Award Data

The broader/commercial impact of this Small Business Innovation Research (SBIR) Phase II project is an increase in the representation of women in Science, Technology, Engineering, and Math (STEM) employment areas, enabling the US to meet the increasing demand for STEM workers and maintain competitiveness in the global innovation community. The factors contributing to the underrepresentation of gir ...

This Small Business Technology Transfer (STTR) Phase II project contributes to broader societal and commercial impacts by enabling crime labs to better utilize overstretched resources by ensuring only relevant crime scene samples undergo DNA analysis. Currently, the large number of irrelevant samples submitted for testing contributes to a massive backlog that clogs up crime lab workflows and delay ...

The broader impact of this Small Business Research (SBIR) Phase II project is to reduce methane production in the ruminant livestock industry via the commercial production of Asparagopsis taxiformis for inclusion in cattle feed. There are currently 1.5 billion head of cattle on earth, which contribute significantly to greenhouse emissions via methane release during growth. It has been demonstrated ...

An area significantly lacking in first responder situational awareness is accurate responder location within various types of building structures above ground and underground such as tunnels and basements where GPS coverage is unavailable. GPS alternatives that rely on pre-deployed infrastructure such as indoor WiFi or mobile wireless networks or require the deployment of uncrewed aerial vehicles ...

Abstract Radiation induced keratopathy results in significant ocular surface disease, stem cell deficiency, vision loss, discomfort, and subsequent poor quality of life, affecting up to 23% of patients receiving radiation therapy for head and neck malignancies [1]. Studies have pointed out functional roles of corneal neurons and secretory cells of the lacrimal gland in the etiology of radiation in ...

PROJECT SUMMARY/ABSTRACT The cysteine protease caspase-6 (Casp6) has been associated with neurodegenerative diseases for over fifteen years. In Alzheimer’s disease (AD), Casp6 is colocalized with amyloid plaques and tau tangles in human brain, and both human and animal model data indicate that activated Casp6 contributes to neuronal inflammation, neurodegeneration, and cleavage of proteins to to ...

This project will achieve a computerized system that supplies digital content, both lexical and graphical, suitable for children, students and working adults of the Visually Impaired (VId) community, to increase their autonomy and potentiate their Quality of Life and societal contribution. While there is notable academic research, such as a high-density pin display tablet, there is no commercial, ...

PROJECT SUMMARYThe ocular surface (OcS) comprises the stratified squamous epithelia of the cornea/conjunctiva, its adnexa, and the overlying tear film. OcS disease disrupts the normal developmental progression, maturation, and turnover of OcS epithelia, causing “epitheliopathy” characterized by cell damage, barrier disruption and programmed cell death. OcS disease initiated by tear dysfunction ...

1 Approximately 6.5 million Americans aged 65 and older live with dementia, supported by more than 11 million2 unpaid family caregivers. These numbers are projected to rise exponentially in the coming decades fueling the3 need to develop scalable ways to support dementia caregivers. The need to empower dementia caregivers to4 continue providing care while maintaining their own health and well-bein ...

Each day, more than 100,000 patients undergo general anesthesia in the United States. The current practice of general anesthesia is prone to over-sedating patients, either due to the lack of brain monitoring or using brain monitors with inaccurate indices. Over-sedation (at 28% incidence) contributes to perioperative neurocognitive disorders (PNDs) in elderly population (≥65yrs). The cost of PND ...