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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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A Novel Synthetic Biology-Derived Microbiome Therapeutic to Treat Viral-Induced Acute Respiratory Distress Syndrome (ARDS)
SBC: Rise Therapeutics, LLC Topic: NIAIDPROJECT SUMMARY Acute respiratory distress syndrome (ARDS) is a severe life-threatening complication that can be caused by viral infection. The disease is characterized by cytokine-driven hyperinflammation and leukocytes count changes. The innate immune response has been linked to ARDS immunopathogenesis. In this regard, neutrophils have been highlighted as essential effector cells in the developm ...
SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
Preclinical Development of a Novel Gene Therapeutic for Inclusion Body Myositis
SBC: AAVOGEN INC Topic: NIAPROJECT SUMMARY. Gene therapy offers hope to patients with sporadic inclusion body myositis (IBM). This chronic rare disease exclusively affects older adults and results from inflammation rather than genetic mutations. Thus, it cannot be treated with gene replacement or gene editing approaches yet durable solutions like gene therapies are needed to address the progressive muscle degeneration. Such ...
SBIR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health -
Artificial Intelligent Augmented Reality Police E-Trainer for Culturally Competent De-Escalation and Non-Lethal Force Police Training to Eradicate Police Violence Against Black Males
SBC: JUXTOPIA LLC Topic: NIMHDPROJECT SUMMARY/ABSTRACTPolice violence against black males, in the United States (U.S.), is a public health disparity [37]. Physical andpsychological violence that is structurally mediated by systems of law enforcement, results in deaths, injuries,trauma, and stress that disproportionately affect blacks in the U.S. According to a 2019 study, published in theProceedings of the National Academy of ...
SBIR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health -
Design and Engineering of Biodegradable 3D Nanoprinted Microcarriers for HIV Drug Delivery
SBC: INFRATRAC INC Topic: NIAIDPrecise, customizable drug delivery remains a long-term goal, for HIV in particular, as such technologies would allow therapies tailored to a patient’s biological makeup and potentially improve adherence. Extended-release methods address part of the issue, but face limitations. A novel drug delivery system could offer better pediatric dosing, via both oral and new routes of administration. Exist ...
STTR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health -
A Normal Paradigm to Monitor Perinatal Asphyxia Using A Combined Ultrasound-Neuromodulation and Photoacoustic-Imaging Device
SBC: BRIMROSE TECHNOLOGY CORP Topic: NIBIBPROJECT SUMMARYThe Brimrose Technology Corporation and partner, The Johns Hopkins University, propose using non-invasive ultrasound neuromodulation to identify hypoxic-ischemic encephalopathy (HIE) in newborns to reduce death and lifelong brain injury. HIE is the leading cause of neonatal death and impacts 2-6 of every 1,000 live births in the developed world. Our goal is to investigate and demons ...
STTR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health -
Augmented Reality Real-Time Guidance for MRI-Guided Interventions
SBC: CLEAR GUIDE MEDICAL, INC. Topic: NIBIBProject Summary The objective of this proposal is to move into clinical practice the result of a preceding Phase I project, a compact instrument guidance system that allows physicians to see instruments advancing through an MRI volume without utilizing special needles, special headgear or calibration steps. MRI-guidance has been used for percutaneous needle injections to diagnose and treat neuropa ...
SBIR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health -
Glycoengineering of CHO cells to express recombinant alpha-1 antitrypsin
SBC: NEUIMMUNE BIOLOGICS, INC. Topic: NHLBIABSTRACTAlpha-1 antitrypsin (A1AT) is well-established as a biotherapeutic used for the treatment of alpha-1 antitrypsin deficiency, and shows promise for treating a variety of other diseases. However, A1AT augmentation therapy carries unnecessary risk since it relies upon the weekly transfusion of plasma-derived product, which presents supply chain and contaminant risks. This could be remedied wi ...
STTR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health -
Advanced Prediction of Emerging Respiratory Decline with the Linshom Continuous Predictive Respiratory Sensor (CPRS)
SBC: LINSHOM MEDICAL INC Topic: NHLBIAbstract: This Fast-track SBIR application will fund and enable a new approach to respiratory monitoring, continuous predictive respiratory monitoring (CPRM), that stands to reduce morbidity and mortality due to respiratory compromise, while reducing health care system costs. Current devices and systems (human and machine) for respiratory monitoring are responsive by sounding a warning alarm when ...
SBIR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health -
Joyuus: A Web-based Tool for Postpartum Care Self-care to Address the Complex Needs of Underserved Women
SBC: JOYUUS, LLC Topic: 100PROJECT SUMMARY/ABSTRACT In the United States, the postpartum period is a critical time for both maternal and child health; the US maternal mortality rate is the highest among other developed, high-income countries. More than half of all maternal deaths occur postpartum, from one day to one year after birth.1-9 There are vast racial and ethnic disparities in maternal mortality and severe morbidity ...
SBIR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health -
Development and Evaluation of Computerized Chemosensory-Based Orbitofrontal Networks Training for Treatment of Pain (CBOT-P)
SBC: EVON MEDICS LLC Topic: 107PHASE I/II (FAST/TRACK) ABSTRACTThe Development and Evaluation of Computerized Chemosensory-Based Orbitofrontal Networks Training for Treatment of Pain (CBOT-P) is a project to develop an effective, scalable, user-friendly, and home- based neuromodulatory platform for broad-spectrum treatment of chronic pain conditions with associated negative affect and cognitive impairments. Chronic pain (CP) af ...
SBIR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health