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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. GRATING-COUPLED EVANESCENT WAVE SENSOR

    SBC: CIENCIA INC            Topic: N/A

    The goal of this effort is to develop a novel label-free detection technology for application to protein microarrays. The objective of the Phase I is to build a breadboard prototype to characterize the performance of this new approach and to establish feasibility. The technology is based on a multilayer grating-coupled (MGR) evanescent wave sensing method with the potential to provide highly mul ...

    SBIR Phase I 2002 Department of Health and Human ServicesNational Institutes of Health
  2. SYSTEM FOR HIGH THROUGHPUT PROTEOME CHARACTERIZATION

    SBC: CIENCIA INC            Topic: N/A

    N/A

    SBIR Phase I 2002 Department of Health and Human ServicesNational Institutes of Health
  3. SURFACE PLASMON RESONANCE PROTEIN ARRAY PHENOTYPING

    SBC: CIENCIA INC            Topic: N/A

    A microarray-based system for label-free, high throughput protein expression in profiling in very small volumes of tissue or blood (approximately 10 mL) is proposed. The system will consist of an instrument, and a proteomic biosensor chip integrated into a fluidics cartridge. It utilizes a novel grating-coupled surface plasmon resonance (GC-SPR) imaging technology that will enable measurement of t ...

    SBIR Phase I 2002 Department of Health and Human ServicesNational Institutes of Health
  4. ADVANCED IMAGING TECHNOLOGY FOR BIOCHIP ANALYSIS

    SBC: CIENCIA INC            Topic: N/A

    DESCRIPTION (provided by applicant)The broad objective of this Fast Track project is to develop and commercialize a versatile and inexpensive CCD-based system for microarray imaging and quantification. A differentiating feature of this system will be the capability to perform time-gated imaging, which will provide the benefits of effective background suppression on certain substrates such as membr ...

    SBIR Phase I 2002 Department of Health and Human ServicesNational Institutes of Health
  5. INTERNET CARELINK FOR PEDIATRIC HOME CHEMOTHERAPY

    SBC: CLINICIAN SUPPORT TECHNOLOGY, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): We propose to evaluate Pediatric Cancer CareLink, an Internet-based system designed to support home management of childhood leukemia. Protocols for childhood leukemia involve multiple cycles of chemotherapy that can be administered at home. However, the proper administration of these potentially life-saving medications in the home is a safety issue. Pediatric C ...

    SBIR Phase I 2002 Department of Health and Human ServicesNational Institutes of Health
  6. KIDNEY TRANSPLANT CARELINK

    SBC: CLINICIAN SUPPORT TECHNOLOGY, INC.            Topic: N/A

    We propose Kidney Transplant CareLink, an Internet-based learning, communication, and care support application that will help kidney transplant recipients improve their self-management skills and their ability to maintain immunosuppressive regimens over time using learning and intervention strategies, including individualized teaching, reminders, interactive counseling, monitoring, and peer suppor ...

    SBIR Phase I 2002 Department of Health and Human ServicesNational Institutes of Health
  7. DEVELOPMENT OF AN INTRANASAL ROTAVIRUS SUBUNIT VACCINE

    SBC: PARALLEL SOLUTIONS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Rotavirus disease causes nearly 1 million infant deaths annually worldwide. The only approved rotavirus vaccine, a live vaccine, was withdrawn from the market in 1999 because of association with intussusception. The safety concerns associated with live vaccines currently in development can be remedied by the development of an efficacious and safe subunit muc ...

    SBIR Phase I 2002 Department of Health and Human ServicesNational Institutes of Health
  8. ANTI-HIV PHARMACEUTICAL TARGETING CXCR4

    SBC: CONSENSUS PHARMACEUTICALS, INC.            Topic: N/A

    DESCRIPTION (Provided by the applicant): The chemokine receptor CXCR4 has been identified as a co-receptor for the infection of cells by HIV and is thought to play a key role in the progression to AIDS. We have used a highly diverse, oriented peptide library approach to identify small peptide ligands for CXCR4. The goals of this research are to characterize the CXCR4 inh ...

    SBIR Phase I 2002 Department of Health and Human ServicesNational Institutes of Health
  9. ANTI-HIV PHARMACEUTICAL TARGETING CD4

    SBC: CONSENSUS PHARMACEUTICALS, INC.            Topic: N/A

    The first stage of HIV infection begins with the viral particle binding to the CD4 protein on target cells. HIV binds to the first extracellular domain of CD4 (Domain 1). The goal of this research is to identify a high-affinity ligand for this region of CD4 and block the binding of HIV. We will make use of an "oriented peptide library" approach that selects high-affinity binders from a highly dive ...

    SBIR Phase I 2002 Department of Health and Human ServicesNational Institutes of Health
  10. FMRI TASK DESIGN AND STATISTICAL ANALYSIS SOFTWARE

    SBC: Cortechs Labs, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): The overall goal of the project is to develop a new generation of functional MRI design and analysis software. The proposed software is designed to lead to an order of magnitude improvement over current methods in the estimation and detection of fMRI activation. This phase II project has three main aims: 1. to extend the utilization of a optimal spatial filte ...

    SBIR Phase I 2002 Department of Health and Human ServicesNational Institutes of Health
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