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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Optimized Platforms for Proper Glycosylation and Sialylation of Recombinant Human Butyrylcholinesterase (rBChE)

    SBC: ECHELON BIOSCIENCES, INC.            Topic: CBD192007

    Organophosphorus (OP) toxins and chemical warfare agents (CWA) are active nerve agents posing significant hazard for both soldiers and civilians. Butyrylcholinesterase (BChE) is a safe and effective bioscavenger that detoxifies OP and CWAs when injected either prophylactically or post-exposure; but a major technical problem has been producing a recombinant form of BChE with acceptable properties f ...

    SBIR Phase I 2020 Department of DefenseOffice for Chemical and Biological Defense
  2. Self-contained Equipment Decontamination System (SCEDS)

    SBC: Integrated Solutions for Systems, Inc.            Topic: CBD192002

    The processes and systems required to decontaminate personnel have received much attention and several effective systems exist. However, decontamination of sensitive equipment, without damage or performance degradation, is a significantly different problem that has not been adequately solved. The wide variety of electronics, fabrics and structural materials together with the infinite variations in ...

    SBIR Phase I 2020 Department of DefenseOffice for Chemical and Biological Defense
  3. Non-Invasive Monitoring of Changes in Intracranial Pressure Due to Infections in the Central Nervous System

    SBC: Fenix Research Corporation            Topic: CBD192005

    Infections of the central nervous system (CNS) are associated with brain swelling and increased cerebral blood volume, as well as focal cerebral perfusion deficits, variable levels of cerebral blood flow and cerebral vasculitis. The net result is increased intracranial pressure (ICP) along with significant risk of brain tissue herniation and ischemic syndromes. ICP monitoring is critical in the ma ...

    SBIR Phase I 2020 Department of DefenseOffice for Chemical and Biological Defense
  4. Development of a Non-invasive Negative Ophthalmodynamometer Capable of Measuring Intracranial Pressure in Humans

    SBC: Equinox Ophthalmic, Inc.            Topic: CBD192005

    Measurement of intracranial pressure (ICP) is essential in the diagnosis and management of numerous life threatening conditions. All current methods used clinically to measure ICP are invasive and require direct access to the cerebrospinal fluid giving them a significant side effect profile. The ability to measure ICP non-invasively would be a major milestone for patients. Spontaneous venous pulsa ...

    SBIR Phase I 2020 Department of DefenseOffice for Chemical and Biological Defense
  5. Development of Small Molecule Therapeutics for Emerging Viral Agents

    SBC: ARISAN THERAPEUTICS INC            Topic: CBD192006

    Arenaviruses comprise a diverse group of Old (Africa) and New World (Americas) species. Several species are associated with hemorrhagic fever (HF) with case-fatality rates as high as 30%. Arenaviruses infection typically occurs via the mucosal route through contact with excretions of an infected rodents although direct human-to-human transmission may occur in clinical settings. Lassa arenavirus en ...

    SBIR Phase I 2020 Department of DefenseOffice for Chemical and Biological Defense
  6. Development of Small Molecule Therapeutics for Emerging Viral Agents

    SBC: ARISAN THERAPEUTICS INC            Topic: CBD192006

    Ebolavirus species including Zaire (EBOV), Sudan (SUDV) and Bundibugyo (BDBV) are responsible for severe hemorrhagic fever outbreaks with high case fatalities in Africa. Weaponized pathogens present an additional threat to the health protection of the warfighter and first-generation prophylactic and therapeutic medical countermeasures (MCMs) may prove inadequate in biodefense settings. Ebolaviruse ...

    SBIR Phase I 2020 Department of DefenseOffice for Chemical and Biological Defense
  7. A Multi-Branch Network for Automated VNIIRS Assessment of Motion Imagery

    SBC: TOYON RESEARCH CORPORATION            Topic: NGA191003

    Due to the lack of consistency in existing automated methods for assigning VNIIRS levels to motion imagery, and the overwhelming human resources required to manually assign levels, a new method of automated/semi-automated VNIIRS assessment is needed. In recent years, advancements in deep learning have provided solutions to previously intractable computer vision problems. In many cases, automated d ...

    SBIR Phase I 2019 Department of DefenseNational Geospatial-Intelligence Agency
  8. Multi-hop processing for OTHR range extension

    SBC: DECIBEL RESEARCH, INC.            Topic: NGA191011

    The development of sophisticated anti-access/area denial (A2/AD) capabilities by our adversaries requires us to develop long range capabilities to mitigate this A2/AD threat. Extending the range of Over The Horizon Radars beyond their conventional single hop operating mode will potentially provide coverage out to 10000 km and beyond. We propose combining existing state-of-the art HF radar ray prop ...

    SBIR Phase I 2019 Department of DefenseNational Geospatial-Intelligence Agency
  9. Faster Optical Modem for Underwater Data Acquisition

    SBC: SONALYSTS INC            Topic: NGA182001

    To address NGA’s requirements, Sonalysts’ team of world-class experts in underwater optical communication proposes development and implementation of the Precision Optical Navigation Transceiver for Undersea Systems (PONTUS). PONTUS will transfer navigation information from an Underwater Navigation Beacon (UNB) to an Unmanned Undersea Vehicle (UUV) in an electromagnetic-spectrum-denied (e.g., G ...

    SBIR Phase I 2019 Department of DefenseNational Geospatial-Intelligence Agency
  10. Faster Optical Modem for Underwater Data Acquisition

    SBC: SA PHOTONICS, LLC            Topic: NGA182001

    SA Photonics’ Optical Navigation and Ranging (ONAR) system is an interrogative system that operate underwater in wavelength range of blue/green (450-540 nm) and enables navigational correction to IMU based dead reckoning navigation. The location based beacons are battery operated and have operational life span of over one year. The system is designed to operate in on demand burst mode so that no ...

    SBIR Phase I 2019 Department of DefenseNational Geospatial-Intelligence Agency
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