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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Image Analysis Tools for mpMRI Prostate Cancer Diagnosis Using PI-RADS
SBC: ZMK Medical Technologies, Inc. Topic: 102ABSTRACTProstate cancerPCais one of the most commonly occurring forms of canceraccounting forof all cancer in menMulti parametric magnetic resonance imagingmpMRIhas led to improved capabilities for detectinglocalizingand staging PCaCombined with image guided prostate biopsympMRI has helped to improve diagnosis of clinically significant PCawhich helps to reduce mortality as well as unnecessary biop ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Automated preparation of single-cells and nuclei from solid tissues
SBC: S2 GENOMICS, INC Topic: 172Project Summary AbstractThis project designsdevelopsand automates a novel system to process solid tissue into single cellssingle nucleiand high molecular weight DNA using disposable cartridges without user interventionThe system will support downstream single cell RNA or DNA sequencingsingle nuclei RNA or DNA sequencingand long read sequencers and optical mappingThe long term goal of the project i ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Advancing Formulation of STING agonist for Universal Flu Vaccine
SBC: IMMvention Therapeutix, Inc. Topic: NIAIDSummary Influenza virusa member of the orthomyxovirus familyhas three different types that infect humansABand CTypes A and B produce annual epidemicsand type A influenzawhich resides asymptomatically in birdscan cause pandemic infections in humansIn addition to common flu like symptomse gfeverchillsmalaisemuscle painin susceptible populations influenza can induce potentially fatal secondary compli ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Discovery of novel CDK4/6-PI3K-BRD4 inhibitor SRX3177 for augmented anti-cancer activity
SBC: SignalRx Pharmaceuticals Inc. Topic: 102Three CDKinhibitors were recently approved to treat breast cancerBrCAin combination regimentsDespite significant clinical activitytreatment of BrCA patients with these combinations does not result in a durable responseHencethere is an unmet medical need to develop targeted therapeutic agents which will augment the activity of CDKinhibitors in BrCA and other CDKcyclin D Myc dependent malignanciesA ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Amelioration of rhinovirus induced asthma exacerbations by serpin B1
SBC: SERPLUS TECHNOLOGY LLC Topic: NIAIDPROJECT SUMMARY Asthma exacerbations are a major cause of ER visits and hospitalizations with annual direct costs of approximately $billionyear in the USAViral infectionsin particular rhinoviralRVinfectionsare a major precipitant of asthma exacerbations in allergic asthmaticsAs there are overRV serotypes andfor nowno RV vaccinenovel strategies to inhibit RV induced airway inflammation are needed t ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Protein ProFiler Microfluidic Electrophoresis System for Proteomics
SBC: INNOVAREGI LLC Topic: 400AbstractThe current estimate of the number of human genes is aboutin contrast to the number of presumed proteinswhich likely exceeds one millionThis increased complexity is the result of post transcriptional and post translational modificationsPTMsoccurring at multiple sites and in a quantitative variable mannerThe overwhelming result is a combinatorially expanding complexity of proteoforms that i ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Point of care detection of extracellular vesicles in urine for diagnosis of preeclampsia
SBC: Sersense Inc Topic: NICHDPreeclampsiaPEis a pregnancy specific disorder characterized by hypertension and commonly by the appearance of urinary proteinThis disorder occurs inof pregnancies worldwide and is the second leading cause of maternal fetal morbidity and mortality worldwideIn low resource settingsPE accounts for up toof maternal deathsThe etiology of this disease is poorly understoodThis confounds therapeutic inte ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Astroglial EAAT2 Changes in Live TBI Brain Determined by PET Imaging
SBC: RIO PHARMACEUTICALS, INC. Topic: NINDSPROJECT SUMMARYTraumatic Brain InjuryTBIis one of the most significant Public Health trauma diseases of our timeDiagnoses of various TBI forms rely on patient self reportingestablished clinical rating scalesand multimodality imaging to an extentTBI elicits complexheterogeneous pathological eventsincluding mechanical injuryhemorrhageand progressive secondary processes such as central and peripheral ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
A scalable system for high throughput, chronic electrophysiology in translational rodent research
SBC: SPIKEGADGETS, INC. Topic: 101Psychiatric disorders give rise to aberrant patterns of activity within the complex neural circuits of our brainsYetthe exact nature of these abnormal patterns is often unknown to developers of new treatmentsThe goal of this project is to enable circuit oriented research of neuropsychiatric diseases using rodent disease modelsThe long term objective is to catalyze the discovery of new therapeutic ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Clinical Translation of a Caveolae Targeting Antibody for Enhancing Cancer Drug Delivery
SBC: Cavatar LLC Topic: NCIPROJECT SUMMARY This proposal aims to develop a novel caveolae targeting antibody for rapid clinical translationIts long term objective is to develop the caveolae pumping systeman active transendothelial transport pathwayto provide an effective solution to the delivery and toxicity problem of systemically administered chemotoxinsWork will be based on the current proprietary mouse monoclonal antibo ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health