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SBC: Kalyra Pharmaceuticals, Inc. Topic: NonDOD
There has been considerable interest in the development of alternative therapies for pain management that are neither opioid nor non-steroidal anti-inflammatory drugs (NSAIDs). Kalyra Pharmaceuticals has demonstrated that acetaminophen, also known as APAPSBIR Phase II 2017 Department of DefenseDefense Health Agency
SBC: X-Therma Inc. Topic: DHP16012
A key bottleneck to be addressed in regenerative medicine is hypothermic preservation of cells and tissues, which has been shown to extend survival of cell and tissue-based therapies by decreasing ischemic effect. However, preservation technology is aged, toxic and less effective than desired with typical cell survival post-thaw below 50% and unreliable potency. Current technology greatly hinders ...SBIR Phase II 2017 Department of DefenseDefense Health Agency
SBC: Strategic Operations, Inc. Topic: DHP13001
Strategic Operations is noted for its rapid prototyping, manufacturing, distribution, and training capabilities; while Vcom3D is a leader in developing and fielding highly effective game-based learning products. The transition from R&D to manufacturing the Blended VR/Manikin Humeral Head IO Trainer for the Army and other military service use and commercialization to the civilian market will be se ...SBIR Phase II 2017 Department of DefenseDefense Health Agency
SBC: RESUSITECH, INC. Topic: DHP16009
Trauma is the most common cause of death in ages 1-48. Uncontrolled hemorrhage in the torso is the leading cause of preventable death in military combatants and civilian trauma patients with otherwise survivable injuries. The prospects for survival from hemorrhage-induced traumatic cardiac arrest (HiTCA) are dismal with only about a 1% survival rate. Advances in endovascular technologies have led ...SBIR Phase II 2017 Department of DefenseDefense Health Agency
SBC: Reference Genomics, Inc. Topic: DTRA162002
To effectively counter Weapons of Mass Destruction (WMD) we must be able to accurately and sensitively detect the sites of WMD development. While the reagents and byproducts of nuclear activity may be rapidly depleted from environmental sites, those transient perturbations leave a lasting mark on the resident microbial communities by promoting and restricting the growth of different microorganisms ...SBIR Phase I 2017 Department of DefenseDefense Threat Reduction Agency
SBC: Arete Associates Topic: DTRA162002
Aret Associates and Oak Ridge National Laboratory (ORNL) propose an interdisciplinary effort to meet the challenges of developing a soil microbiome-based nuclear activity biomonitoring application. Our approach combines Arets expertise in decision theory and bioinformatics with ORNLs subject matter expertise in microbial ecology and contaminant signatures. We will adapt and extend our high featu ...SBIR Phase I 2017 Department of DefenseDefense Threat Reduction Agency
SBC: LUCID CIRCUIT, INC. Topic: DTRA162006
With the advent of high-density low-power sub-20nm technology processes and circuits with tens-of-billions of transistors, radiation-induced single-event effects present a new set of design challenges for terrestrial applications. Developing reliable single-event effect resilient microelectronics in these modern technology nodes is a resource and time-intensive endeavor that further requires valid ...SBIR Phase I 2017 Department of DefenseDefense Threat Reduction Agency
SBC: HI-Z TECHNOLOGY, INC. Topic: 15NCER02
Over 820 million Indians, about 65% of its population, cook on polluting open fires, causing ~1 million premature deaths annually. Fifty million households have no electricity. The Power Stove is a household energy solution combining clean cooking and reliable, ondemand power. Clean combustion and thermoelectric power technology, make it a high performance, user desirable solution based on low cos ...SBIR Phase II 2017 Environmental Protection Agency
SBC: Physical Optics Corporation Topic: CBD171004
To address the DoDs Chemical and Biological Defense (CBD) program need for the development of real-time analytical technology for multicomponent vapor identification and quantification, Physical Optics Corporation (POC) proposes to develop a new Photoacoustic Gasses Optical Detector and Analyzer (PAGODA). It is based on a new system design that utilizes a novel, POC-developed photoacoustic transdu ...SBIR Phase I 2017 Department of DefenseOffice for Chemical and Biological Defense
SBC: Physical Optics Corporation Topic: CBD152001
To address the CBDs need for adjustable optical correction technology for respiratory protective systems, Physical Optics Corporation (POC)proposes to continue the development of a new low-cost Adaptive Lens for Ocular Correction (ALOC). The ALOC is formed by thin-filmmicroarrays of wavefront correctors (MWCs), which are conformably laminated onto the facemask visor and controlled by a miniature d ...SBIR Phase II 2017 Department of DefenseOffice for Chemical and Biological Defense