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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Development of Site-specific Arg-GlcNAc Antibodies

    SBC: GlycoScientific, L.L.C.            Topic: 300

    Human pathogenic gram negative bacteriasuch as Escherichia coliEColiand Salmonella enterica cause millions of deathsthousands of fatalities and billions of dollars in medical expenses and lost wagesA critical process that enables these organisms to overcome the hosts immune response is the injection of proteins directly into infected mammalianhostcellsSome of these injected effectorsfunction as en ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  2. Detecting species-specific bacterial meningitis markers with iDDS probes

    SBC: GENETAG TECHNOLOGY, INC.            Topic: NCIRD

    Detecting species specific bacterial meningitis markers with iDDS probes Confidential PI Shafer David A PhD PROJECT SUMMARY Rapid and accurate molecular diagnostics assays empower physicians to make informed treatment decisions Meningitis may be caused by infection with microorganisms such as viruses gram negative GN and gram positive GP bacteria fungi or parasites Most frequently meningitis resul ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  3. Nitric Oxide Releasing Ultra Slippery Antibacterial Surfaces for Indewelling Catheter Applications

    SBC: inNOveta Biomedical LLC            Topic: ODCDC

    Although decades of research have been done to develop the ideal blood contacting catheters there still remains no long term solution that prevents infection and thrombosis As antibiotic resistant bacteria become more prevalent the traditional methods of treatment become more obsolete The proposed research is to combine the long term antibacterial efficacy of a silicone rubber S nitrosothiol based ...

    SBIR Phase I 2019 Department of Health and Human Services
  4. Advanced therapeutic for Parkinson's Disease

    SBC: Inhibikase Therapeutics, Inc.            Topic: 999

    Parkinsonandapos s DiseasePDis a progressive neurodegenerative disorder that affectsmillion patient in the U Sannually andtomillion people worldwidePD is characterized by disorders of movementwhich are caused by the progressive loss of dopamine neurons in the substantia nigra pars compactaSNpcand autonomic dysfunctionanxietydepressionsleep disorders and cognitive impairment that are due to the deg ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  5. SBIR Phase I: Aerial manipulation platform for rebar tying

    SBC: RotoYe LLC            Topic: EW

    The broader impact/commercial potential of this SBIR Phase I project is to reduce the time required to construct concrete bridges, improve job site safety relating to rebar installation, reduce costs related to bridge construction, and improve the overall health of ironworkers. Ironworkers face some of the highest rates soft tissue damage of the industrial occupations due the constant bending over ...

    SBIR Phase I 2019 National Science Foundation
  6. SBIR Phase II: Point-of-Care Patient Photography Integrated with Medical Imaging

    SBC: Camerad Technologies, LLC            Topic: SH

    The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase II project is the widespread adoption of an efficient and accessible technology to integrate patient photographs with radiology images to improve patient safety, increase healthcare efficiency, and reconnect radiologists with their patients. A successful commercialization outcome is this adoption leadin ...

    SBIR Phase II 2019 National Science Foundation
  7. Accurate and Rapid Measurement of Adsorption Capacity of Fly Ash in Concrete Mixtures

    SBC: PHOSPHORTECH            Topic: 171FH1

    Proposal title: Accurate and Rapid Measurement of Adsorption Capacity of Fly Ash in Concrete Mixtures Interference of unburned and activated carbon in fly ash with air-entraining admixtures (AEAs) in fresh concrete mixtures is a major concern in the concrete industry. Therefore, a rapid and accurate measurement of adsorption capacity of fly ash is of great interest to this industry. In Phase I, ...

    SBIR Phase II 2018 Department of Transportation
  8. Developing pan lyssavirus beta actin real time RT PCR assays for rabies diagnostics

    SBC: CyanVac LLC            Topic: ODCDC

    Rabies is a deadly zoonotic disease caused by rabies virusRABVand other lyssavirusesAnnuallyrabies causes approximatelyhuman deaths worldwideThe only widely accepted diagnostic test is the direct fluorescent antibodyDFAtestWhile rapid and sensitivethe DFA test requires expensivehighquality reagents and equipmentalong with trained diagnosticiansThese factors present economic and logistical barriers ...

    SBIR Phase I 2018 Department of Health and Human Services
  9. Topic 376: Non-Invasive Subtyping of Aggressive Tumor and Its Environment- Moonshot

    SBC: INLIGHTA BIOSCIENCES L.L.C.            Topic: NCI

    Generation of high-resolution 3D anatomic and dynamic images without exposing patients to ionizing radiation renders MRI the preferred imaging modality for the detection of tumor extent and treatment response to neo-adjuvant and adjuvant medical therapies. The goal of this proposal is to develop a non-invasive, in vivo imaging-based platform that can repeatedly generate three-dimensional molecular ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  10. Topic 373: Exonuclease Time-of-Flight for the Low-Cost, Rapid Identification of Methylated RNA Single Molecules

    SBC: Digital Nanogenetics LLC            Topic: NCI

    There is growing interest in the study of RNA modifications and its potential role(s) in many physiological abnormalities, such as modulating many processes associated with cancer development and progression. While RNA sequencing (RNA-seq) using short-read nextgeneration sequencing (NGS) have proven to be a useful tool for identifying specific RNA modifications, there still remains technical chall ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
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