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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. TECHNOLOGY FOR IMPROVING IN VITRO MAMMALIAN CELL CULTURE AND

    SBC: Microdrop/acorn            Topic: N/A

    N/A

    SBIR Phase I 1985 Department of Health and Human Services
  2. LASER MICROPOLARIMETRY

    SBC: Optra, Inc.            Topic: N/A

    IN THE PROPOSED PROGRAM WE WILL DEVELOP AN INSTRUMENT FOR MEASURING SMALL AMOUNTS OF TRANSIENT BIREFRINGENCE IN MICROSCOPIC BIOLOGICAL SAMPLES, AND WILL APPLY IT TO AN EXISTING MEASUREMENT REQUIREMENT IN THE AREA OF NEUROPHYSIOLOGY. THE PROPOSED LASER MICROPOLARIMETER WILL BE CAPABLE OF MEASURING SAMPLE BIREFRINGENCE WITH SENSITIVITY AT LEAST 100 TIMES GREATER THAN THAT OF CURRENTLY AVAILABLE TECH ...

    SBIR Phase II 1985 Department of Health and Human Services
  3. THE SYNTHESES OF 19 CHOLECYSTOKININ-OCTAPEPTIDE ANALOGUES ARE PROPOSED.

    SBC: Peptide Technolgies Corp.            Topic: N/A

    THE SYNTHESES OF 19 CHOLECYSTOKININ-OCTAPEPTIDE ANALOGUES ARE PROPOSED. THE PREPARATION OF THESE PEPTIDES WILL INVOLVE SOLID-PHASE TECHNIQUES AND PURIFICATION OF A NEW INSTRUMENT FOR COUNTER-CURRENT CHROMATOGRAPHY, THE HORIZONTAL FLOW-THROUGH COIL PLANET CENTRIFUGE. THE BINDING OF THESE PEPTIDES TO CHOLECYSTOKININ CENTRAL NERVOUS SYSTEM AND PANCREATIC RECEPTORS WILL BE DETERMINED. ADDITIONALLY, TH ...

    SBIR Phase I 1985 Department of Health and Human Services
  4. PLURONIC 68, A COPOLYMER OF ETHYLENE OXIDE-PROPYLENE OXIDE, IS THE SURFACTANT MOST THOROUGHLY STUDIED FOR STABILIZING PERFLUOROCHEMICAL EMULSIONS USED AS INTRAVENOUS OXYGEN TRANSPORT FLUIDS; IT EXHIBITS ADVANTAGEOUS CHEMICAL AND EMULSIFICATION PROPERTIES

    SBC: Phasex Corporation            Topic: N/A

    PLURONIC 68, A COPOLYMER OF ETHYLENE OXIDE-PROPYLENE OXIDE, IS THE SURFACTANT MOST THOROUGHLY STUDIED FOR STABILIZING PERFLUOROCHEMICAL EMULSIONS USED AS INTRAVENOUS OXYGEN TRANSPORT FLUIDS; IT EXHIBITS ADVANTAGEOUS CHEMICAL AND EMULSIFICATION PROPERTIES BUT TESTS HAVE SHOWN SOME LOTS OF THE POLYMER TO BE MILDLY TOXIC. MANY TYPES OF PURIFICATION AND FRACTIONATION PHILOSOPHIES, E.G., ADSORPTION (BO ...

    SBIR Phase I 1985 Department of Health and Human Services
  5. THE OBJECTIVE OF THIS RESEARCH PROJECT IS TO ANALYZE, IN DETAIL, THE INTERACTION OF PULSED CO2 LASERS WITH BIOLOGICAL TISSUE.

    SBC: Physical Sciences Inc.            Topic: N/A

    THE OBJECTIVE OF THIS RESEARCH PROJECT IS TO ANALYZE, IN DETAIL, THE INTERACTION OF PULSED CO2 LASERS WITH BIOLOGICAL TISSUE. EMPHASIS WILL BE PLACED ON DETERMINING THE MOST IMPORTANT PARAMETERS WHICH CONTROL THE DEPTH AND RATE OF INCISION AND DAMAGE TO THE SURROUNDING TISSUE. TWO TISSUE DAMAGE MECHANISMS WILL BE INVESTIGATED: THERMAL AND PRESSURE EFFECTS. THE FORMER RESULTS FROM THE RESIDUAL ENER ...

    SBIR Phase I 1985 Department of Health and Human Services
  6. PRELIMINARY OBSERVATIONS INDICATE THAT OBJECTIVE LUNG SOUND ANALYSIS PROVIDES IMPORTANT NONINVASIVE DIAGNOSTIC INFORMATION OF COMMON PULMONARY CONDITIONS.

    SBC: Pulmonology Services, Inc.            Topic: N/A

    PRELIMINARY OBSERVATIONS INDICATE THAT OBJECTIVE LUNG SOUND ANALYSIS PROVIDES IMPORTANT NONINVASIVE DIAGNOSTIC INFORMATION OF COMMON PULMONARY CONDITIONS. SUCH ANALYSIS CAN ALSO BE USED TO VALIDATE THE ACCURACY OF OBSERVERS USING STETHOSCOPES AND IMPROVE THE LEARNING PROCESS. THIS TYPE OF ANALYSIS CAN NOW BE READILY PERFORMED WITH A STETHOGRAPH, AN INNOVATIVE DEVICE THAT MAKES VISUAL DISPLAYS OF T ...

    SBIR Phase I 1985 Department of Health and Human Services
  7. THE PURPOSE OF THIS PROJECT IS TO DEVELOP INSTRUMENTS AND PROCEDURES FOR THE USE OF EMPLOYEE ASSISTANCE PROGRAM (EAP) PRACTITIONERS IN DIAGNOSING THE PSYCHOLOGICAL, PHYSICAL, SOCIAL, AND OTHER PROBLEMS AND NEEDS OF EMPLOYEES WITH DRUG PROBLEMS, AND

    SBC: Rci Inc.            Topic: N/A

    THE PURPOSE OF THIS PROJECT IS TO DEVELOP INSTRUMENTS AND PROCEDURES FOR THE USE OF EMPLOYEE ASSISTANCE PROGRAM (EAP) PRACTITIONERS IN DIAGNOSING THE PSYCHOLOGICAL, PHYSICAL, SOCIAL, AND OTHER PROBLEMS AND NEEDS OF EMPLOYEES WITH DRUG PROBLEMS, AND MAKING APPROPRIATE REFERRALS TO TREATMENT AGENCIES. TECHNIQUES WILL ALSO BE DEVELOPED FOR EVALUATING TREATMENT RESOURCES, MATCHING CLIENT NEEDS TO RESO ...

    SBIR Phase I 1985 Department of Health and Human Services
  8. DEVELOPMENT OF INSTRUMENTS FOR ASSESSING ADOLESCENT DRINKING

    SBC: Rci Inc.            Topic: N/A

    N/A

    SBIR Phase I 1985 Department of Health and Human Services
  9. HIGH AFFINITY LIGANDS FOR SPECIFIC DOPAMINE RECEPTORS

    SBC: Research Biochemicals,            Topic: N/A

    N/A

    SBIR Phase I 1985 Department of Health and Human Services
  10. A STATISTICS ORIENTED DATA ACQUISITION SYSTEM

    SBC: Significat Associates            Topic: N/A

    N/A

    SBIR Phase I 1985 Department of Health and Human Services

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