Award Data

One of the most important infectious diseases affecting the health of military recruits is adenovirus, which causes acute outbreaks of respiratory disease in military facilities incapacitating personnel, burdening hospitals, disrupting military operations and increasing medical costs. We propose to continue the development of a new generation of adenovirus vaccines based on adenovirus-like particl ...

An enormous military and civilian need exists to develop capabilities for salvage, preservation and re-implantation of genitourinary tissues and especially reproductive organs. Yet methods for salvaging and clinical banking of whole testes are non-existent, while approaches to bank whole ovaries have been attempted thus far and have resulted in mixed successes. Reproductive organ banking has yet t ...

Vascular trauma is the leading cause of death in military environments and hemorrhage is the major preventable cause of mortality among trauma patients. Recent experience from Iraq and Afghanistan has demonstrated improved 24-h and 30-day survival in combat casualties requiring early massive transfusion. Unlike plasma and erythrocytes, which can be cold stored for longer time periods, platelets ca ...

Hypres is pleased to submit this proposal to continue its Phase II SBIR program and complete the development of a combat-area portable digital MRI (Magnetic Resonance Imaging) system capable of high-resolution Traumatic Brain Injury (TBI) diagnosis in field hospitals. This sequential Phase IIc SBIR program will produce and demonstrate a near production ready state-of-the-art portable MRI system at ...

VitaMe Technologies Inc. and Cornell University will develop the FePhone - a point-of-care diagnostic system for iron status determination.The FePhone comprises of (1) a test cartridgewhich accepts the blood sample and performs the test, (2) a TidBit readera custom portable hardware system developed by Cornell which operates the test, and (3) a mobile appwhich provides step-by-step instructions fo ...

Iron deficiency is one of the most common nutritional deficiencies in the United States. Left untreated, iron stores continue to deplete, resulting in iron deficiency anemia. Women undergoing basic military training are particularly susceptible to reduced iron stores. To date, there are no comprehensive point-of-care instruments for accurate determination of iron status. We propose to develop a no ...

Surgical simulations aiming to support surgeon practices and medical education have attracted enormous research effort over the last two decades. However, the physical reality, especially on simulating aggregated tissue interaction, is still unsatisfactory. In this proposed work, an open source surgery simulation framework, SoFMIS, will be utilized and enhanced with tissue interaction models to a ...

The DOD is investing in mobile computing, information and warrior health systems to support network-centric military capabilities. Computerized health records, telemedicine, wearable monitoring, mHealth have the potential to reduce costs, promote health, ensure soldier fitness. The goal of this project is to design, develop, demonstrate, deploy a Warfighter Health Avatar (WHA), a simulation framew ...

Use ofexisting smaller prosthetic grafts for vascular repair and reconstruction after severetrauma to the extremities is greatly limited by issues with stenosis and infection.We propose treating the exterior of ePTFE vascular grafts with STAR biomaterial, a well-developed microporous synthetic tissue scaffold already in human use.STAR prevents the usual formation of a constrictive fibrotic perigra ...

Trauma is the leading cause of death in civilian and military environments and acute hemorrhage contributes to a large portion of these fatalities. Recent experience from Iraq and Afghanistan has demonstrated the crucial role of blood products in the care of critically injured soldiers. Unlike plasma and red blood cells, which can be cold stored for longer time periods, platelets can be safely sto ...