (OR) personnel and resources is an important problem from multiple perspectives. Unanticipated waits and delays continue to add tremendous costs and negatively impact outcomes. There are over 55 million ambulatory and 45 million inpatient procedures performed in the U.S. annually, with increasing case complexities and patient comor ...

    STTR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  8. Development of a Genetic Therapy for CF in a CF Rabbit

    SBC: EVERGEN BIOTECHNOLOGIES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The development of transgenic mouse models for cystic fibrosis (CF) has been an important contribution to our understanding of CF and of CF transmembrane conductance regulator (CFTR) function. However, because of the dissimilarity between mouse and human anatomy and physiology, there are limitations in what can be discerned about CF pathology and in development ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  9. NOVEL NEUROTENSIN ANALOGS AS ANTISCHIZOPRENICS

    SBC: ARGOLYN BIOSCIENCE, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The brain peptide neurotensin (NT) and its active derivative NT [8-13] function as endogenous neuroleptics. Stable NT derivatives that cross the blood brain barrier therefore have significant potential for development as a new class of non-dopamineric antipsychotics expected not to display the adverse side effects associated with the dopaminergics. The best lit ...

    STTR Phase I 2002 Department of Health and Human ServicesNational Institutes of Health
  10. Engineered Biotherapeutic Agent for Treatment of Post-Traumatic Osteoarthritis

    SBC: Provizigen LLC            Topic: NIAMS

    PROJECT SUMMARY/ABSTRACT Post-traumatic osteoarthritis (PTOA) is a degenerative disease of cartilage brought on by traumatic injury to the articular joints. Acute joint injury is followed by severe joint pain and inflammation. This results in much more rapid degeneration of cartilage than in other forms of osteoarthritis, due to the joint instability caused by trauma as well as the increase in pro ...

    STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
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