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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. SYNERGY PC CARRY ELECTRONIC COMMUNICATION DEVICE

    SBC: SYNERGY            Topic: N/A

    DESCRIPTION: (Adapted from the applicant's abstract) Synergy will produce a prototype for the Synergy PC-Carry Electronic Communication Device, a PC- Computer-based speech prosthesis for ambulatory persons with communication and or cognitive deficits. Survey of customers and review of the available prostheses reveal a demand for this product. Research will be conducted at Synergy and at the cons ...

    SBIR Phase I 1997 Department of Health and Human Services
  2. Synthesis of Cyclic ADP Ribose

    SBC: Research Biochemicals,            Topic: N/A

    We will develop the total synthesis of cyclic adenosine diphosphate ribose (cADPR). We envision a csynthesis in which the morpholine- activated phosphoroamidate N,N'-dicyclohexylcarboxamidine salt of'phosphate is coupled to 2,3,5-tri-O-benzoyl-D-ribose. The protecting groups will be removed and thecyclized to produce the desired final product, cADPR. The synthetic material will be fully charactert ...

    SBIR Phase I 1995 Department of Health and Human Services
  3. SYNTHESIS OF PEPTIDE AND NONPEPTIDE OPIOID ANALOGS

    SBC: Solid Phase Sciences            Topic: N/A

    N/A

    SBIR Phase I 1997 Department of Health and Human Services
  4. Synthesis of Rigid Analogs of Antipsychotic Clozapine

    SBC: Pharm-Eco Laboratories            Topic: N/A

    This proposal is for the synthesis and testing of rigid analogs of the antipsychotic drug clozapineclozapine does not cause extrapyramidal and endocrine side effects that are typical of antipsychoticagranulocytosis in 1-2% of schizophrenics who take the drug. Because of this, there is a need for aantipsychotic drug that does not cause this potentially fatal side effect. Based on molecular modeliid ...

    SBIR Phase I 1995 Department of Health and Human Services
  5. Synthetic Insulin Mediators as Therapeutic Agents

    SBC: Insmed Pharamaceuticals, Inc.            Topic: N/A

    Insulin's action on specific transmembrane receptors releases low molecular weight substanceswhich exhibit remarkable insulin mimetic properties. This data indicates that insulin resistance couldlikely be a post-receptor defect since these low molecular weight substances mediate insulin's actionon the cell or in vivo. These mediators are inositol phosphoglycan linkers positioned between the cellme ...

    SBIR Phase I 1994 Department of Health and Human Services
  6. Synthetic Sod/Catalase Mimics for Autoimmune Disease

    SBC: Eukarion, Inc.            Topic: N/A

    ROS are believed to cause tissue damage in numerous pathological conditions including chronic autoidisease. We have developed a class of low molecular weight catalytic ROS scavengers with a lead molehighly effective in several experimental models for disease. This project will investigate the efficautoimmune disease, focusing on systemic lupus erythematosus (SLE), a chronic disorder with frequentw ...

    SBIR Phase I 1995 Department of Health and Human Services
  7. SYSTEM FOR CONVERTING SPEECH INTO SYNTHESIS PARAMETERS

    SBC: Audiofile, Inc.            Topic: N/A

    N/A

    SBIR Phase I 1991 Department of Health and Human Services
  8. TACTILE GRAPHIC PRINTER PROJECT (TGPP)

    SBC: Automated Functions, Inc.            Topic: N/A

    N/A

    SBIR Phase I 1996 Department of Health and Human Services
  9. TARDIVE DYSKINESIA ANALYSIS SYSTEM FOR NURSING HOMES

    SBC: Computerist, Inc.            Topic: N/A

    N/A

    SBIR Phase I 1996 Department of Health and Human Services
  10. Targeted IGF-I/PDGF for Estrogen Deficiency Osteoporosis

    SBC: Institute Of Molecular            Topic: N/A

    Postmenopausal (estrogen deficiency-induced) osteoporosis is a major public health problempredisposing to fracture and resulting in significant morbidity and mortality. Current therapies canstabilize bone mass but can not repair or restore lost bone. Thus, a critical need exists to improvetherapeutics for the treatment of osteoporosis. Growth factors are essential for bone repair, andexogenous gro ...

    SBIR Phase I 1994 Department of Health and Human Services
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