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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. BPN Safety and Cognitive Effect in Young and Elderly Subjects

    SBC: TETRA DISCOVERY PARTNERS, INC.            Topic: NIA

    Project Abstract Tetra Discovery Partners is seeking Phase II SBIR funding for a multiple ascending dose human Phase clinical trial of BPN to evaluate safety tolerability pharmacokinetic and cognitive profile in healthy young and elderly male and female subjects BPN is a first in class phosphodiesterase D negative allosteric modulator PDE D NAM that targets the protein kinase A ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  2. Sustained release gel enabling one stage treatment of prosthetic joint infection

    SBC: SONORAN BIOSCIENCES, INC.            Topic: NIAMS

    Principal Investigator Overstreet Derek J Abstract Sonoran Biosciences Inc SBIR PAR Direct Phase II Prosthetic joint infections PJIs are especially costly requiring two surgeries at a cost of approximately $ per case to treat more than hip and knee replacement infections each year The near term outlook in this area is bleak with the number of infections growing ov ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  3. Microfabricated Cochlear Electrode Array

    SBC: MEMStim LLC            Topic: NIDCD

    Project Summary Abstract Current cochlear implants while beneficial in their use are limited in their capabilities by hand assembly of the electrode arrays This tedious manufacturing method is very costly extremely labor intensive and inadequate in implementing new technologies for improving speech recognition and music appreciation A superior alternative to hand assembly is microfabricati ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  4. HLS Hand held advanced functional imager for assessing local tissue oxygenation

    SBC: WASATCH PHOTONICS, INC.            Topic: NHLBI

    Summary We believe that our project is responsive to the HLS Small Business Topic of Special Interest for NHLBI Fiscal Year Here we will develop commercialization ready advanced functional imager to assess red blood cell RBC transfusion We successfully finished Phase I by developing the device s prototype and testing its functionality in the proof of principle experiments in scatter ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  5. SYSTEMIC RADIONUCLIDE THERAPY TARGETED TO VEGF RECEPTORS IN TUMOR VASCULATURE

    SBC: SIBTECH, INC.            Topic: NCI

    The overall goal of this collaborative project between SibTech Inc PI Backer J and Johns Hopkins University PI Pomper M is clinical development of efficient and cost effective anti angiogenic Lu radiopharmaceutical scV Lu for VEGF receptor mediated targeting of angiogenic tumor vasculature Current very expensive anti angiogenic compounds induce transient regression of tumor vascula ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  6. IGF OT IGF BASE AWARD STANDARDIZED RECHARGEABLE ELECTRONIC NICOTINE DELIVERY SYSTEM POP MARCH THROUGH NOVEMBER N DA EXTEND THE PERIOD OF PERFORMANCE FOR NO ADDITIONAL

    SBC: NJOY Inc.            Topic: NIDA

    Not Available

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  7. IGF OT IGF Topic Phase I SBIR Predictive Biomarkers of Adverse Reactions to Prostate Cancer Radiotherapy

    SBC: L2 DIAGNOSTICS, LLC            Topic: NCI

    Not Available

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  8. IGF OT IGF Circulating nucleic acid based nanowell label free array technology in cancer

    SBC: DETROIT R & D, INC.            Topic: NCI

    Not Available

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  9. IGF OT IGF Topic Phase I SBIR Defining normal tissue and tumor biomarkers of radiosenstivity to detect treatment

    SBC: MIRA DX, Inc.            Topic: NCI

    Not Available

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  10. Engineering a phosphotyrosyl-tRNA Synthetase

    SBC: AXIOMX INC            Topic: 300

    DESCRIPTION provided by applicant Although tyrosine phosphorylation is an important controlling element in cell signaling no tRNA suppressor for phosphotyrosine pTyr incorporation has yet been made We propose to use directed molecular evolution of several aminoacyl tRNA synthetases aaRSs to identify mutations that enable binding of pTyr to the aaRS Specifically ATP molecules will be att ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health

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