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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Oral Dissolvable Strips (ODS) as new pediatric and adult delivery mode of therapy for latent tuberculosis

    SBC: OAK THERAPEUTICS INC            Topic: NIAID

    PROJECT SUMMARY Tuberculosis (TB) remains one of the major sources of mortality from infectious diseases worldwide. In 2021 an estimated 6.4 million were newly diagnosed with TB globally, approximately 10.6 million fell ill from it, and 1.4 million died from the disease. Of those who died from the disease, 54% were men, 32% women, and 14% were children aged lt15 years. TB is also a leading cause o ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  2. ADEPT-STAR therapy for high risk neuroblastoma

    SBC: EXPRESSION THERAPEUTICS, LLC            Topic: 100

    PROJECT SUMMARY Cancer remains a primary health concern despite significant advancements in treatment. In the past decade, cell and gene (CandG) therapies along with immuno-oncology (I-O) therapies have transformed treatment expectations by extending cancer free survival and complete remissions. Despite these remarkable successes, they are limited to a subset of cancers and many significant challe ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  3. Tumor Monorail Device for Serial Glioblastoma Biopsy

    SBC: EXVADE BIOSCIENCE INC            Topic: 102

    Project Summary/Abstract Glioblastoma (GBM) is one of the most common and deadliest form of malignant brain tumors, with median patient survival of 12-15 months and five-year survival of less than 5%. The current standard of therapy for GBM comprises surgical resection then radiation and chemotherapy. However, due to the heterogeneity and invasive nature of GBM tumor cells there is a high rate (~8 ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  4. A novel driving coach app for older adults with cognitive impairment

    SBC: Minnesota HealthSolutions Corporation            Topic: NIA

    The goal of the proposed project is to develop an app for older adult drivers that combines feedback based on actual driving behavior with a dynamic and escalating modality of personal feedback and coaching designed for persons with Alzheimer’s disease (AD), Alzheimer’s disease related dementias (ADRD), or cognitive impairment. This app will be specifically designed and tested for older adult ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  5. Functionalized Multi-Modal Tetrode Arrays for Real-Time, Site-Specific Neurochemical Monitoring

    SBC: Pinnacle Technology, Inc.            Topic: 101

    ABSTRACT The goal of this proposal is to develop a multimodal, multianalyte sensor system including wired and wireless electronics and software. This new suite of tools will enable simultaneous recording of amperometric sensors (glutamate, glucose, lactate, choline, and/or oxygen), electrophysiology, and fast-scan cyclic voltammetry (biogenic amines) in conscious, freely moving rodents. The propos ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  6. Development of a Piezoelectric Intramedullary Nail for Enhanced Fracture Healing

    SBC: EVOKE MEDICAL LLC            Topic: NIAMS

    PROJECT SUMMARY The objective of this Phase I SBIR is to develop a modular piezoelectric intramedullary nail for enhance fracture healing and post-operative data collection. Evoke Medical’s core technology is to create human- powered implantable devices that utilize piezoelectric materials to generate load-induced power. That power can then be used for various purposes: electrical stimulation of ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  7. Nitric oxide Releasing Ultra-Slippery Antibacterial Surfaces for Urological Catheter Applications

    SBC: NYTRICX INC            Topic: 400

    Abstract Urinary catheters are one of the most widely used medical devices in a hospital setting and are expected to only increase in growth due to the aging population. Out of all the various biomedical devices that are frequently used in a clinical setting, urinary catheters are associated with the largest portion of medical complications related to infection. Catheter associated urinary tract i ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  8. Engineered Pan-Specific Reagents for N-Glycan Detection and Enrichment

    SBC: GLYCOSENSORS AND DIAGNOSTICS, LLC            Topic: 100

    PROJECT SUMMARY Glycans play crucial roles in nearly every aspect of biological processes, and their distinct properties make them appealing as disease biomarker targets. However, due to their highly branched and variably linked nature, glycans pose a challenge for detection, purification, and structural analysis. Although advanced analytical techniques and instrumentation have been developed that ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  9. Allogeneic BAFF Ligand Based CAR T-Cells as a Novel Therapy for Systemic Lupus Erythematous

    SBC: LUMINARY THERAPEUTICS, INC.            Topic: NIAID

    Abstract Systemic lupus erythematosus (SLE) is a complex, chronic autoimmune disease with no cure which affects 1.5 million Americans. SLE is a rheumatic disease which can lead to severe organ dysfunction, including end stage renal disease. Autoreactive B cells have emerged as primary drivers of the disease and the presence of anti-nuclear antibodies is a biomarker for diagnosis. Therapies targeti ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  10. The Rapid-Production of the High-Performance and Affordable Cadmium Telluride and Cadmium Zinc Telluride for Medical Imaging Applications.

    SBC: RADIATION DETECTION TECHNOLOGIES, INC.            Topic: NIBIB

    1 The high spatial-resolution and energy-resolution of cadmium zinc telluride (CZT) and cadmium telluride2 (CdTe), compared to that of scintillators, offers superior image quality in Nuclear medicine and X-ray3 imaging applications, i.e. SPECT, PET, CT, Bone Densitometry, Oncology, Dental imaging, Airport4 security, etc. CZT and CdTe remain the desired choice for room-temperature radiation detecti ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
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