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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Behavioral feedback and rewards for improving functional brain mapping in presurgical pediatric patients

    SBC: TURING MEDICAL TECHNOLOGIES INC            Topic: 106

    Project Abstract/Summary The objective of this psychological technology SBIR/STTR Fast-Track proposal is to provide an innovative gamified biofeedback solution (software-only) to improve the effectiveness of functional Magnetic Resonance Imaging (fMRI) for pediatric pre-neurosurgical planning. Maximal safe resection of an epileptic focus to optimize outcome is carefully balanced against impact on ...

    SBIR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  2. Use of a novel physiologic measure for the assessment and monitoring of vincristine induced peripheral neuropathy (VIPN) in children and adolescents.

    SBC: ALGOMETRX INC            Topic: 102

    In this application, we propose the examination of a novel physiologic measure of vincristine-induced peripheral neuropathy (VIPN) in pediatric patients. Establishment of such a measure will enable the objective characterization of both the positive and negative symptoms of neuropathy in pediatric patients treated with vincristine in order to enable early detection and management of the resulting ...

    SBIR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  3. Development of Sotair for Improving Performance and Minimizing Complications of Manual Ventilation

    SBC: SAFEBVM CORP.            Topic: NHLBI

    Abstract Bag valve mask (BVM) resuscitators are the gold standard of emergency airway management and artificial respiration for patients who are not breathing adequately. However, a well-documented problem with BVMs is that they are often misused, regardless of the qualifications and experience of the provider, which can lead to dangerous complications such as gastric insufflation. Gastric insuffl ...

    SBIR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
  4. Rapid dissection of the biosynthesis of antiMRSA antibiotics produced in co-culture by extremophilic fungi through the development of Fungal Artificial Chromosomes

    SBC: INTACT GENOMICS INC            Topic: NIAID

    PROJECT SUMMARY. The economic and social burden of the treatment of infectious and chronic diseases is enormous, rt$300B annually. The ongoing COVID-19 pandemic alone will cost the U.S. economy roughly $8 trillion over the next decade without an effective drug to date. The emergence of drug resistant microbes, the diminishing supply of novel classes of antibiotics, and the dramatic reduction in Ra ...

    SBIR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
  5. High performance and widely accessible secretomics assay platform

    SBC: Auragent Bioscience LLC            Topic: 400

    AbstractSecretory proteins are fundamental to local and systemic cellular signaling in biological systems. The regulation and dysregulation of the networks involving these proteins plays a critical role in health, aging, and development of disease. As such, study of these proteins and their networks is critical to our understanding of biology. Not surprisingly, this particular set of proteins cons ...

    SBIR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
  6. Development of a novel technology for the determination of a physiologic phenotype in patients with Systemic Lupus Erythematosus

    SBC: ALGOMETRX INC            Topic: NIAMS

    In this application, we propose the initial validation of a novel medical device for the measurement of systemic lupus erythematosus (SLE) disease activity. SLE is a complex inflammatory disease involving many organ systems. The existing assessment tools and laboratory tests used to track inflammation do not reliably reflect patient reported symptoms. Furthermore, these biomarkers are unable to pr ...

    SBIR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  7. Innovation of Biobanking for Cellular Adoptive Immunotherapies Based on a First-in-Class Biocompatible Cryopreservation Technology for T and NK Cells and Their CAR-Engineered Products

    SBC: CRYOCRATE LLC            Topic: NCI

    SUMMARY Previous support from NIH SBIR and Coulter Foundation awards allowed the CryoCrate team to develop a first- in-class biocompatible cryopreservation medium product that doesn’t need any cell permeating and toxic cryoprotectant. The product is trademarked as OdinSol®, and has been approved to provide significantly improved efficiency in cryostorage of cell types that are essential for cel ...

    SBIR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
  8. Magnetic Rotational Exploratory Platform for Coronary Lesions

    SBC: UNANDUP, LLC            Topic: NHLBI

    Cardiovascular disease (CVD) is the leading cause of mortality in the United States (US), resulting in 850,000 annual deaths, of which nearly 400,000 are associated with coronary heart disease (CHD) and myocardial infarction (MI). By 2030, global annual deaths will exceed 20 million. More than 90 million US adults currently live with CVD, which is associated with an annual economic burden of more ...

    SBIR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  9. Barcoded human cells engineered with heterozygous genetic diversity to uncover toxicodynamic variability

    SBC: AMELIA TECHNOLOGIES LLC            Topic: R

    Project Summary Current in vitro approaches for laboratory- and cell-based toxicology studies do not capture the interindividual variability in responses within the human population. Single nucleotide gene polymorphisms, gene heterozygosity, variations in gene expression and in some cases gene loss can yield highly variable responses to genotoxic compounds, ranging from hypersensitivity to complet ...

    SBIR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
  10. Rapid Terrain/Map Generation for Robotic and Autonomous Vehicle Simulations

    SBC: LICKENBROCK TECHNOLOGIES, INC.            Topic: A20129

    The objective of this project is to build 3D terrain models from satellite imagery and Digital Elevation Maps (DEM) using the Unreal Engine platform. Terrain and other objects are added to the 3D model by classifying objects from RGB satellite images. The classification of objects is typically the most time-consuming step within the entire process, which is currently done manually by a user. In P ...

    SBIR Phase I 2021 Department of DefenseArmy
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