Award Data

Methods for interconversion between cell types (cellular reprogramming) are currently discovered through resource intensive trial and error. Experiments may test a multitude of transcription factors to identify correct combinations that influence cell fate. In addition, reprogramming approaches commonly use stem cell intermediates such as induced pluripotent stem cells (iPSCs), which are generated ...

Triton Systems will develop a novel approach to field-based disease and biochemical diagnostics through innovative use of extremely low cost bioanalytical devices.The proposed platform will provide a low cost, portable, and reliable diagnostic test for on-site use in austere and resource-limited environments.The devices will be highly durable, rugged, and easy to use without user-induced variation ...

In this proposal we support the development of a hypoxia test battery by designing and developing a domain general tool suite for processing, synchronizing, and evaluating data from cognitive, behavioral, and physiological measures.The proposed Griffon Tool Suite addresses many of the practical requirements demanded by a flexible test battery. The effort falls into three major thrusts.First, we pr ...

Adverse physiological events (PEs) have plagued warfighters piloting military aircraft, in particular PEs involving hypoxia and cockpit cabin decompression. Though there has been a large variety of research performed in trying to understand the problems and why theyre caused, there are inefficiencies due to the lack of standardized cross-laboratory protocols, procedures, and metrics. To address th ...

Increased workloads and operational pressures can degrade human analysts cognitive performance, jeopardizing their ability to safely and effectively carry out mission-critical tasks. To avoid overload and maximize the potential of human operators, a method for conducting real-time evaluation of cognitive state, combined with means to dynamically enhance performance, is required. Novel technologies ...

Currently networks are not taking advantage of the inherent benefits of high multi-beam directional networking. For example, the current MADL implementation simply daisy chains the nodes in the network creating multiple single points of network failure (of course retaining self-healing properties.) The Fuse Directional Cross-Layer Networking Solution (DCLNS) optimized architecture features a robus ...

Combat casualty handoffs are critical communication moments during which responsibility for the patient and important casualty information is transferred between providers. The nature of these handoffs requires specialized training, for which no standardized framework currently exists. The proposed effort aims to develop a capability, compatible with current DoD systems, that provides caregivers w ...

This proposal is to develop a Handoff Training for Combat Casualty Care (HTC3) Framework.Training is the crux of the handoff problem today. Patient handoffs are a crucial part of casualty care, both in military and civilian environments; and today handoffs are being performed in less than optimal fashion, with ineffective communications accounting for 80% of the handoff errors. Our new HTC3 Framew ...

Because of rising demand for human analysts and more efficient processing of increasingly large and challenging amounts of intelligence, human limitations on mental workload, cognitive fatigue, and attentionor task engagement, need to be accurately monitored in real-time in order to provide sensitive detection of impaired cognitive states. It is a challenge to continuously monitor these cognitive ...

The widespread use of Aqueous Film Forming Foams (AFFF) at DOD facilities for firefighting, training, and fire suppression systems has resulted in numerous contamination sites. The perfluoroalkyl (PFA) compounds used in the AFFF, such as perfluoroalkyl sulfonates (PFOS) and perfluoroalkyl carboxylic acids (PFOA) are extremely stable in the environment and have been shown to be resistant to typical ...