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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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New Broad-Acting Cell Wall Antibiotics for Biodefense
SBC: MAXTHERA, INC. Topic: N/ADESCRIPTION (provided by applicant): A bioterrorist arsenal is likely to include a broad spectrum of bacterial species including the Category A pathogens Yersinia pestis (plague), a Gram-negative species, and Bacillus anthracis (anthrax), a Gram- positive species. Broad-spectrum antibiotics are potentially the most valuable for biodefense because these agents can be used quickly even in the absenc ...
SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health -
A multimodal platform for Oral screening of COVID-19
SBC: InnoTech Precision Medicine, Inc Topic: NIDCROriginal Abstract A multimodal platform for Oral screening of COVID-19 The development of a rapid and reliable sensor system from readily available oral specimens is crucial for the screening and management of SARS-CoV-2 infection. Other than tests that require laboratory-scale instrumentation, the development of rapid tests can play a timely role in the management of an outbreak. Current rapid te ...
STTR Phase I 2021 Department of Health and Human ServicesNational Institutes of Health -
Assessing the commercial potential of high-density electrodes with single unit recording and stimulation capabilities.
SBC: Neural Dynamics Technologies LLC Topic: NIMHSF424 – Project Summary Understanding how the brain generates certain behaviors requires an understanding of the function of individual neurons in dynamical neural circuits. Currently, there are few technologies available however that allow researchers to record both the activity within a brain region, and between brain regions in the brains of awake, behaving animals. Recent advances in microel ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Rapid, Simple and Cost-Effective Detection of Human Cell Line Contamination
SBC: Nuprobe Usa, Inc. Topic: RSummary Cell line contamination and misidentification have dramatic repercussions in the field biomedical researchlargely contributing to the growing concerns about irreproducible results and posing a significant burden on the global biomedical research budgetWhile the general awareness about these issues has raised over the last yearscurrent authentication technologies such as short tandem repeat ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Clinical study of GMCI in Pancreatic Cancer
SBC: ADVANTAGENE, INC Topic: N/ADESCRIPTION (provided by applicant): Pancreatic adenocarcinoma is the fourth leading cause of cancer deaths in the US; with less than one-year median survival, it accounts for approximately 30,000 diagnoses and deaths per year. Multimodality therapy, including surgery, radiation and chemotherapy, have not made a significant impact on the outcome and serve mostly as palliation. Thus, new treatment ...
SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health -
Developing a Scalable Manufacturing Process for an Oral Bacteriophage Product that Prevents Cholera
SBC: PHAGEPRO, INC. Topic: NIAIDPROJECT SUMMARY Cholera is an acute and severe disease caused by the bacterium Vibrio cholerae that is spread primarily through contaminated water sources due to a lack of adequate sanitation infrastructure. The World Health Organization estimates that there are at least 3 million cases globally per year, 40 percent of which are spread through household transmission. Current prevention methods req ...
STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
All-optical electrophysiology in brain slice for drastically increased throughput
SBC: Q-State Biosciences, Inc. Topic: 101Project Summary Severe psychiatric disordersincluding schizophreniabipolar disorderand major depressive disorder are prevalentchronic and debilitating brain diseases that result in intense suffering and reduced quality of lifeThere is a profound lack of new medicines for psychiatric disorderswhich remain a major area of unmet medical needDiscovery of more effective therapies for mental illness has ...
SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Identification of Ebola Virus Entry Inhibitors
SBC: MICROBIOTIX, INC. Topic: N/ADESCRIPTION (provided by applicant): Ebola virus (EBOV) causes periodic outbreaks of severe viral hemorrhagic fevers in Africa with high mortality rates in infected patients. EBOV can be used in acts of bio-terrorism because of its highly infectious nature and stability in aerosolized form. It is classified as a Category A bioweapons agent by the Centers for Disease Control and Prevention (CDC). C ...
SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health -
Silencing cardiac-specific microRNAs to prevent pathological remodeling in conges
SBC: Virscio Inc Topic: NHLBIDESCRIPTION (provided by applicant): Heart disease remains the primary cause of morbidity and mortality in the industrialized world and continues to incur costs estimated at 30 billion per year, despite detailed understanding of the mechanisms governing cardiac function and contractility. MicroRNAs (miRNAs), a recently discovered family of tiny regulatory RNAs, act as negative regulators of gene ...
SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health -
Hyperpolarized 129-Xenon-based MRI Probes for Brain Injury
SBC: KOVOGEN Topic: N/ADESCRIPTION (provided by applicant): This proposal describes the development of hyperpolarized-129Xenon (HP-Xe)-based probes for magnetic resonance imaging (MRI) of two biomarkers of inflammation and brain injury, the peripheral benzodiazepine receptor (PBR) and the neurotrophic protein, S100B. Molecular imaging (MI) is an emerging discipline that tries to non-invasively visualize specific biomole ...
SBIR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health