Award Data

This contract aims to identify novel parasite derived protein candidates as biologics to treat Crohn s and other diseases with high healthcare costs and no truly long term effective treatment optionsWe will screen stage specific proteins from Onchocerca volvulus that conceivably enable this parasitic helminth to chronically infect the human host by continuously modulating the innate and adaptive i ...

Blast induced Traumatic Brain Injury (TBI) is a major threat to the health of military personnel serving in modern theaters. As such, the biomechanical injury pathways of TBI are, and have been, the focus of many animal studies. However, differences in the experimental setups across laboratories make it difficult to draw definitive conclusions from the resulting data. A tool that can accurately es ...

Soldiers with spinal cord injury (SCI) face a lifetime of bladder dysfunction.Although the type and character of this dysfunction depends on the severity and level of spinal injury, many of these soldiers and veterans suffer from renal insufficiency, frequent and severe antibiotic-resistant bladder infections, and the emotional and social stress of unexpected bladder leakage.We propose that signif ...

Vascular access is among the first and most critical steps in the stabilization and treatment of critically injured soldiers and civilians. In the field, where patients are volume-depleted from blood loss or dehydration, vasoconstricted, or hypothermic, traditional peripheral venous access and CVC access becomes exceedingly difficult. We propose a self-contained device that significantly simplifie ...

The nature of military operations leads to high noise levels, exposing personnel to the possibility of noise induced hearing loss (NIHL). Individual hearing monitoring is conducted yearly which can only provide a record of the progression of irreversible hearing loss with limited options for intervention and mitigation. Furthermore, there is limited data that links actual, real-world noise exposur ...

Hearing loss is the third most common chronic physical condition in the U.S.more prevalent than diabetes or cancer. Globally, in 2015, about one half billion people had disabling hearing loss, or roughly 6 to 8% of the world population. Occupational hearing loss is one of the most common work-related illnesses and the most common service-related disability among veterans. As a result, more individ ...

Mentis Sciences Inc. (Mentis) proposes to develop a refurbishment program that is capable of disassembling, inspecting, and re-building complex systems and components, with the initial system of focus being the Minuteman Missile Antenna/Antenna Pedestal Assembly.To become a refurbishment supplier, Mentis will develop and adapt inhouse processes for performing refurbishment services by leveraging c ...

Infrasound and seismic measurements are used by DTRA and the DoD for nuclear test monitoring, terrorist blast forensics, battle damage assessment, and environmental monitoring. However, these long wavelength physical signals are typically recorded through single-point sensors or sparse low density arrays. As a result, the critical signals of interest are often corrupted or masked by noise or inter ...

Mentis Sciences Inc. proposes to develop Technical Data Packages and generate Source Approval Requests for critically needed components for the Air Launched Cruise Missile engine platform, the F107, which is no longer supported by the OEM. The supply of some spare parts may be exhausted as early as Oct 2018, on a system that is scheduled to remain in service through at least 2030.Mentis will work ...

Ablative coatings for hypersonics are tested at facilities such as the AEDC Range G and the Holloman High Speed Test Track. A test article is accelerated to velocity up to 18,000 ft/s in a relevant atmosphere and travels up to 10,000 ft. It is important to measure the coating erosion at multiple discrete points along the trajectory to characterize non-linear ablation response.Existing measurement ...