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DESCRIPTION provided by applicant Catheter associated urinary tract infections CAUTIs are often encountered with subsequent antibiotic administration contributing to buildup of bacterial resistance Leaving behind customary methods including release of silver and antimicrobials PEG LLC will develop a new approach whereby catheters are overcoated with a thin film that kills bacteria on contac ...

DESCRIPTION provided by applicant Glioblastoma accounts for of all brain tumors and is the most common and most malignant form of glioma Primary glioblastomas show rapid disease progression without precursor lesions whereas secondary glioblastomas generally originate as low grade astrocytomas that form grade IV gliomas over a period of years Without prior knowledge of a patientanda ...

DESCRIPTION provided by applicant The legalization of marijuana in Colorado and Washington in is the most dramatic change in substance abuse policy in the United States since the end of Prohibition These states are implementing regulatory and enforcement systems for the retail sales of recreational marijuana to adults years or older akin to state controls on the sale of alcohol In ...

DESCRIPTION provided by applicant This SBIR project seeks to develop novel technologies for the manipulation and labeling of the interior of living eukaryotic cells for research diagnostic and eventually therapeutic purposes Cell penetrating peptides offer the tantalizing prospect of delivering a broad palette of user defined protein cargoes through the plasma membranes of eukaryotic cells C ...

DESCRIPTION provided by applicant Epigenetic modifications of DNA and histones are stable encryption systems essential for life For example the importance of DNA methylation is underscored by the consequences of its mis regulation which include defects in tissue homeostasis chronic disease and accelerated aging thus epigenetics broadly impacts human health The information stored in the di ...

DESCRIPTION provided by applicant To combat Healthcare Associated Infection HAI which is now the rd leading cause of death in the U S TDA Research Inc proposes to develop new antimicrobial copper alloy coatings for high touch stainless steel surfaces that may be responsible for of all HAI Low cost durable coatings will be scientifically designed for the catalytic production of hyd ...

DESCRIPTION provided by applicant Efficacy of human stem primary cells for biomedical applications hinges upon successful in vitro culture and manipulation Cell attachment and growth represent critical steps that dictate the overall culture success To promote cell attachment and growth animal or human origin extracellular matrix ECM proteins are widely used ECM not only provides structura ...

DESCRIPTION provided by applicant Objectives and optics for are rapidly evolving to allow wider and wider FOVs for two photon laser scanning microscopes PLSM This development introduces a new challenge point by point raster scanning over the entirety of the FOV requires the experimenter to sacrifice either single cell sensitivity because of faster scanning rates required to cover the lar ...

DESCRIPTION provided by applicant Barron Associates Inc BAI has teamed with the University of Virginiaandapos s UVAandapos s Motion Analysis and Motor Performance MAMP laboratory to propose development of an advanced control and computer learning strategy that will intelligently drive a powered walker for people with neuromuscular walking disabilities The aim of the control strategy is ...

DESCRIPTION provided by applicant One in Black men will be diagnosed with HIV in his lifetime as compared to in White men Approximately of all new HIV cases among African American men are due to heterosexual transmission Despite this Black men who have sex with women MSW have received very little empirical attention Traditional gender roles and power inequalities tend to give ...