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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. STEM lesson creation coaching framework to improve the pedagogy of K-5 teachers implementing the NGSS

    SBC: StarrMatica Learning Systems, Inc.            Topic: 86

    A highly effective teacher in elementary school is essentialto a student's future success in STEM fields—yet many rural elementary teachers report feelingunprepared and uncomfortable teaching science. Research shows they often lack adequatecontent knowledge and have low confidence in their science instruction. The new demands setby the Next Generation Science Standards (NGSS) compound these ...

    SBIR Phase II 2020 Department of Agriculture
  2. A Hybrid Electrodialysis/Electrolysis Unit for Combined Nitrate Removal and Conversion from Agricultural Wastewater

    SBC: PANI CLEAN INC            Topic: 84

    Nitrate is currently the most prevalent groundwater pollutant in Northern America primarily fromagricultural activities and changing nitrogen input to the land surface. In the US over 7 millionAmericans drink water from community water systems (CWS) that contain nitrate (NO ) at3 concentrations exceeding the maximum contaminant level (MCL). The go-to technologies fornitrate treatment from CWSs pro ...

    SBIR Phase II 2020 Department of Agriculture
  3. Discovery of Novel Pharmaceutical Agents for Skeletal Muscle Atrophy

    SBC: EMMYON, INC.            Topic: NIAMS

    PROJECT SUMMARY / ABSTRACT Skeletal muscle atrophy diminishes the health and quality of life of tens of millions of people in the US alone. Frequent causes of muscle atrophy (which often co-exist in the same patient) include aging, malnutrition, muscle disuse, critical illness, certain medications, and a broad range of chronic illnesses including cancer, heart failure, COPD, diabetes, renal failur ...

    SBIR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health
  4. Improving The Reproducibility and Genetic Stability of IPSC and Differentiated Cells Through Oncogene-Free Reprogramming and Fully Human Growth Factors

    SBC: Cellular Engineering Technologies, Inc.            Topic: 400

    Cellular Engineering Technologies (CET) has submitted this proposal in response to RFA-GM- 19-001. CET has proposed a direct Phase II SBIR application to create more reproducible human induced pluripotent stem cells (iPSCs) and create methods for growing, maintaining, and authenticating iPSCs. A major challenge in iPSC manufacturing and subsequent differentiation is the emergence of genetic instab ...

    SBIR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health
  5. GMP peptide manufacturing, pharmacology/toxicology, and scaled radionuclide production and validation for Pb-212 receptor targeted alpha-particle therapy clinical trials for metastatic melanoma.

    SBC: VIEWPOINT MOLECULAR TARGETING, INC.            Topic: NCI

    Melanoma incidence in the United States is growing rapidly. Surgery combined with radiation can be curative at early stages but, metastatic melanoma is usually fatal. Since 2011, targeted MAPKi and immunotherapies have improved outcomes, but low response rates, acquired resistance, and adverse events limit quality of life for these patients (5-yr. survival andlt;25%). Under predicate Randamp;D, Vi ...

    SBIR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health
  6. Development of a Micro-Mechanical Insertion Tool with Intraoperative Real-Time Electrophysiological Sensing Control for Cochlear Implantation

    SBC: iotaMotion, Inc.            Topic: NIDCD

    Project Summary/Abstract. One of the more recent goals of cochlear implant (CI) surgery is the preservation of residual hearing to improve overall patient outcomes. Unfortunately, up to 50% of patients experience delayed residual hearing loss following cochlear implant surgery, resulting in a diminished quality of life. To address this issue, iotaMotion is developing an insertion system to assist ...

    SBIR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health
  7. Preclinical pharmacology, toxicology, biodistribution and dosimetry, and radionuclide production CMC validation for Pb-212 receptor targeted alpha-particle therapy for neuroendocrine tumors.

    SBC: VIEWPOINT MOLECULAR TARGETING, INC.            Topic: NCI

    Neuroendocrine tumors (NET) are enigmatic malignancies, with an increasing incidence and poor outcomes (5-yr survival andlt;30%). Recently, peptide-receptor radionuclide therapy (PRRT) using [177Lu]DOTATATE beta(b)-particle treatment (LutatheraÔ) improved survival vs standard of care and was FDA approved. However, objective tumor responses were low (18%) in the Phase 3 trial. Nonetheless, Lutathe ...

    SBIR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health
  8. Generalizing and Standardizing fMRI Tools for Differentiating Mental Illnesses and Predicting Medication-Class Response in Patients

    SBC: ADVANCED BIOMEDICAL INFORMATICS GROUP, L.L.C.            Topic: 102

    Project Summary/AbstractMood disorders, like many psychiatric conditions, have their onset in emerging adulthood and often last a lifetime. Mental illnesses have an excessively large loading of Disability Adjusted Life Years, making early intervention crucial for both individuals and society. Differentiating bipolar disorder (BD) from major depressive disorder (MDD) based on the Diagnostic and Sta ...

    STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  9. Circulating Diagnostic Markers of Infectious Disease

    SBC: PATHOVACS INCORPORATED            Topic: CBD18A001

    Assays for accurate diagnosis of early stages of infection with biothreat agents, on the day of infection or within a few days of infection, will find wide use in both civilian and military applications These diagnostic assays, which are anticipated to be highly specific and sensitive, will add to the repertoire of tools of hospitals and clinics that serve our armed forces personnel deployed on th ...

    STTR Phase II 2020 Department of DefenseOffice for Chemical and Biological Defense
  10. Ultra-flexible high efficiency photovoltaics

    SBC: POWERFILM INC            Topic: A18067

    Currently packable panels are made from low efficiency light-weight Amorphous Silicon or carbon fiber backed crystalline silicon. The weakness of the amorphous silicon technology resides in the power conversion efficiency (watts per unit area), while the carbon fiber backed crystalline silicon cells lack field durability, flexibility and are bulky. The solution to this problem is to take the benef ...

    SBIR Phase II 2020 Department of DefenseArmy
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