Award Data

There has been considerable interest in the development of alternative therapies for pain management that are neither opioid nor non-steroidal anti-inflammatory drugs (NSAIDs). Kalyra Pharmaceuticals has demonstrated that acetaminophen, also known as APAP

A key bottleneck to be addressed in regenerative medicine is hypothermic preservation of cells and tissues, which has been shown to extend survival of cell and tissue-based therapies by decreasing ischemic effect. However, preservation technology is aged, toxic and less effective than desired with typical cell survival post-thaw below 50% and unreliable potency. Current technology greatly hinders ...

Strategic Operations is noted for its rapid prototyping, manufacturing, distribution, and training capabilities; while Vcom3D is a leader in developing and fielding highly effective game-based learning products. The transition from R&D to manufacturing the Blended VR/Manikin Humeral Head IO Trainer for the Army and other military service use and commercialization to the civilian market will be se ...

Trauma is the most common cause of death in ages 1-48. Uncontrolled hemorrhage in the torso is the leading cause of preventable death in military combatants and civilian trauma patients with otherwise survivable injuries. The prospects for survival from hemorrhage-induced traumatic cardiac arrest (HiTCA) are dismal with only about a 1% survival rate. Advances in endovascular technologies have led ...

To effectively counter Weapons of Mass Destruction (WMD) we must be able to accurately and sensitively detect the sites of WMD development. While the reagents and byproducts of nuclear activity may be rapidly depleted from environmental sites, those transient perturbations leave a lasting mark on the resident microbial communities by promoting and restricting the growth of different microorganisms ...

Aret Associates and Oak Ridge National Laboratory (ORNL) propose an interdisciplinary effort to meet the challenges of developing a soil microbiome-based nuclear activity biomonitoring application. Our approach combines Arets expertise in decision theory and bioinformatics with ORNLs subject matter expertise in microbial ecology and contaminant signatures. We will adapt and extend our high featu ...

With the advent of high-density low-power sub-20nm technology processes and circuits with tens-of-billions of transistors, radiation-induced single-event effects present a new set of design challenges for terrestrial applications. Developing reliable single-event effect resilient microelectronics in these modern technology nodes is a resource and time-intensive endeavor that further requires valid ...

Over 820 million Indians, about 65% of its population, cook on polluting open fires, causing ~1 million premature deaths annually. Fifty million households have no electricity. The Power Stove is a household energy solution combining clean cooking and reliable, ondemand power. Clean combustion and thermoelectric power technology, make it a high performance, user desirable solution based on low cos ...

To address the DoDs Chemical and Biological Defense (CBD) program need for the development of real-time analytical technology for multicomponent vapor identification and quantification, Physical Optics Corporation (POC) proposes to develop a new Photoacoustic Gasses Optical Detector and Analyzer (PAGODA). It is based on a new system design that utilizes a novel, POC-developed photoacoustic transdu ...

To address the CBDs need for adjustable optical correction technology for respiratory protective systems, Physical Optics Corporation (POC)proposes to continue the development of a new low-cost Adaptive Lens for Ocular Correction (ALOC). The ALOC is formed by thin-filmmicroarrays of wavefront correctors (MWCs), which are conformably laminated onto the facemask visor and controlled by a miniature d ...