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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Information Technology Enabled Treatment of Adolescent Depression

    SBC: VERITAS HEALTH SOLUTIONS, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): This SBIR application proposes development of an Information Technology Enabled Disease Management System for Treatment of Adolescent Depression (ITEMS-TAD). The need for this system innovation arises from the substantial costs that inadequately treated adolescent Major Depressive Disorder (MDD) has on the course of adolescent development and society as a whole ...

    SBIR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  2. CODA Assembly of Mutant Genes

    SBC: VERDEZYNE, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The general goal of this proposal is to assemble directed mutant gene sets quickly, cheaply, easily, and reliably. Mutant gene sets can share sub-assemblies, yielding savings of time, cost, and effort not possible if designed and assembled all as single genes. The approach is to build upon experience gained in Phase I, to extend and generalize methods of DNA de ...

    STTR Phase II 2009 Department of Health and Human ServicesNational Institutes of Health
  3. Cardiac Regenerative Therapy with Cyclin A2

    SBC: VentriNova, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): The morbidity and mortality due to cardiovascular disease is attributed to the lack of significant replicative potential of adult mammalian cardiomyocytes. Thus myocyte loss in response to ischemic injury typically results in scar formation and a decline of cardiac function that is usually irreversible. The cessation of myocyte proliferation is associated with ...

    STTR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  4. Medical Food Cocktail for Alzheimer's Disease

    SBC: AKESO HEALTH SCIENCES, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): More than 4.5 million Americans currently suffer from Alzheimer's Disease, a progressive neurodegenerative disease characterized by loss of memory, changes in personality, agitation, disorientation, loss of coordination, and finally, total loss of day-to-day functioning. Alzheimer's is a staggeringly expensive disease, costing the American economy more than 83 ...

    SBIR Phase II 2009 Department of Health and Human ServicesNational Institutes of Health
  5. Elastic biodegradable ureteral stent

    SBC: AKINA, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The objective of this Phase I study is to develop elastic, biodegradable ureteral stents that will degrade in the body within 2 weeks after a procedure. Current ureteral stents are made of non-degradable polymers and, unless they are permanent, have to be removed by second procedure, which requires further intervention on the patients. Biodegradable ureteral st ...

    SBIR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  6. Delayed Hydrogel Tissue Expander

    SBC: AKINA, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The objective of this Phase II study is to develop novel hydrogel-based tissue expanders that have delayed expansion with the property to be reshaped by the surgeon. Current tissue expanders either require external inflation or are immediately swelling potentially re-opening the surgical implant site. Also, no current tissue expander is re-shapable, reducing th ...

    SBIR Phase II 2009 Department of Health and Human ServicesNational Institutes of Health
  7. Diagnostic Influenza RT-PCR Array

    SBC: AKONNI BIOSYSTEMS INC            Topic: N/A

    DESCRIPTION (provided by applicant): Influenza viruses are highly contagious negative-sense RNA viruses cause approximately 114,000 hospitalizations and 20,000 deaths annually. Several drugs are approved by the US Food and Drug Administration (FDA) for treating influenza infections, but successful treatment depends on knowing the specific antigenic subtype and administering these drugs within the ...

    SBIR Phase II 2009 Department of Health and Human ServicesNational Institutes of Health
  8. Novel Small-molecule TNF-a Modulators as Chemoprotective Agents

    SBC: 21ST CENTURY THERAPEUTICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Cisplatin is a widely used cytotoxic agent with therapeutic activity against various tumors, but also with substantial side effects, including nephrotoxicity, hepatotoxicity and myelosuppression. Therefore, a chemoprotective agent which reduces the side effects of cisplatin without affecting it efficacy would have significant clinical benefit. Currently, amifos ...

    SBIR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  9. Electrochemical RT Activity Assay for Measuring HIV Load

    SBC: ALDERON BIOSCIENCES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): To address the urgent need for better treatment and diagnostic testing of HIV infected people in resource-limited settings, we propose in this Phase II SBIR to further develop an electrochemical testing system (eSystem) developed by Alderon Biosciences, Inc. for determinations of HIV viral load in clinical samples. Alderon's long-term goal is to produce, valida ...

    SBIR Phase II 2009 Department of Health and Human ServicesNational Institutes of Health
  10. High Performance Detectors for SPECT

    SBC: RADIATION MONITORING DEVICES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): High Performance Detectors for SPECT P.I.: Dr. Michael R. Squillante Abstract Single photon emission computed tomography (SPECT) is a powerful, noninvasive medical imaging modality that mathematically reconstructs the three dimensional distribution of a radionuclide throughout the body of a human patient or a research animal. Typically, the collected data are d ...

    SBIR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
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