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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Fluorescent Qdot-Antibody or Aptamer Test Strips for Ultrasensitive Algal Toxin Detection

    SBC: NANOHMICS INC            Topic: 9203

    Nanohmics, Inc. proposes to develop the most sensitive antibody and/or DNA aptamer‐quantum dot (Qdot)‐based lateral flow (LF) test strips possible for detection of harmful algal bloom (HAB) toxins in fresh or saltwater and seafood rinsates. Although commercial colloidal gold‐LF test strips for some HABs and anti‐HAB toxin aptamer DNA sequences already exist, Nanohmics’ innovation of inco ...

    SBIR Phase I 2020 Department of CommerceNational Oceanic and Atmospheric Administration
  2. FOLLOWING A POST-IRRADIATION THERMAL ANNEAL CYCLE

    SBC: Materials Engineering &            Topic: N/A

    THIS RESEARCH WILL DETERMINE THE CHARACTERISTICS OF FATIGUE INITIATION LIFE, FATIGUE CRACK GROWTH RATES, AND SLOW-STABLECRACK EXTENSIONS FOLLOWING A POST-IRRADIATION ANNEAL. FATIGUE INTITIATION LIFE WILL BE DETERMINED WITH SMOOTH SPECIMENS OF 308 STAINLESS STEEL WHICH HAVE BEEN ANNEALED AND THEN CYCLED IN PRESSURIZED, HIGH-TEMPERATURE WATER. SUBMERGED ARC WELD STEEL (LINDE 80 FLUX) WILL BE PARTIAL ...

    SBIR Phase I 1983 Nuclear Regulatory Commission
  3. Hand-Held Fluorometer Using Selex DNA Aptamer Strip Assays to Detect Cryptosporidium and Encephlitozoon

    SBC: Systems & Processes Engineering Corporation            Topic: N/A

    Systems & Processes Engineering Corporation (SPEC) proposes to develop receptors composed of DNA oligomers ("aptamers") from a combinatorial library for binding and detecting Cryptosporidium parvum oocysts and three species of Encephalitozoon spores. Aptamers will be generated by the Systematic Evolution of Ligands by EXponential enrichment (SELEX) combinatorial chemistry technique. SELEX aptamers ...

    SBIR Phase I 2001 Environmental Protection Agency
  4. Handheld FRET-Aptamer Sensor for Chem-Bio Threats

    SBC: Operational Techologies Corporation            Topic: J

    "Operational Technology Corporation (OpTech) proposes to couple the ultrasensitivity of fluorescence-based detection with the high selectivity of synthetic DNA aptamers as replacements for antibodies to detect chemical and biological (CB) terrorism threats in 10 minutes or less from a variety of swabbed surfaces and liquid matrices. OpTech has previously provided strong proof-of-concept for a rap ...

    SBIR Phase I 2011 Environmental Protection Agency
  5. Handheld FRET Aptamer Sensor to Satisfy the Beaches Act

    SBC: Operational Techologies Corporation            Topic: 06NCERC2

    Operational Technologies Corporation (OpTech) proposes to couple the ultrasensitivity of fluorescence-based detection with the high affinity and selectivity of DNA aptamers as improved replacements for antibodies to detect fecal indicator organisms in fresh and marine recreational waters. Fluorescence Resonance Energy Transfer (FRET) aptamer assays for fecal indicator organisms will be demon ...

    SBIR Phase I 2007 Environmental Protection Agency
  6. Handheld FRET Aptamer Sensor to Satisy the Beaches Act

    SBC: Operational Techologies Corporation            Topic: N/A

    Operational Technologies Corporation (OpTech) proposes to couple the ultrasensitivity of fluorescence-based detection with the high affinity and selectivity of DNA aptamers as improved replacements for antibodies to detect fecal indicator organisms in fresh and marine recreational waters. Fluorescence Resonance Energy Transfer (FRET) aptamer assays for fecal indicator organisms will be demonstrat ...

    SBIR Phase I 2007 Environmental Protection Agency
  7. High efficiency vertical photoconductive semiconductor switches (PCSS)

    SBC: NANOHMICS INC            Topic: DMEA231005

    Vertical Photoconductive Semiconductor Switches can be designed to support numerous filaments that simultaneously conduct current. A two dimensional array of current channels can be lithographically patterned on the surface of a substrate to achieve significant power scaling. One of the challenged is coupling the optical trigger signal efficiently into the filament apertures. Nanohmics will desig ...

    SBIR Phase I 2023 Department of DefenseDefense Microelectronics Activity
  8. Highly-Integrated SiC BiCMOS/Power Device Technology: Design, Modeling, and Reliability Metrics

    SBC: COOLCAD ELECTRONICS, LLC            Topic: DMEA211001

    We propose to lay the groundwork for the implementation of a completely integrated SiC BiCMOS/LDMOS technology for integrated control/power circuit applications reliable for operation up to 300 C. Our workplan to accomplish this goal comprises improving device speed and reliability by device engineering, establishing baseline reliability and qualification tests to support and certify development, ...

    SBIR Phase I 2021 Department of DefenseDefense Microelectronics Activity
  9. HIGH SENSITIVITY URANIUM BIOASSAY

    SBC: Eastern Analytical Inc.            Topic: N/A

    DETERMINATION OF URANIUM IN THE URINE OF WORKERS IS REQUIRED BY THE NRC AT NUCLEAR FACILITIES. EXTREMELY LOW CONCENTRATIONS OF URANIUM, ESPECIALLY IN SMALL SAMPLES, ARE DIFFICULT TO MEASURE USING EXISTING TECHNOLOGY. FUTURE NRC PLANS TO CHARACTERIZE BIOAVAILABLE URANIUM FRACTIONS COMPRISING THE URANIUM BODY BURDEN WILL REQUIRE EVEN HIGHER SENSITIVITIES. HIGH SENSITIVITY TECHNOLOGY DEVELOPED FOR UR ...

    SBIR Phase I 1992 Nuclear Regulatory Commission
  10. High Voltage Package Encapsulants

    SBC: TEXAS RESEARCH INSTITUTE , AUSTIN, INC.            Topic: DMEA231003

    With significant strides being made on wide bandgap (WBG) semiconductor devices for high-power electronics, there is a concurrent need for packaging encapsulants with reliable long-term performance in a more rigorous operational environment. The WBG power devices are set to be fielded in electric vehicles, aircrafts, spacecrafts, and energy producing systems where working conditions can see temper ...

    SBIR Phase I 2023 Department of DefenseDefense Microelectronics Activity
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