Award Data

PROJECT SUMMARY Childhood (diffuse) interstitial lung diseases affects infants, children, and teens and manifests as dyspnea, hypoxemia, and respiratory compromise resulting in high morbidity and mortality or life-long sequelae for survivors. Despite improvements in the understanding of and interventions for pediatric diffuse lung disease in the past 15 years, the current standard-of-care for conf ...

Project Abstract In this Phase I SBIR project, ASTER Labs will develop and evaluate an innovative system to automatically and accurately detect Activities of Daily Living (ADL) performed by persons with Alzheimer’s disease and related dementias. It will address a current need to equip caregivers and health care providers, including physicians and cognitive rehabilitation therapists, with reliabl ...

Abstract Koronis Biomedical Technologies (KBT) and its collaborators propose to develop and fully validate a low-cost, developmentally appropriate, smartphone-based cognitive intervention for young children. The proposed intervention seeks to address the needs of families with young children identified with deficits in Executive Function (EF), a critical set of cognitive processes associated with ...

Abstract A 2019 study from the CDC estimated 812,000 children (age 17 or younger) were treated in U.S. emergency departments for concussion or Traumatic Brain Injury (TBI), alone or in combination with other injuries in 2014. Another recent study, which specifically focused on children’s sports and recreation-related TBIs found the number of related emergency department visits averaged more than ...

Project Summary/Abstract Proposed is a sleep monitoring system specifically designed for care providers of persons with Alzheimer’s disease and Alzheimer’s Disease Related Dementias (AD/ADRD) to monitor sleep disturbances and trends. Significance: Studies indicate that approximately 1 in 3 patients with AD/ADRD suffer from sleep and other nighttime disturbances such as insomnia and disruption ...

PROJECT SUMMARY/ABSTRACT More than 228,000 people in the United States will receive a lung cancer diagnosis this year. Only 14%-49% of early-stage patients survive at least 5 years after their diagnosis, and the survival rates fall below 5% for patients with advanced-stage IIIB or IV. Tumor recurrence after resection is a critical factor influencing these poor prognoses. If any cancerous tissue is ...

Project Summary/Abstract 30.3 million Americans are diabetic w/ 1.5 million new cases per year. Hypoglycemia negatively affects diabetics. The average type 1 diabetic experiences 2 symptomatic hypoglycemia episodes/week. Severe hypoglycemia (need for 3rd party assistance) results in 1.0 – 1.7 episodes per patient per year. Annually, 73% of insulin dependent type 2 diabetics experience hypoglycem ...

Project Summary/AbstractOlder adults with Alzheimer's disease (AD) and AD-related dementias (ADRD) need a trusted financial advocate to help orchestrate and oversee their care as they age. Spousal and adult child caregivers need comprehensive education around financial caregiving and tools on how to access resources to pay for long- term services and supports (LTSS). This SBIR project will create ...

Project Summary/Abstract Minnesota HealthSolutions Corporation and Children’s Hospital Los Angeles propose to develop a novel pediatric/neonatal endotracheal tube securement system with the aim of reducing unplanned extubation and associated complication rates. Mechanical ventilation through an endotracheal tube is routine in pediatric and neonatal intensive care units and has contributed to imp ...

Project Abstract In this Fast-Track SBIR project, ASTER Labs will address an urgent, immediate, need for accessible and accurate contact tracing to aid management of infectious disease outbreaks in long-term care facilities of patients with Alzheimer’s disease and related dementias. An estimated 5.8 million Americans in 2020 live with Alzheimer’s dementia and nearly half of nursing home and ot ...