Award Data

DESCRIPTION (provided by applicant): The goal of this new SBIR program is to produce a combined clotting Factor VIII replacement and immunomodulatory therapy that will provide FVIII-specific tolerance induction at therapeutic doses for Hemophilia A patients. Hemophiliacs with lt 1% functional FVIII are classified as severe and must receive regular doses of replacement factor. A major issue with su ...

DESCRIPTION (provided by applicant): Cardiac output (CO) monitoring can improve the outcomes of critically ill patients via early detection and diagnosis of disease and goal-directed therapy. Yet, CO monitoring has sharply declined due to its invasiveness.Retia Medical will offer a device that computes CO by mathematical analysis of minimally invasive and non-invasive physiologic waveforms that ar ...

DESCRIPTION (provided by applicant): This proposal aims to ensure the ability of NLP-Standalone-or-Hybrid Documentation, a method of EHR data capture involving Natural Language Processing and possibly also standard EHR data capture, to improve the usability of EHR by reducing documentation time, increasing documentation quality, and increasing clinician satisfaction. Problem to be Addressed. L ...

DESCRIPTION (provided by applicant): With the successful launch of Apple's iPad, the markets for mobile tablets have exploded. Such mobile tablets are fast becoming a standard part of education. Here we propose to develop a new 3D cadaver exploration software called Mobile Cadaver Lab (MCL) designed specifically for the mobile tablet market. In Phase I, we will explore the feasibility of a re ...

DESCRIPTION (provided by applicant): Over the past 10 years it has become increasingly apparent that there is exceptional complexity in the RNA population in cells, including microRNAs, Piwi-interacting RNAs, termini-associated RNAs and other noncoding RNAs. In many cases, alterations in these RNAs, or proteins that bind to these RNAs, have been linked to a wide range of medical disorders. A major ...

DESCRIPTION (provided by applicant): Patient data collected during health care delivery and public health surveys possess a great deal of information that could be used in biomedical and epidemiological research. Access to these data, however, is usually limited because of the private nature of most personal health records. Methods of balancing the informativeness of data for research with the inf ...

DESCRIPTION (provided by applicant): Ai Cure Technologies LLC, was established in 2009 to develop computer vision solutions to ensure safer medication usage. This SBIR Phase I will allow Ai Cure Technologies to prove feasibility of an innovative identification and anti-counterfei labeling solution that replaces traditional barcodes and utilizes the self-similarity properties of fractals to encode ...

DESCRIPTION (provided by applicant): Mortality from colorectal cancer (CRC) can be reduced through screening programs. Regardless of the primary strategy (fecal occult blood testing, sigmoidoscopy, colonoscopy, fecal DNA, computed tomographic colonography[virtual colonoscopy]) colonoscopy is required to evaluate positive screening tests and to detect or remove colonic neoplasia. Colonoscopy qualit ...

DESCRIPTION (provided by applicant): Due to its complex, multi-herb nature, many patients who use Complementary and Alternative Medicine (CAM) do not have full knowledge of the ingredients included in their remedies. Lack of disclosure about CAM can placepatients at risk, as some herbal products can have adverse interactions with pharmaceuticals or cause harmful side effects. This proposal seeks t ...

DESCRIPTION (provided by applicant): This grant application is by Ion Channel Innovations, LLC, (ICI) a company dedicated to the development of naked DNA transfer to treat the unmet needs of people with common smooth muscle diseases that negatively impactthe quality of life of millions. Overactive bladder syndrome (OAB), characterized by symptoms of urinary urgency, frequency, and incontinence, is ...