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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Antibody targeting of ADAM8 for treatment of triple-negative breast cancer
SBC: ADECTO PHARMACEUTICALS, INC. Topic: NCITriple negative breast cancersTNBCsaccount forof breast cancer deaths and lack targeted therapiesWe identified the non essentialcell surface protein ADAMas an important target on TNBCADAMis present inof primary TNBCsandof all breast cancer patient derived metastasesbut absent in normal breast tissuesHigh ADAMmRNA levels correlate with poor patient outcomeThe ADAMMetalloproteinaseMPand DisintegrinD ...
SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health -
NAAA Inhibition for Pain and Inflammation
SBC: NeoKera, LLC Topic: 103PROJECT SUMMARY Pain management is a significant unmet medical needPalmitoylethanolamidePEAis an endogenous analgesic substance that plays crucial roles in the peripheral control of pain and inflammationIts biological actions are terminated by the cysteine hydrolaseN acylethanolamine acid amidaseNAAADuring the Phaseof the present SBIRapplicationwe have developed the first class of potentselective ...
SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health -
New-Generation of Fluorescently-Labeled Charge-Neutralized Oligonucleotides as Probes for the Detection and Quantification of MicroRNAs and Oligonucleotide-Based Therapeutics in Biological Samples
SBC: ZATA PHARMACEUTICALS, INC. Topic: 400ABSTRACTTo datemore thanmicroRNAsmiRshave been identified in humansAberrant miRs expression has been associated with many human diseasesand especially with cancerThereforeearly detection and quantitation of those miRs can have a significant impact on patientsandaposoutcome and survival rateThe utility of miRs as potential clinical and diagnostic tools is severely limited by the availability of sim ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Motor Unit Drive (MU Drive) for Prosthetic Control
SBC: ALTEC, INC Topic: NICHDThe proposed Phase II SBIR project will develop a unique motor unit (MU) based control system (MU Drive™) that uses neural firings measured noninvasively and in real-time to drive an upper-limb prosthesis. Our Phase I effort successfully proved the technical merit and feasibility by demonstrating that MU firings can be measured from surface myoelectric recordings in real-time and used to provide ...
SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health -
Blood Flow Velocimetry Using Digital Subtraction Angiography
SBC: RADIATION MONITORING DEVICES, INC. Topic: NHLBIPROJECT SUMMARYDiseases in the vascular system are still the leading cause of mortality and morbidity in developed countries despite considerable therapeutic progress in recent yearsBlood flow velocity provides critical information needed for the diagnosis of vascular diseasesplanning of interventional surgery treatmentand monitoring of endovascular treatment of brain arteriovenous malformationsTh ...
SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health -
Cell Engineering Platform for Red Blood Cell Mediated Treatment of Autoimmune Diseases
SBC: SQZ Biotechnologies Company Topic: NIBIBProject Summary Autoimmune diseaseswhich affect more thanmillion Americansarise when the immune system targets naturally occurring proteinsself antigensmounting a response against normal tissues and causing a disease stateCurrent therapies only treat the symptoms of the diseasewithout curing the underlying autoimmune conditiontypical treatments are limited to systemic immunosuppressive therapy tha ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Multimodal otoendoscope for non-invasive diagnosis for middle ear pathology
SBC: PHYSICAL SCIENCES INC. Topic: NIDCDProject Summary Abstract This proposal addresses the growing clinical need for non invasive diagnostic tools that can efficiently evaluate middle ear diseasesPhysical Sciences IncPSIin collaboration with the Massachusetts Eye and Ear InfirmaryMEEIproposes to develop a clinically viable multimodal otoendoscopic imaging instrument that can analyze middle ear morphologyfunctionand biochemical changes ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Micro-imaging catheters for high-resolution, image-guided, endovascular repair of brain aneurysms
SBC: GENTUITY LLC Topic: 103PROJECT SUMMARY This program will commercialize a high speedhigh resolutionneuroendovascular imaging platform that allows neurointerventionalists to directly visualize intravascular devices and their interaction with vessels during treatment of brain aneurysmsThe miniaturization of the design features of neurovascular stents and flow diverters has enabled an explosion of technologies available for ...
SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health -
A technology solution for peer-led Seeking Safety
SBC: LMN CONSULTING Topic: NIDAAbstractPeers are increasingly recognized as an important asset in healthcarePeer support is historically most prominent for substance use disorderSUDsuch as the world wide model of Alcoholics Anonymous and otherstep groupsYet for trauma and posttraumatic stress disorderPTSDthere have been few attempts at peer helpA major challenge of trauma peer groups is that they usually focus on telling the st ...
SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health -
A Genotype-Phenotype Archiving and Communication System
SBC: PhenoSolve LLC Topic: 172Despite major advances in genome sequencing and identification of the genetic basis of diseaseclinical use of genomic analysis is limited in part by the costs and coordination associated with correlating genome results with phenotypic findingsSegalClinicians are overwhelmed by the huge amounts of information needed to assess a genomeand laboratory scientists are hampered by getting sparse informat ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health