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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

  1. INTEGRIN CYTODOMAIN ANTI-THROMBOTICS

    SBC: COR THERAPEUTICS, INC.            Topic: N/A

    DESCRIPTION: (Investigator's abstract) The key element in the "final common pathway" leading to stable platelet aggregation is fibrinogen binding to the platelet integrin, alplaIIbbeta3. alphaIIbbeta3 inhibitors, that prevent platelet aggregation and subsequent thrombus formation by blocking the interaction of alphaIIbbeta3 with its ligands, have proven e ...

    SBIR Phase II 2001 Department of Health and Human Services
  2. Ampakines in Schizophrenia

    SBC: CORTEX PHARMACEUTICALS, INC.            Topic: N/A

    N/A

    SBIR Phase II 2001 Department of Health and Human Services
  3. HIGH PERFORMANCE BIOSENSOR ELECTRODE MATERIALS

    SBC: CYGNUS, INC.            Topic: N/A

    N/A

    SBIR Phase II 2001 Department of Health and Human Services
  4. TUMOR CELL PURGING USING FLUORESCENT ANTIBODIES

    SBC: CYNTELLECT, INC.            Topic: N/A

    DESCRIPTION (applicant's abstract): Autologous hematopoietic stem cell (HSC) transplantation is used for treatment of many cancers. However, contaminating tumor cells within HSC harvests are problematic since their contribution to disease relapse has been unambigiously established through gene-marking studies. Therefore, technology that reliably eliminates dete ...

    SBIR Phase II 2001 Department of Health and Human Services
  5. A Mini-Ad Vector for Treatment of Factor VIII Deficiency

    SBC: GENSTAR THERAPEUTICS            Topic: N/A

    N/A

    SBIR Phase II 2001 Department of Health and Human Services
  6. Development of a MSP1-p42 Subunit Vaccine for Malaria

    SBC: Hawaii Biotech, Inc.            Topic: N/A

    DESCRIPTION (provided by the applicant): Malaria is a tropical parasitic disease that poses a significant health threat to much of the world. Each year, approximately 500 million people become infected and more than 2 million die. There is a great need to control the spread of this disease. One of the main focuses of malaria vaccine development has been the on use o ...

    SBIR Phase II 2001 Department of Health and Human Services
  7. HIV/AIDS Prevention for Women in Drug Treatment

    SBC: HEALTHCARE EDUCATION ASSOCIATES            Topic: N/A

    DESCRIPTION (provided by applicant): The overall objectives of the proposed educational program are to increase women's: 1) knowledge of HIV/AIDS transmission and prevention; 2) perception of risk; 3) perceived self-efficacy in adopting risk reduction strategies; 4) skills in a) negotiating safer sex and b) using condom ...

    SBIR Phase II 2001 Department of Health and Human Services
  8. Antimicrobial agents directed against L11/23S rRNA

    SBC: IBIS BIOSCIENCES, INC.            Topic: N/A

    The antibacterial drug thiostrepton binds to the L11 binding site of the 23S rRNA in bacterial ribosomes and prevents protein synthesis, yet is clinically unattractive due to poor pharmacokinetic properties. We have discovered in our Phase I work a number of compounds that work by a mechanism similar to that of thiostrepton. The related structural features of these compounds suggest that a compell ...

    SBIR Phase II 2001 Department of Health and Human Services
  9. Feasiblity Analysis of a Clinical Electroporation System

    SBC: ICHOR MEDICAL SYSTEMS, INC.            Topic: N/A

    N/A

    SBIR Phase II 2001 Department of Health and Human Services
  10. A Novel Electroporation System for Gene Therapy with EPO

    SBC: ICHOR MEDICAL SYSTEMS, INC.            Topic: N/A

    N/A

    SBIR Phase II 2001 Department of Health and Human Services

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