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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. SBIR TOPIC 454: A SOFTWARE TOOL FOR STANDARDIZATION OF RADIOTHERAPY TREATMENT PLANS FOR AI VALIDATION

    SBC: ONCOSPACE INC            Topic: 454

    The goal of this proposal is to create a medical device development tool (MDDT) for use during performance evaluation of artificial intelligence (AI)-based radiotherapy software. The MDDT is intended to be used by manufacturers during external validation, whereby AI models are tested for generalizability. Test results can be used for pre-market submissions to the Food and Drug Administation (FDA) ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  2. CRISPR-based Diagnostic for Parasites

    SBC: BIOLOGICAL MIMETICS, INC.            Topic: 119

    To develop a sensitive point-of-care diagnostic for an important neglected tropical disease, Leishmaniasis.

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  3. COGNITIONCARE: A NOVEL AI/ML TOOL FOR EXPLORING CAUSAL RELATIONSHIPS IN AD/ADRD-FOCUSED BSR LITERATURE

    SBC: LEXICAL INTELLIGENCE, LLC            Topic: 9

    The objective of this contract is to develop a tool that allows researchers to identify preventions for AD/ADRD through access to and analysis of the vast array of BSR literature. Cognition Causal Association Record Extractor (CognitionCARE) is an AI-based web application that presents AD/ADRD-specific, BSR-related information in a manner that is easy to consume and act upon. CognitionCARE extract ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  4. PROVIRAL SEQUENCING DRIVEN DEVELOPMENT OF ENHANCED IPDAV2 WITH GLOBAL HIV-1 GROUP M COVERAGE TO SUPPORT WORLDWIDE CURE AND CLINICAL TRIALS

    SBC: ACCELEVIR DIAGNOSTICS LLC            Topic: 78

    The objective of this program is to develop and commercialize sequence-based HIV reservoir assays for clinical HIV cure interventions. The assay should be designed as an analytical tool to monitor the size of the replication-competent HIV reservoir in clinical research and in prospective clinical trials. An additional goal of the program is to develop secondary assays that are not tissue culture-b ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  5. Using Interactive Digital Media to Teach Cardiopulmonary Resuscitation to High School Students

    SBC: CORAM TECHNOLOGIES, INC.            Topic: 500

    Abstract Out-of-hospital cardiac arrest affects over 350,000 people in the U.S. annually, but only 10.8% survive. Bystander cardiopulmonary resuscitation (CPR) improves survival, but rates of training in the U.S. are low. It is recently required by law in 39 U.S. states that high school students learn CPR. However, current methods of teaching CPR use outdated pedagogical strategies and expensive d ...

    STTR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  6. Non Magnetic MRI Conditional External Defibrillator with Reduced Skeletal Muscle Contraction

    SBC: CORAM TECHNOLOGIES, INC.            Topic: NHLBI

    There are over 36 million MRI scans done each year in the United States, and anesthesia or sedation is used in a significant number of those scans. This is especially true in pediatrics where as many as 28% of MRI scans are done with anesthesia, and the increased use of anesthesia has increased the utilization of MRI. It has long been known that cardiac arrest from ventricular fibrillation can com ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  7. High accuracy automated tick classification using computer vision

    SBC: VECTECH, INC.            Topic: NIAID

    Abstract. The incidence of US tick-borne diseases has more than doubled in the last two decades. Today, Lyme disease is the most common vector-borne disease in the United States, impacting over half-a-million Americans each year. Due to lack of effective vaccines for tick-borne diseases, prevention of tick bites and early tick bite treatment is the primary focus of disease mitigation. Tick vector ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  8. A scalable aptamer-based electrochemical biosensor for rapid detection of SARS-CoV-2 from saliva

    SBC: MPOD INC            Topic: NIDCR

    Abstract The COVID-19 pandemic is a critical global public health emergency and many countries are failing to contain the virus's spread due to slow and insufficient testing. While several diagnostic methods are now available, most tests are either reagent-intensive and must be done in CLIA-approved labs, making them expensive and slow to report results, or rapid and inexpensive, but potentially l ...

    SBIR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
  9. Design and Engineering of Biodegradable 3D Nanoprinted Microcarriers for HIV Drug Delivery

    SBC: INFRATRAC INC            Topic: NIAID

    Precise, customizable drug delivery remains a long-term goal, for HIV in particular, as such technologies would allow therapies tailored to a patient’s biological makeup and potentially improve adherence. Extended-release methods address part of the issue, but face limitations. A novel drug delivery system could offer better pediatric dosing, via both oral and new routes of administration. Exist ...

    STTR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  10. Developing Vertebrate-Specific Replication-Defective Dengue Virus as Novel Single-CycleDengue Vaccine Candidate

    SBC: Tengen Biomedical Co            Topic: NIAID

    Developing Vertebrate-Specific Replication-Defective Dengue Virus asa Novel Single-Cycle Dengue Vaccine Candidate Abstract With an estimated minimum of 390 million dengue virus (DENV) infections per year, the DENV epidemic was listed as one of the world's top 10 public health threats by WHO in 2019. At present, there is no specific treatment. A universal vaccine is urgently needed. DENV vaccine de ...

    STTR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
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