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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

Displaying 61 - 70 of 23070 results
  1. Preclinical development of AST-004 for astrocyte-mediated treatment of TBI.


    PROJECT SUMMARY Traumatic brain injuriesTBIincluding concussionsare an area of significant unmet need with no approved therapeutics and a national burden of$billion annuallyTBI is the global leading cause of post injury death and disabilityand overmillion Americans sustain a TBI each yearThe tremendous incidence and long term consequences of TBI highlight the considerable epidemic at handand the n ...

    SBIR Phase II 2018 Department of Health and Human Services
  2. A game-based intervention for Opioid Use Disorder

    SBC: Pear Therapeutics, Inc.            Topic: NIDA

    Abstract Summary Opioid Use DisorderOUDis a serious public health concern that affectedmillion Americans and was responsible for a record number of overdose deaths inRemarkablyof individuals with OUD do not receive treatmenteven though OUD can be successfully treated when cognitive behavioral therapy is combined with buprenorphine pharmacotherapyA major barrier to receiving care is limited access ...

    SBIR Phase II 2018 Department of Health and Human Services
  3. Next Generation Drugs for Bipolar Depression and Maintenance

    SBC: Blue Oak Pharmaceuticals, Inc.            Topic: 101

    Project SummaryThe goal of this program is to discover the next generation of drugs for bipolar depression and maintenanceBPDa brain disorder that affectsmillion adult AmericansExisting drug classes are relatively ineffective and very few new modes of actionMOAshave been developed in the pastyearsThis is duein partto the lack of predictive preclinical BPD disease models and the biopharma industry ...

    SBIR Phase I 2018 Department of Health and Human Services
  4. Novel Small Molecule Therapeutics Inhibiting Zika Virus Infection

    SBC: MICROBIOTIX, INC.            Topic: NIAID

    Abstract Zika virusZIKVa flavivirusis the cause of the recent pandemic of infections across both North and South America often associated with serious neurological damageincluding congenital microcephaly in newborns and Guillain Barrsyndrome in adultsAccording to the CDCalmostof women who were infected with ZIKV during pregnancy give birth to babies with severe birth defectsincluding microcephaly ...

    SBIR Phase I 2018 Department of Health and Human Services
  5. Additive Manufacturing of a Conformal, Wideband Array for Attritable Aircraft Platforms (1000-456)

    SBC: SI2 TECHNOLOGIES, INC            Topic: AF171115

    SI2 Technologies, Inc. (SI2) proposes to enable wideband, conformal, dual-polarized phased array capability for geometrically constrained platforms, such as attritable aircraft and tube-launched munitions.SI2s AM arrays can be designed to conform to the outer mold line of those vehicles, minimizing aerodynamic drag and offering a SWAP-C advantage over conventional arrays.To meet this objective, SI ...

    SBIR Phase II 2018 Department of DefenseAir Force
  6. MIRK to Improve ASW & Reduce False Alarms

    SBC: PROMETHEUS INC            Topic: N093198

    We will extend development of the advanced signal processing algorithmMaterial Identification Reflectivity Kernel (MIRK) with the aim oftransitioning it to the ARCI AxB program and integration into the AN/SQS-53CActive Hull Mounted Sonar System. Prometheus will develop appropriatesystem-specific compensation algorithms, decision architecture and processingstream computer code to integrate MIRK int ...

    SBIR Phase II 2018 Department of DefenseNavy
  7. An eddy covariance system for simultaneous flux measurements of total reactive nitrogen, ammonia, and nitrogen oxides (NOx).

    SBC: Aerodyne Research, Inc.            Topic: 84

    SummaryNitrogen balance plays a critical role in agricultural food security and biodiversity. While some nitrogen addition, such as fertilization, is highly beneficial to agriculture, too much can result in lower crop yields and plant loss. Air pollution can tip the nitrogen balance toward unhealthy soil and poor growing conditions and affect a plant's ability to cope with drought. Understandi ...

    SBIR Phase II 2018 Department of Agriculture
  8. Biobased BPA-Free Epoxy Coatings for Food and Beverage Applications

    SBC: VURONYX TECHNOLOGIES LLC            Topic: 88

    In this Phase II SBIR project, Vuronyx Technologies will investigatehigh performance BPA free epoxy coatings for food and beverage cans.Canning of foods and beverages in metal containers is extensively used for food preservation and storage. The protective coating applied on the inside surface of the food/beverage container should be safe for food contact, have excellent adhesion to the substrate, ...

    SBIR Phase II 2018 Department of Agriculture
  9. An Intraoperative Guidance Platform for Radio Frequency Ablation

    SBC: NE Scientific, LLC            Topic: 102

    Project SummaryThe objective of this proposed research program is to develop a platform for planning and guidance during Radio Frequency AblationRFARFA is a thermally mediated ablation techniquewhere an applicator carrying one electrode is inserted into tumors percutaneouslyor via laparoscopyor open surgical approachesRadio FrequencyRFenergy is applieddenaturating and coagulating tissues in a volu ...

    SBIR Phase II 2017 Department of Health and Human Services
  10. Compact Energetic Charged Particle Sensor

    SBC: Assurance Technology Corporation            Topic: AF171067

    The space environment has a significant and deleterious effect on US space assets.Spacecraft anomalies that lead to effects ranging from data dropouts, decrease in capability, mission degradation and mission failure have occurred over the years. We propose to develop a Compact Energetic Charged Particle sensor (C-ECP), compatible with the limited resources of 100-kg class satellites, that will pro ...

    SBIR Phase II 2018 Department of DefenseAir Force

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